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Pierre Broto

Aventis Pharma

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Publication

Featured researches published by Pierre Broto.

Journal of Medicinal Chemistry | 2002

SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design: Application to the Discovery of Nanomolar Inhibitors of Src SH2

Dominique Lesuisse; Gudrun Lange; Pierre Deprez; Didier Benard; Bernard Schoot; Georges Delettre; Jean-Pierre Marquette; Pierre Broto; Véronique Jean-Baptiste; Paulette Bichet; Edoardo Sarubbi; Eliane Mandine

Journal of Medicinal Chemistry | 2003

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.

Gudrun Lange; Dominique Lesuisse; Pierre Deprez; Bernard Schoot; Petra Loenze; Didier Benard; Jean-Pierre Marquette; Pierre Broto; Edoardo Sarubbi; Eliane Mandine

Journal of Medicinal Chemistry | 2002

Principles governing the binding of a class of non-peptidic inhibitors to the SH2 domain of src studied by X-ray analysis

Gudrun Lange; Dominique Lesuisse; Pierre Deprez; Bernard Schoot; Petra Loenze; Didier Benard; Jean-Pierre Marquette; Pierre Broto; Edoardo Sarubbi; Eliane Mandine

Archive | 2004

Hexahydropyridazine-3-carboxylic acid hydrazide and hydrazone derivatives, combinatorial libraries containing same, pharmaceutical compositions containing same and methods of preparation

Neerja Bhatnagar; Pierre Broto; Jean-Francois Gourvest; Jacques Mauger

Archive | 2006

DERIVADOS DE PIRIDAZINA, SUA UTILIZACAO COMO MEDICAMENTOS E SEU PROCESSO DE PREPARACAO

Bhatnagar Neerja; Didier Benard; Pierre Broto; Gourvest Jean-Francois; Jacques Mauger

Archive | 2003

Pyridazinderivate, deren verwendung als heilmittel, und deren verfahren zu ihrer verwendung Pyridazine derivatives, their use as therapeutic agents, and their methods for their use

Didier Benard; Neerja Bhatnagar; Pierre Broto; Jean-Francois Gourvest; Jacques Mauger

Archive | 2003

Pyridazine derivatives, their use as a remedy, and their methods for their use

Didier Benard; Neerja Bhatnagar; Pierre Broto; Jean-Francois Gourvest; Jacques Mauger

Archive | 2003

Pyridazinderivate, deren verwendung als heilmittel, und deren verfahren zu ihrer verwendung Pyridazine derivatives, whose use as a remedy, and their methods for their use

Neerja Bhatnagar; Didier Benard; Pierre Broto; Jean-Francois Gourvest; Jacques Mauger

Archive | 2003

Novel hexahydro-pyridazine-3-carbocylic acid hydrazide or hydrazone derivatives, combinatorial libraries containing same, use thereof as medicines, pharmaceutical compositions containing same and methods for preparing same

Neerja Bhatnagar; Pierre Broto; Jean-Francois Gourvest; Jacques Mauger

Archive | 2003

PYRIDAZINE DERIVATIVES, USE OF THE SAME AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING THE SAME

Neerja Bhatnagar; Didier Benard; Pierre Broto; Jean-Francois Gourvest; Jacques Mauger

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Collaboration

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Didier Benard

Aventis Pharma

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Jacques Mauger

Aventis Pharma

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Neerja Bhatnagar

Aventis Pharma

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Jean-Francois Gourvest

Aventis Pharma

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Bernard Schoot

Aventis Pharma

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Eliane Mandine

Aventis Pharma

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Gudrun Lange

Bayer

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Gourvest Jean-Francois

Aventis Pharma

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Jean Francois Gourvest

Genentech

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