Peter Frigo
University of Vienna
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Featured researches published by Peter Frigo.
Obstetrics & Gynecology | 1998
Peter Frigo; Christine Lang; Klaus Reisenberger; H. Kölbl; Alexander M. Hirschl
Objective To test the hypothesis that infection with Helicobacter pylori is associated with hyperemesis gravidarum. Methods From January 1995 to November 1996 we enrolled 105 patients with hyperemesis gravidarum in a prospective study. The Helicobacter serum Immunoglobulin (Ig) G concentrations in these patients were compared with those in asymptomatic gravidas matched for week of gestation. Results Positive serum IgG concentrations were found in 95 of the 105 hyperemesis patients (90.5%) compared with 60 of 129 controls (46.5%). A χ2 test showed statistical significance (P < .001). The mean (± standard deviation) index percentages of the IgG titers were 74.2 ± 23.6% in the hyperemesis group and 24.3 ± 4.4% in the control group (P < .01, Student t test). Conclusion Infection with H pylori may cause hyperemesis gravidarum.
Obstetrics & Gynecology | 2000
Wolfgang Eppel; Christof Worda; Peter Frigo; Martin Ulm; Elisabeth Kucera; Klaus Czerwenka
Objective To determine the prevalence and association of human papillomavirus (HPV) infection in the cervices and placentas of pregnant women. Methods Cervical samples were taken from 179 of 226 women who had placental biopsies because of abnormal ultrasound findings or were older than 35 years, to detect HPV infections with hybrid capture II tests. Polymerase chain reaction (PCR) was done on placental tissue of 147 of the 226 women to detect HPV DNA. Results We found 44 of 179 women (24.6%, 95% confidence interval 18.3, 31.0) to test positive for HPV in their cervices. Logistic regression analyses showed decreased prevalence of HPV infection with increased maternal age (P = .039). The HPV DNA E6 PCR from the villus tissue was negative in the 147 cases examined. However, a significant contingency coefficient between low-risk HPV infection and elevated risk of chromosome aberration was found (&phis; = V = 0.15, P = .050). Conclusion The infection rate of 24.6% in women without clinical symptoms of HPV infection was high, but there seemed to be no virus transmission to the placenta in women with subclinical infections. Low-risk cervical HPV infection might be associated with a slightly higher risk of abnormal fetal karyotype.
Maturitas | 1997
Michael O. Sator; Elmar A. Joura; Peter Frigo; Christine Kurz; Markus Metka; Anton Hommer; Johannes C. Huber
OBJECTIVES To evaluate the effect of hormone replacement therapy (HRT) on intraocular pressure (IOP) in menopausal women. METHODS The IOP of 25 white menopausal women without an abnormal ophthalmologic history was measured before and during HRT regimen. IOP fluctations were recorded before and 1, 4, and 12 weeks after the beginning of HRT. These measurements were obtained according to a standardized time schedule (08:00, 12:00, 16:00, and 19:00 h). RESULTS The mean IOP in the left eye decreased from 16.2 +/- 2.4 mmHg before therapy to 14.0 +/- 2.1 mmHg after 12 weeks of therapy (P < 0.001). In the right eye, whose IOP was at 15.3 +/- 2.3 mmHg before therapy there was a decrease to 14.0 +/- 1.9 mmHg after 12 weeks of therapy (P < 0.001). CONCLUSION Hormone replacement therapy has a positive effect on IOP in menopausal women.
British Journal of Obstetrics and Gynaecology | 1998
Michael O. Sator; Elmar A. Joura; T. Golaszewski; Doris M. Gruber; Peter Frigo; Markus Metka; Anton Hommer; Johannes C. Huber
Objective To investigate the effect of 17β‐oestradiol ophthalmic drops in comparison with a traditional
Acta Obstetricia et Gynecologica Scandinavica | 2000
Wolfgang Eppel; Christof Worda; Peter Frigo; Mamood Manavi; Klaus Czerwenka
Background. Several epidemiological investigations have shown that cigarette smoking leads to increased serum IL‐6 levels and is a risk factor for cervical cancer.
