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Dive into the research topics where Paul Mcglynn is active.

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Featured researches published by Paul Mcglynn.


Aerosol Science and Technology | 2010

Inversion of Andersen Cascade Impactor Data using the Maximum Entropy Method

Yuriy Gulak; Eric Jayjock; Fernando J. Muzzio; Andrea Bauer; Paul Mcglynn

The problem of the Andersen cascade impactor data inversion is studied using the maximum entropy method to recover the particle size distribution function from a set of measured masses collected on the impactor stages. The classical entropy maximization and its modification to accommodate data errors are reviewed using the techniques of convex optimization. Numerical experiments were performed to test the method on several unimodal and multimodal distributions commonly observed in practice. The Maximum Entropy Method for data inversion produced excellent agreement between the recovered and test Particle Size Distribution Functions without the need for a priori assumptions.


International Journal of Pharmaceutics | 2009

Numerical calibration of the Andersen cascade impactor using a single jet model

Yuriy Gulak; Eric Jayjock; Fernando J. Muzzio; Andrea Bauer; Paul Mcglynn

A single jet model is described and used to analyze the performance of an 8-stage Andersen cascade impactor (ACI). The two-dimensional axisymmetric jet flow field was calculated numerically by solving the Navier-Stokes equations and particle trajectories were then analyzed to obtain the collection efficiency curves at different flow rates. The resulting efficiency curves and corresponding cutoff diameters were compared and found to be in good agreement with the available experimental data. We also examined the effect of gravity on impactor performance and discuss the limitations of the single jet model.


Respiratory Care | 2009

The Influence of Breathing Pattern During Nebulization on the Delivery of Arformoterol Using a Breath Simulator

Andrea Bauer; Paul Mcglynn; Li Li Bovet; Pamela L Mims; Lisa Curry; John P. Hanrahan


Respiratory Care | 2009

Output and Aerosol Properties of 5 Nebulizer/Compressor Systems With Arformoterol Inhalation Solution

Andrea Bauer; Paul Mcglynn; Li Li Bovet; Pamela L Mims; Lisa Curry; John P. Hanrahan


Chest | 2007

THE INFLUENCE OF BREATHING PATTERN DURING NEBULIZATION ON THE EMITTED DOSE OF ARFORMOTEROL

Andrea Bauer; Paul Mcglynn; Li Li Bovet; P. Mims; Lisa Curry; John P. Hanrahan


Archive | 2014

ARFORMOTEROL AND TIOTROPIUM COMPOSITION AND METHOD FOR USE

Huang Holly; Elizabeth Goodwin; Kendyl Schaefer; John Hanrahan; William T. Andrews; Paul Mcglynn


Archive | 2012

Produit aérosol pharmaceutique pour l'administration par inhalation orale ou nasale

Helgert Müller; Renate Engelstätter; Ulrich Bildmann; Andrea Bauer; Paul Mcglynn


Archive | 2012

Pharmazeutisches aerosolprodukt zur verabreichung mittels oraler oder nasaler inhalation

Helgert Müller; Renate Engelstätter; Ulrich Bildmann; Andrea Bauer; Paul Mcglynn


Archive | 2009

Arformoterol and tiotropium compositions and methods for use

Holly Huang; Elizabeth Goodwin; Kendyl Schaefer; John P. Hanrahan; William T. Andrews; Paul Mcglynn


Archive | 2003

pharmaceutical composition comprising L-hemitartrate salt of levalbuterol as aerosol formulation

Paul Mcglynn; Roger P. Bakale; Craig Sturge

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