Pier Giuseppe Ciattini

Palladium catalyzed triethylammonium formate reduction of aryl triflates. A selective method for the deoxygenation of phenols.

Abstract Phenols can be selectively deoxygenated by reduction of the corresponding aryl triflates with triethylammonium formate in the presence of a homogeneous palladium catalyst.

Palladium-catalyzed carbonylation of aryl triplates. Synthesis of arenecarboxylic acid derivatives from phenols

Abstract Various aryl triflates derived from phenols were converted into aryl esters or amides in good yields by a palladium-catalyzed reaction with carbon monoxide and alcohols or amines.

A new, palladium-catalyzed synthesis of aromatic mercapturic acid derivatives

Abstract N -Acetyl-L-cysteine methyl ester ( 1 ) reacts under mild conditions with aryl iodides 2 in the presence of a palladium catalyst prepared in situ from Pd 2 dba 3 and dppf to give S -aryl derivatives 3 in moderate to good yields.

Palladium-catalyzed cross-coupling reactions of vinyl and aryl triflates with tetraarylborates

Abstract Sodiumm tetraarylborates 2 have been found to couple efficiently with vinyl and aryl triflates 1 in the presence of a palladium(0) catalyst to afford arylalkenes and biaryls 3 in good yields and under mild conditions.

An efficient synthesis of 3-substituted indoles by palladium-catalyzed coupling reaction of 3-tributylstannylindoles with organic triflates and halides

Abstract The palladium-catalyzed reaction of 1-tosyl-3-tributylstannylindoles 2 with a variety of vinyl, aryl, and heteroaryl triflates and halides ( 1 ) provides a general and efficient method for the synthesis of 3-substituted indoles 3 .

Preparative and regiochemical aspects of the palladium-catalyzed carbonylative coupling of 2-hydroxyaryl lodides with ethynylarenes

Abstract The title reaction has been conveniently carried out in DMF at 60°C under 1 atm of CO pressure using DBU as the base and Pd(OAc)2(DPPF)2 as the catalyst to afford generally mixtures of flavones 4 and aurones 5 in varying yields, depending on the substituents in the both reactants. Factors controlling the regioselectivity for 4 or 5 formation in this and in similar, previously reported, coupling procedures have been examined.

Palladium-catalysed vinylation of allylic alcohols with enol triflates. A convenient synthesis of conjugated dienols

Abstract Heck-type reactions involving enol triflates 1 and allylic alcohols 2 result in the formation of conjugated dienols as the major products. The regioselectivity for substitution at the terminal carbon of the alcohol is generally good and dienols 3 can be isolated in synthetically useful yields.

A concise, palladium-catalyzed approach to (±)-lysergic acid

A new and straightforward route to (±)-lysergic acid (1) from the tricyclic ketone 2 is described involving the palladium-catalyzed coupling of the vinyl triflate 3 with the olefin 15 as the key step.

A new synthesis of 3-ylidenephthalides via palladium-catalyzed cyclocarbonylation of 2-triflyloxyacetophenones

Abstract The reaction of 2-triflyloxyacetophenone derivatives 1 with carbon monoxide in the presence of a palladium catalyst affords 3-ylidenephthalides 2 in good yields and under mild conditions.

A new pathway to alkynyl ketones via palladium-catalyzed carbonylative coupling of vinyl triflates with 1-alkynes

Abstract The palladium-catalyzed coupling reaction of vinyl triflates with 1-alkynes in the presence of carbon monoxide takes place under mild conditions to produce 1-alken-4-yn-3-ones in moderate to good yields.