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Paul Kung

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Publication

Featured researches published by Paul Kung.

Archive | 2015

Small Molecules Targeting the Mitochondrial Permeability Transition

Justina Sileikyte; Sudeshna Roy; Patrick Porubsky; Benjamin Neuenswander; Jenna Wang; Michael Hedrick; Anthony B. Pinkerton; Sumeet Salaniwal; Paul Kung; Arianna Mangravita-Novo; Layton H. Smith; Dennis Bourdette; Michael R. Jackson; Jeffrey Aubé; Thomas Dy Chung; Frank J. Schoenen; Michael Forte; Paolo Bernardi

Archive | 2015

Functional Antagonists of EBI-2

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Allosteric Small Molecule Inhibitors of LMPTP

Robert Ardecky; Michael Hedrick; Stephanie M. Stanford; Matthew R. Bliss; Jiwen Zou; Palak Gosalia; Fusayo Yamamoto; Monika Milewski; Nikki Barron; Qing Sun; Santhi Ganji; Alka Mehta; Elliot Sugarman; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Eduard Sergienko; Thomas Dy Chung; Anthony B. Pinkerton; Nunzio Bottini

Archive | 2015

Inhibitors of Myocyte Triacylglyceride Accumulation

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Archive | 2015

Table 5, Summary of in vitro ADME Properties of EBI2 inhibitor probe ML401 (MLS-0472527)

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Scheme1, Synthesis of ML401, conditions: a. CDI, THF 2 to 3 hrs at RT (79%); b. DCM, TFA 0 °C; c. 4-Cl benzyl bromide, K2CO3, Acetone, 50°C 2 hours (58%)

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Figure 1, Structure of ML377

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Archive | 2015

Figure 1, EBI2 antagonist GSK682753

Robert Ardecky; Eduard Sergienko; Jiwen Zou; Santhi Ganji; Brock Brown; Qing Sun; Chen-Ting Ma; Becky Hood; Kevin Nguyen; Stefan Vasile; Eigo Suyama; Arianna Mangravita-Novo; Sumeet Salaniwal; Paul Kung; Layton H. Smith; Thomas Dy Chung; Michael R. Jackson; Anthony B. Pinkerton; Robert C. Rickert

Archive | 2015

Figure 3, Potency of ML377 inhibition for triacylglycerol accumulation in both H9c2 cells and differentiated human skeletal myotubes

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

Archive | 2015

Table 4, Summary of in vitro ADME Properties of TAG inhibitor probe ML377

Paul M. Hershberger; Eliot Sugarman; Patrick Maloney; Satyamaheshwar Peddibhotla; Ada Koo; Eigo Suyama; Manuel E. Ruidiaz; Susanne Heynen-Genel; Kevin H. Nguyen; Stefan Vasile; Arianna Mangravita-Novo; Layton H. Smith; Mangala M. Soundarapandian; Sumeet Salaniwal; Paul Kung; Rick B. Vega; Thomas Dy Chung; Anthony B. Pinkerton; Siobhan Malany; Daniel P. Kelly

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Collaboration

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Matthew R. Bliss

La Jolla Institute for Allergy and Immunology

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Nunzio Bottini

La Jolla Institute for Allergy and Immunology

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Patrick Maloney

Research Triangle Park

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Stephanie M. Stanford

La Jolla Institute for Allergy and Immunology

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Rick B. Vega

University of Texas Southwestern Medical Center

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Daniel P. Kelly

University of Utah

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Justina Sileikyte

University of Padua

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Paolo Bernardi

University of Padua

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Benjamin Neuenswander

Iowa State University

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Chi K. Leung

University of Florida

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