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Featured researches published by R. Horie.


European Journal of Pharmacology | 1980

The hypotensive effect of centrally administered tyrosine

Yukio Yamori; Michihiro Fujiwara; R. Horie; Walter Lovenberg

Intraventricular injection of 15 microgram L-tyrosine results in a significant reduction in blood pressure in the spontaneously hypertensive rat. An increase in the turnover of norepinephrine as indexed by MOPEG-SO4 is observed concurrently. The data are consistent with the previously suggested depressor role of certain central noradrenergic neurons.


Atherosclerosis | 1982

Myocardial-ischemic rats (MIR): Coronary vascular alteration induced by a lipid-rich diet☆

Yukio Yamori; Masako Kihara; Y. Nara; R. Horie

Abstract A new strain of rats in which there is a high incidence of heart failure (myocardial -ischemic rats: MIR) has been inbred in our laboratory from a substrain of stroke-prone spontaneously hypertensive rats (SPSHR). The clinicopathological manifestations of MIR on a high-fat-cholesterol diet (HFCD) were found to be similar to those seen in ischemic heart disease (IHD) in man, in terms of vectorcardiographical (VCGcal) alterations, coronary fat deposition, thrombosis and resultant myocardial fibrosis. MIR should serve as a good experimental model of IHD.


Japanese Heart Journal | 1980

Synaptosomal Membrane Characteristics in Stroke-prone SHR (SHRSP), Stroke-resistant SHR (SHRSR) and Wistar-Kyoto Rats (WKY)

Y. Nara; Yukio Yamori; R. Horie; Masahiro Kihara; Akira Ooshima; Walter Lovenberg


Japanese Heart Journal | 1979

Hypertension and atherogenesis in animal models - a new aspect on the relationship [proceedings].

Yukio Yamori; Nobuko Iritani; Y. Nara; R. Horie; Michiya Ohtaka; Akira Ooshima


Japanese Heart Journal | 1984

STUDIES ON PREVENTION OF STROKE IN STROKE-PRONE SHR (SHRSP) 8) EFFECT OF UREA-CONTAINING DIET AND ITS MECHANISM

Katumi Ikeda; H. Wang; Y. Nara; Masahiro Kihara; R. Horie; Yukio Yamori


Japanese Heart Journal | 1983

SODIUM METABOLISM IN SHR AND WKY ON VARIOUS DIETS

H. Wang; Katumi Ikeda; Masahiro Kihara; Y. Nara; R. Horie; Yukio Yamori


Japanese Heart Journal | 1981

Behavioral Characteristics of Stroke-Prone SHR

L.A. Rothblat; R. Horie; Masahiro Kihara; Yukio Yamori; H. Tanase; Michihiro Fujiwara; Walter Lovenberg


Japanese Heart Journal | 1981

Effect of Cervical Sympathectomy on the Incidence of Stroke in Stroke-Prone SHR

Yukio Yamori; R. Horie; H. Tanase; Masahiro Kihara; Walter Lovenberg


Japanese Heart Journal | 1981

Role of Central Phenyl Ethanolamine N-Methyltransferase Activity in Blood Pressure Regulation in SHR

Yukio Yamori; Michihiro Fujiwara; H. Tanase; R. Horie; Walter Lovenberg


Japanese Heart Journal | 1981

Genetical Disposition to Cardiac Hypertrophy in Rats

H. Tanase; R. Horie; Masahiro Kihara; Yukio Yamori; Walter Lovenberg

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Yukio Yamori

Mukogawa Women's University

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Walter Lovenberg

National Institutes of Health

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Y. Nara

National Institutes of Health

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Masahiro Kihara

New York Academy of Medicine

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H. Tanase

National Institutes of Health

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Michihiro Fujiwara

National Institutes of Health

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Yukio Yamori

Mukogawa Women's University

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