Paul J. Dobrowolski | Researchain

Archive Network Publication Hotspot Collaboration

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Paul J. Dobrowolski is active.

Explore More

Publication

Featured researches published by Paul J. Dobrowolski.

Tetrahedron Letters | 1994

Taxol chemistry. 7-O-triflates as precursors to olefins and cyclopropanes

Roy A. Johnson; Eldon G. Nidy; Paul J. Dobrowolski; Ilse Gebhard; Samuel J. Qualls; Nancy Anne Wicnienski; Robert C. Kelly

Abstract 7-O-Triflates of baccatin III or of taxol analogs are convenient precursors in alternate syntheses of Δ 6,7 -taxols and 7β,8β-methano (cyclopropyl) taxols, two of the products initially obtained from reaction of taxols with methylDAST; hydrazine is an effective reagent for conversion of the 10-acetate group to the hydroxyl group.

International Journal of Peptide and Protein Research | 2009

Problems associated with use of the benzyloxymethyl protecting group for histidines Formaldehyde adducts formed during cleavage by hydrogen fluoride 1

Mark A. Mitchell; Thomas A. Runge; W. Rodney Mathews; Avneet K. Ichhpurani; Nancy K. Harn; Paul J. Dobrowolski; Frances M. Eckenrode

Organic Process Research & Development | 2001

Synthesis of 2,4-Di-1-pyrrolidinyl-9H-pyrimido[4,5-b]indoles, Including Antiasthma Clinical Candidate PNU-142731A

Gordon L. Bundy; Lee S. Banitt; Paul J. Dobrowolski; John R. Palmer; Theresa M. Schwartz; David C. Zimmermann; Michael F. Lipton; Michael A. Mauragis; Michael F. Veley; Robert Bruce Appell; and Robert C. Clouse; Edward D. Daugs

Journal of the American Chemical Society | 1996

12,13-ISOBACCATIN. III: TAXANE ENOL ESTERS (12,13-ISOTAXANES)

Robert C. Kelly; Nancy Anne Wicnienski; Ilse Gebhard; Samuel J. Qualls; Fusen Han; Paul J. Dobrowolski; Eldon G. Nidy; Roy A. Johnson

Archive | 2003

TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS

Michael R. Barbachyn; J. Craig Ruble; Arthur Glenn Romero; Lisa Marie Thomasco; Alexander R. Hurd; John R. Palmer; Peter L. Toogood; Dennis Joseph McNamara; Debra Ann Sherry; Paul J. Dobrowolski

Organic Process Research & Development | 1997

Production Scale Synthesis of the Non-Nucleoside Reverse Transcriptase Inhibitor Atevirdine Mesylate (U-87,201E)

William R. Perrault; K. Paul Shephard; Lori A. LaPean; Mark A. Krook; Paul J. Dobrowolski; Mark A. Lyster; Moses W. McMillan; Donald J. Knoechel; Gerald N. Evenson; William Watt, ,§ and; Bruce Allen Pearlman

Journal of Medicinal Chemistry | 1997

12,13-isotaxanes: synthesis of new potent analogs and X-ray crystallographic confirmation of structure.

Roy A. Johnson; Paul J. Dobrowolski; Eldon G. Nidy; Ilse Gebhard; Samuel J. Qualls; Nancy Anne Wicnienski; Robert C. Kelly; Thomas W. Pitts; Narima M. Lopes; Thomas F. DeKoning; Sally J. Mattern; Sheldon D. Weed; and J. Patrick McGovren; Constance G. Chidester

International Journal of Peptide and Protein Research | 2009

Hydrogen fluoride catalyzed migration of side chain protecting groups onto Fmoc during solid phase peptide synthesis

Stephen H. Grode; Diane S. Strother; Thomas A. Runge; Paul J. Dobrowolski

Archive | 1994

Piperazinylpyridinyl water clathrates

Bruce Allen Pearlman; Mark A. Krook; William R. Perrault; Paul J. Dobrowolski

Archive | 2003

Tricyclic tetrahydroquinolines with antibacterial effect

Michael R. Barbachyn; Paul J. Dobrowolski; Alexander R. Hurd; D J Mcnamara; John R. Palmer; Arthur Glenn Romero; James Craig Ruble; Debra Ann Sherry; Lisa Marie Thomasco; Peter L. Toogood; Gordon L. Bundy; Gary E. Martin; Donna Lee Romero

Explore More