Paul Bégin
Université de Montréal
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Paul Bégin.
Journal of Sleep Research | 2004
Luc Laberge; Paul Bégin; Jacques Montplaisir; Jean Mathieu
The aim of this study was to document the clinical picture of excessive daytime sleepiness (EDS) and of other sleep disturbances, and to study the relationship of daytime sleepiness to anthropometric data, muscular impairment, and CTG trinucleotide repeat expansion in myotonic dystrophy type 1 (DM1). A total of 157 DM1 patients were surveyed using a modified version of the Sleep Questionnaire and Assessment of Wakefulness. Other measurements included muscular impairment rating and the size of the trinucleotide repeat. Factor analysis and reliability estimates were used to produce a daytime sleepiness scale with five items of the questionnaire. Thirty‐eight healthy family members were studied as control subjects. It was found that EDS was present in 33.1% of DM1 patients. Severity of daytime sleepiness correlated with the degree of muscular impairment but not with age, gender, body mass index, age at onset of symptoms, duration of illness, and CTG repeat. DM1 patients reported a longer sleep period, a less restorative sleep, and more difficulty falling asleep, being alert in the morning and staying awake after meals than controls, but a similar incidence of narcolepsy auxiliary symptoms. Compared with DM1 patients without EDS, those with EDS reported greater hypnagogic hallucinations, and greater pain associated with nocturnal awakenings and in their legs upon morning awakenings. In sum, both DM1 patients with and without EDS exhibit characteristics of sleep duration and sleepiness comparable with those found in idiopathic hypersomnia. The severity of daytime sleepiness is weakly related to the extent of muscular impairment but not to CTG repeat.
Neuromuscular Disorders | 2009
Luc Laberge; Yves Dauvilliers; Paul Bégin; Louis Richer; Stéphane Jean; Jean Mathieu
We assessed the relationship and clinical correlates of fatigue and Excessive Daytime Sleepiness (EDS) in 200 myotonic dystrophy type 1 (DM1) patients by means of questionnaire and neuropsychological evaluation. Fatigue levels were higher in patients with EDS and daytime sleepiness levels higher in patients with excessive fatigue. However, EDS without fatigue was rarely observed. Also, DM1 patients with fatigue (with or without EDS) showed greater muscular impairment, CTG repeats, abnormalities regarding personality, depressive symptoms and lower health-related quality of life (HRQoL) than patients without these symptoms. These findings do not readily support the contention that fatigue and EDS constitute distinct clinical manifestations in DM1. Clinicians should systematically evaluate both symptoms since fatigue and EDS have a greater impact on HRQoL than fatigue alone. However, specific rating scales for fatigue in DM1 have yet to be devised.
Canadian Respiratory Journal | 2004
José Almirall; Paul Bégin
Ongoing spirometry quality standards are difficult to bring into the daily routine of general practice. As a result, spirometry is rarely performed by primary care physicians. A new approach is proposed: exclusion spirometry. Acceptable and reproducible results are sought. However, the goal of the test is to try to reach values within normal limits, even if results do not reach quality standards. Normal results would be sufficient to exclude respiratory impairment, except in asthma. Abnormal results would require further testing in a diagnostic spirometry laboratory. The aim of the initiative is to enhance the compliance of general practitioners in using spirometers for screening.
The American review of respiratory disease | 1991
Paul Bégin; Alejandro Grassino
American Journal of Respiratory and Critical Care Medicine | 1997
Paul Bégin; Jean Mathieu; José Almirall; Alejandro Grassino
The Journal of Infectious Diseases | 1991
François Coutlée; Pierre Saint-Antoine; Clément Olivier; Allégria Kessous-Elbaz; Hélène Voyer; Fouad Berrada; Paul Bégin; Lise Giroux; Raphael P. Viscidi
Chest | 1987
André Gervais; Paul Bégin
Journal of Clinical Microbiology | 1991
François Coutlée; Pierre Saint-Antoine; Clément Olivier; Hélène Voyer; Allégria Kessous-Elbaz; Fouad Berrada; Paul Bégin; Lise Giroux; Raphael P. Viscidi
The American review of respiratory disease | 2015
Paul Bégin; R. Peslin
Chest | 2000
Paul Bégin; Alejandro Grassino