Paul Edward Floreancig

Archive Network Publication Hotspot Collaboration

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Paul Edward Floreancig is active.

Explore More

Publication

Featured researches published by Paul Edward Floreancig.

Bioorganic & Medicinal Chemistry Letters | 1993

Acid unit modifications of 1,2,4,5-substituted hydroxyacetophenones and the effect on in vitro and in vivo LTB4 receptor antagonism

Michael J. Sofia; Paul Edward Floreancig; William T. Jackson; Philip Marder; David L. Saussy; Steven A. Silbaugh; Sandra L. Cockerham; Larry L. Froelich; Carlos R. Roman; Peter W. Stengel; Jerome H. Fleisch

7-[4-Acetyl-2-ethyl-5-hydroxyphenoxy)propoxy]-3,4-dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid sodium salt 7 (LY247826) and several 7-[3-(4-acetyl-2-ethyl-5-hydroxyphenoxy)propoxy)-2-propylphenoxy] acetic acid analogues were prepared as LTB4 receptor antagonists. When compared with LY255283 and SC-41930, these antagonist showed improved in vitro LTB4 receptor antagonism and/or in vivo activity.

Archive | 1994

Substituted phenyl phenol leukotriene antagonists

S. Richard Baker; Robert D. Dillard; Paul Edward Floreancig; J. Scott Sawyer; Michael J. Sofia

Journal of Medicinal Chemistry | 1995

Synthetic and Structure/Activity Studies on Acid-Substituted 2-Arylphenols: Discovery of 2-[2-Propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxyphenoxy]- propoxy]phenoxy]benzoic Acid, a High-Affinity Leukotriene B4 Receptor Antagonist

Sawyer Js; Nicholas James Bach; Baker; Baldwin Rf; Borromeo Ps; Sandra L. Cockerham; Jerome H. Fleisch; Paul Edward Floreancig; Larry L. Froelich; William T. Jackson

Journal of Medicinal Chemistry | 1993

Biphenylyl-substituted xanthones : highly potent leukotriene B4 receptor antagonists

Sawyer Js; Baldwin Rf; Michael J. Sofia; Paul Edward Floreancig; Philip Marder; Saussy Dl; Larry L. Froelich; Silbaugh Sa; Stengel Pw; Sandra L. Cockerham

Journal of Medicinal Chemistry | 1993

o-Phenylphenols: potent and orally active leukotriene B4 receptor antagonists

Michael J. Sofia; Paul Edward Floreancig; Nicholas James Bach; S. Richard Baker; Sandra L. Cockerham; Jerome H. Fleisch; Larry L. Froelich; William T. Jackson; Philip Marder

Journal of Medicinal Chemistry | 2010