Phebe K. Thompson

THE EFFECT OF POSTURE UPON THE COMPOSITION AND VOLUME OF THE BLOOD IN MAN.

About one year ago, Lindhard (2) reported a few observations on the distribution in the blood stream of vital red injected intravenously. He found that in man, in the sitting position, after a mixing time of 5 minutes, blood from the saphenous vein contained dye in a concentration one-half of that in blood taken from the cubital vein. If, however, the man walked between the time of dye injection and the time of blood collection, the concentration of dye in blood from the two veins was the same. He concluded that, in order to get accurate observations of plasma volume, the subject should walk between the time of dye injection and blood collection. Numerous observations of plasma volume had previously been madeby one of us (3) (42) by means of the so-called dye method, in which a similar dye, brilliant vital red, was used. These had already led to the conclusion that, when observations are made exclusively upon blood from an arm vein in a normal man in the horizontal position after a rest period of at least 30 minutes, similar results are always obtained. The contrast between Lindhards observations and our own made it appear desirable to determine conclusively the effect of posture on plasma volume determinations by the dye method. Early in our work, we observed that in an individual in the standing still position, the volume of cells per liter of blood, the red count and

Fallacies and Dangers in the Treatment of Exophthalmic Goiter by Iodine

Excerpt Until about ten years ago, the treatment of exophthalmic goiter by iodine was considered a dangerous procedure, although it was not claimed that its immediate effects were always harmful. T...