Maturitas | 1995
Peter Frigo; W. Eppel; Ella Asseryanis; Michael O. Sator; T. Golaszewski; Doris M. Gruber; Christine Lang; Johannes C. Huber
The aim of our study was to examine the effects of hormone replacement on the size of the uterus and the development or increase of myomatas. Fifty perimenopausal women were included in the study (53.8 +/- 5.0 years). Patients received a substitution therapy composed of a combination of 4 mg estradiovalerate and 200 mg prasteronenantate (Gynodian Depot cartridges) given as a muscular injection in 6-10 week intervals (mean 7 weeks +/- 4 days). Prior to the onset of therapy with Gynodian and after a period of 12 months (+/- 13 days) vaginosonography was performed. Measurements taken were length, thickness, height of endometrium, size of ovaries and of myomas. Data obtained were correlated with baseline findings. Within 1 year, significant increases in uterus length from 73.4 mm to 88.2 mm, in uterus thickness from 33.9 mm to 43.5 mm and in endometrium height from 4.1 mm to 6.7 mm were observed (median values). There was an increase in both the number (from 2.2 to 3.5) and the size of the myomatas (29.4-35.0 mm diameter). A statistical analysis conducted by means of the Wilcoxon matched pairs signed-rank sum test showed P < 0.001. No significant change occurred in the size of the ovaries. Our study shows that hormone substitution may have an impact on uterus growth and that therefore vaginosonographical monitoring can be recommended.
Prenatal Diagnosis | 1997
Martin Ulm; Dieter Bettelheim; Barbara Ulm; Peter Frigo; G. Bernaschek
Several clinical investigations on the course and outcome of pregnancies following cordocentesis have mentioned the occurrence of fetal bradycardia at the time of umbilical cord puncture. The prognostic impact of this common complication has remained controversial. Our purpose was to investigate the prevalence and the short‐term and long‐term consequences of fetal bradycardia associated with cordocentesis. This study included all 339 cordocenteses performed in 290 fetuses at the Division of Prenatal Diagnosis and Therapy, University of Vienna, between 1991 and 1994. Clinically significant bradycardia was defined as a drop in the heart rate to less than 100 beats/min for a period of ≥60 s. Bradycardia during or immediately after cordocentesis was observed in 13 cases (3.8 per cent). The fetal/neonatal loss rate per procedure was 61.5 per cent (8/13) in cases with bradycardia and 3.1 per cent (10/326) in those without bradycardia (P<0. 001). Early gestational age and hydrops fetalis correlated significantly with the development of bradycardia at cordocentesis. The other risk groups, including fetuses with intrauterine growth retardation, the puncture site, and the number of puncture attempts did not correlate with fetal bradycardia. Our results indicate that prolonged fetal bradycardia during or after cordocentesis is characteristic of a group of fetuses with an especially unfavourable prognosis.
Gynecologic and Obstetric Investigation | 2000
Wolfgang Eppel; Peter Frigo; Christof Worda; Dieter Bettelheim
In a prospective, randomized study, Bartholin’s cysts were depicted in 36 patients by means of ultrasound imaging. Patients were requested to return for a follow-up US examination after surgery. We were able to show that Bartholin’s cysts can easily be expressed with ultrasonographic techniques. In clinical practice, this approach may not only help to improve diagnostics, but may also make therapy measurable and, for the first time, objectifiable.
Gynecologic and Obstetric Investigation | 1995
Peter Frigo; Wolfgang Eppel; Andrea Frank; Martin Ulm; T. Golaszewski; W. Gruber
A 29-year-old woman presented with preterm labour at 32 weeks of gestation. Tocolytic treatment was started with intravenous hexoprenaline. Twenty-four hours after initiation of treatment, the patient developed supraventricular tachycardia, resistant to digoxin and verapamil. Medical treatment with metoprolol finally restored sinus rhythm. We observed no adverse effects on the fetal heart rate nor on the umbilical cord blood flow.
American Journal of Obstetrics and Gynecology | 1995
Ella Asseryanis; Peter Frigo; Brigitte Schurz; Johannes C. Huber
Abstract We describe for the first time the use of a new ultrasonographic technique of low invasiveness for direct assessment of ectopic pregnancy.