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Yadagiri Pendri

Bristol-Myers Squibb

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Publication

Featured researches published by Yadagiri Pendri.

Bioorganic & Medicinal Chemistry Letters | 2002

The synthesis and characterization of BMS-204352 (MaxiPost) and related 3-fluorooxindoles as openers of maxi-K potassium channels

Piyasena Hewawasam; Valentin K. Gribkoff; Yadagiri Pendri; Steven I. Dworetzky; Nicholas A. Meanwell; Eduardo J. Martinez; Christopher G. Boissard; Debra J. Post-Munson; Joanne T. Trojnacki; Krishnaswamy Yeleswaram; Lorraine Pajor; Jay O. Knipe; Qi Gao; Robert Kevin Perrone; John E. Starrett

3-Aryl-3-fluorooxindoles can be efficiently synthesized in two steps by the addition of an aryl Grignard to an isatin, followed by treatment with DAST. Oxindole 1 (BMS-204352; MaxiPost) can be isolated using chiral HPLC or prepared by employing chiral resolution. Cloned maxi-K channels are opened by 1, which demonstrates a brain/plasma ratio >9 in rats.

Tetrahedron-asymmetry | 2006

Preparation of a chiral synthon for an HBV inhibitor: enzymatic asymmetric hydrolysis of (1α,2β,3α)-2-(benzyloxymethyl)cyclopent-4-ene-1,3-diol diacetate and enzymatic asymmetric acetylation of (1α,2β,3α)-2-(benzyloxymethyl)cyclopent-4-ene-1,3-diol

Ramesh N. Patel; Amit Banerjee; Yadagiri Pendri; Jing Liang; Chung-Pin Chen; Richard H. Mueller

Archive | 2005

Process for the preparation of entecavir and novel intermediates thereof via carbon-silicon oxidation

Maotang X. Zhou; Emily A. Reiff; Purushotham Vemishetti; Yadagiri Pendri; Ambarish K. Singh; Siva Josyula Prasad; Ulhas P. Dhokte; Xinhua Qian; Pia Mountford; Kerry B. Hartung; Helen Sailes

Archive | 1995

Method for preparing thioether conjugates

John K. Thottathil; Yadagiri Pendri; Kumar G. Gadamasetti; Wen-Sen Li; Richard H. Mueller

Archive | 2001

Process for water soluble azole compounds

Chung-Pin Chen; Timothy P. Connolly; Laxma Reddy Kolla; John D. Matiskella; Richard H. Mueller; Yadagiri Pendri; Dejah T. Petsch

Archive | 2000

Methods for the preparation of biphenyl isoxazole sulfonamides

Richard Polniaszek; Xuebao Wang; Jeffrey S. DePue; Chennagiri R. Pandit; Kumar G. Gadamasetti; Yadagiri Pendri; Eduardo J. Martinez

Journal of Labelled Compounds and Radiopharmaceuticals | 2005

Synthesis of [14C]‐radiolabelled entecavir

Marc Ogan; David J. Kucera; Yadagiri Pendri; J. Kent Rinehart

Archive | 1998

Preparation of 3-fluoro oxindole derivatives

Yadagiri Pendri; Eduardo J. Martinez; John K. Thottathil; Piyasena Hewawasam

Archive | 1995

Method for preparing homochiral maleimide intermediates, via silylation techniques, used in the enantioselective preparation of anti-thrombotic and anti-vasospastic compounds

Michael Humora; Richard H. Mueller; Janak Singh; Yadagiri Pendri

Archive | 1994

Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds

John K. Thottathil; Yadagiri Pendri; Wen-Sen Li; John J. Venit; San Kiang; Robert Waltermire

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John K. Thottathil

Princeton University

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Richard Polniaszek

Bristol-Myers Squibb

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Ambarish K. Singh

Bristol-Myers Squibb

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Siva Josyula Prasad

Bristol-Myers Squibb

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Jing Liang

Bristol-Myers Squibb

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Purushotham Vemishetti

Bristol-Myers Squibb

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Richard H. Mueller

Bristol-Myers Squibb

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David R. Kronenthal

Bristol-Myers Squibb

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Gerald L. Powers

Bristol-Myers Squibb

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Jeffrey M. Evans

Bristol-Myers Squibb

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