Purushotham Vemishetti

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Featured researches published by Purushotham Vemishetti.

Tetrahedron Letters | 1996

A simple, rapid and efficient protocol for the selective phosphorylation of phenols with dibenzyl phosphite☆

Lee J. Silverberg; John L. Dillon; Purushotham Vemishetti

Abstract Phosphorylation of phenols with dibenzyl phosphite, carbon tetrachloride, N , N -diisopropylethylamine, and catalytic DMAP in acetonitrile at −10°C is rapid, mild, clean, high yielding, and selective.

Tetrahedron Letters | 1994

A practical synthesis of (S)-HPMPC

Paul R. Brodfuehrer; Henry G. Howell; Chester Sapino; Purushotham Vemishetti

Abstract Synthesis of the title nucleotide was accomplished in high yield starting from (S)-tritylglycidol ( 5 ) and N-benzoylcytosine ( 9 ).

Synthetic Communications | 1995

A Short Synthesis of d-Sotalol

Patrick Smith; Paul R. Brodfuehrer; John L. Dillon; Purushotham Vemishetti

Abstract Asymmetric synthesis of d-Sotalol (2) was accomplished by chiral homogenous hydrogenation of (4-isopropylaminoacetyl)methane-sulfonanilide hydrochloride (1).

Archive | 1993

N-substituted 2-azetidinones

Allan W. Rey; Purushotham Vemishetti; Roberto Droghini

Organic Process Research & Development | 2009

The Process Development of Ravuconazole: An Efficient Multikilogram Scale Preparation of an Antifungal Agent(1)

Jaan A. Pesti; Chien-Kuang Chen; Lori Spangler; Albert J. DelMonte; Serge Benoit; Derek Berglund; Jeffrey T. Bien; Paul R. Brodfuehrer; Yeung Y. Chan; Elisabeth Corbett; Carrie A. Costello; Paul Demena; Robert P. Discordia; Wendel W. Doubleday; Zhinong Gao; Stephane Gingras; John Anthony Grosso; Oscar W. Haas; David Kacsur; Chiajen Lai; Simon Leung; Melanie Miller; Jale Muslehiddinoglu; Nina Nguyen; Jun Qiu; Martina Olzog; Emily A. Reiff; Dominique Thoraval; Michael J. Totleben; Dale Vanyo

Archive | 2005

Process for the preparation of entecavir and novel intermediates thereof via carbon-silicon oxidation

Maotang X. Zhou; Emily A. Reiff; Purushotham Vemishetti; Yadagiri Pendri; Ambarish K. Singh; Siva Josyula Prasad; Ulhas P. Dhokte; Xinhua Qian; Pia Mountford; Kerry B. Hartung; Helen Sailes

Organic Process Research & Development | 1997