Rafael Celestino Souza

A swirler stabilized combustion chamber for a micro-gas turbine fuelled with natural gas

Micro-gas turbines are a good alternative for on-site power generation, since their operation is very reliable. The possibility of operating with various fuels increases versatility and, as a result, the usage of these devices. Focusing on a performance improvement of a tri-fuel low-cost micro-gas turbine, this work presents investigations of the inner flow of its combustion chamber. The aim of this analysis was the characterization of the flame structure by the temperature field of the chamber inner flow. The chamber was fuelled with natural gas. In the current chamber, a swirler and a reversed flow configuration were utilized to provide flame stabilization. The inner flow investigations were done with numerical analysis, which were compared to experimental data. The analysis of the inner flow was done with numerical simulations, which used the RSM turbulence model. A β-PDF equilibrium model was adopted to account for the turbulent combustion process. Different models of heat transfer were compared. Thermal radiation and specially heat conduction in the liner walls played significant roles on results.

Oral health status of children and young adults with autism spectrum disorders: systematic review and meta‐analysis

BACKGROUND Individuals with special needs are often affected by oral disorders such as dental caries and periodontal disease. Current data regarding prevalence of these conditions in individuals with autism spectrum disorders (ASD) are controversial. AIM To conduct a systematic review and meta-analysis to verify the prevalence of dental caries and periodontal disease in individuals with ASD, especially children and young adults. DESIGN Searches were conducted through MEDLINE/PubMed, Web of Science, and Scopus databases in December 2015. Studies were included if fulfilled the following eligibility criteria: to evaluate the oral health status of individuals with ASD; to be an observational study; and to assess the prevalence of dental caries and/or periodontal disease. Meta-analyses were conducted considering prevalence of dental caries and periodontal disease in individuals as outcome. RESULTS Search strategy identified 928 potentially relevant articles and seven of them were included in this review. All included studies reported dental caries prevalence, and the pooled prevalence was 60.6% (95% CI: 44.0-75.1). Moreover, only three studies showed prevalence of periodontal disease, resulting in pooled prevalence of 69.4% (95% CI: 47.6-85.0). CONCLUSION Prevalence of dental caries and periodontal disease in children and young adults with ASD can be considered as high, pointing to the need for oral health policies focused on these individuals.

ESTUDO DO METABOLOMA DE BIOFLUIDOS EM PACIENTES PEDIÁTRICOS NEFROPATAS E SUA ASSOCIAÇÃO COM A DOENÇA PERIODONTAL.

INTRODUCAO: Metabolomica e a tecnica que analisa metabolitos endogenos e exogenos de baixa massa molecular encontrados em biofluidos e tecidos. Diversos estudos tem mostrado a importância da saude bucal em pacientes com doenca renal cronica (DRC). OBJETIVO: Identificar e interpretar a funcao de metabolitos salivares e de urina de pacientes com DRC e sua possivel associacao com a doenca periodontal (DP). METODOS: 30 adolescentes e adultos jovens com DRC, 12-18 anos, cadastrados no CAPE /FOUSP e no ICrFMUSP, fizeram parte deste estudo. O grupo controle foi composto por 30 individuos clinicamente saudaveis. Os especimes clinicos foram coletados e armazenados a -80°C ate a realizacao da analise de cromatografia gasosa acoplada ao espectrometro de massa (GC-MS). no laboratorio Dempster da EPUSP. A analise periodontal foi realizada por meio do indice de higiene oral simplificado (OHI-S), sangramento a sondagem e profundidade de sondagem. RESULTADOS: As analises estatisticas foram realizadas por meio da analise de componentes principais (PCA), testes de Mann-Whitney e Kruskal-Wallis. A quantificacao relativa de cada metabolito mostrou maiores concentracoes entre pacientes com DRC sem DP e com DRC e com DP, de alanina (p<0.0001), glicina (p<0.0001), tirosina (p=0.021),serina (p<0.0001),prolina (p<0.0002),leucina (p<0.0003), citrulina (p<0.0001), arginina (p<0.0002), p-Cresol(p<0.0003) e acetofenona (p<0.0003). Grupos com DRC mostraram concentracoes alteradas de acidos carboxilicos e dimetilarginina. CONCLUSOES: Ambas as patologias estimulam o processo oxidativo sintetizando metabolitos que podem potencializar a severidade da DRC. Verificamos que, apesar do perfil metabolico ser diferente, alguns metabolitos sao compartilhados por todos os grupos.

Initial approach in cleidocranial dysplasia: the role of Pediatric Dentistry

Objective: to emphasize the importance of Pediatric Dentistry in the dental treatment planning as a first step of rehabilitation in a pediatric patient diagnosed with Cleidocranial Dysplasia (CCD). Case Report: this study presents the case of a ten years old girl, with CCD diagnosis, which attended the Sector of Pediatric Dentistry of São Leopoldo Mandic School of Dentistry Campinas / São Paulo sent by orthopedist, your main complaint was the delay on superior anterior teeth irruption. Needs preventive, curative, rehabilitative, orthodontic and surgical dental treatment. After an interdisciplinary planning, a treatment proposal was nominated and accepted by responsibles’ patient.

Identification of microorganisms in biofluids of individuals with periodontitis and chronic kidney disease using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

RATIONALE Chronic kidney disease (CKD) and periodontitis (PD) are important health issues. There is a large variety of microorganisms related to the pathogenesis of periodontitis, and optimising the time and the cost of laboratory assays to detect these organisms is highly valuable in the medical field. METHODS Bacteria were isolated from saliva and oral biofilm of 30 adolescents and young adults with definite medical and dental diagnosis of CKD and PD, respectively, and proteins were extracted for microorganism identification by means of the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) technique. RESULTS The results showed that the most incident microorganisms were Actinomyces dentalis (43%), Acinetobacter ursingi (60%), Aggregatibacter actinomycetencomitans (60%), Corynebacterium argentoctens (63%), Staphylococcus aureus (93%), Streptococcus salivarius (97%) and Tannerella forsythensis (43%). The analysis of oral biofilm showed higher incidences for Actinomyces dentalis (33%), Acinetobacter ursingi (50%), Aggregatibacter actinomycetencomitans (50%), Corynebacterium argentoctens (70%), Pseudomonas aeruginosa (40%), Staphylococcus aureus (73%) and Streptococcus salivarius (87%). CONCLUSIONS Based on these results, we concluded that the MALDI Biotyper protocol proves useful as a rapid and reliable assay for distinguishing different microorganisms possibly related to CKD and PD. Copyright