Is this you? Create Your Porfile
Avatar

Paul Kung
Hotspot
Bubble
Bubble
[Coming Soon]
 Word Cloud
Cloud
 Mosaic Glass
Mosaic
[Coming Soon]

Archive | 2015

Small Molecules Targeting the Mitochondrial Permeability Transition

Justina Sileikyte; Sudeshna Roy; Patrick Porubsky; Benjamin Neuenswander; Jenna Wang; Michael Hedrick; Anthony B. Pinkerton; Sumeet Salaniwal; Paul Kung; Arianna Mangravita-Novo; Layton H. Smith; Dennis Bourdette; Michael R. Jackson; Jeffrey Aubé; Thomas Dy Chung; Frank J. Schoenen; Michael Forte; Paolo Bernardi

Archive | 2015

Functional Antagonists of EBI-2

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Allosteric Small Molecule Inhibitors of LMPTP

Robert Ardecky; Michael Hedrick; Stephanie M. Stanford; Matthew R. Bliss; Jiwen Zou; Palak Gosalia; Fusayo Yamamoto; Monika Milewski; Nikki Barron; Qing Sun; Santhi Ganji; Alka Mehta; Elliot Sugarman; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Eduard Sergienko; Thomas Dy Chung; Anthony B. Pinkerton; Nunzio Bottini

Archive | 2015

Inhibitors of Myocyte Triacylglyceride Accumulation

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Archive | 2015

Table 5, Summary of in vitro ADME Properties of EBI2 inhibitor probe ML401 (MLS-0472527)

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Scheme1, Synthesis of ML401, conditions: a. CDI, THF 2 to 3 hrs at RT (79%); b. DCM, TFA 0 °C; c. 4-Cl benzyl bromide, K2CO3, Acetone, 50°C 2 hours (58%)

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Figure 1, Structure of ML377

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Archive | 2015

Figure 1, EBI2 antagonist GSK682753

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Figure 3, Potency of ML377 inhibition for triacylglycerol accumulation in both H9c2 cells and differentiated human skeletal myotubes

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Archive | 2015

Table 4, Summary of in vitro ADME Properties of TAG inhibitor probe ML377

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Explore More
Researchain Logo
Decentralizing Knowledge