Rajenahally S. Narasegowda

Nipecotic acid hydrochloride

The title compound (3-carboxypiperidinium chloride), C6H12NO2+.Cl-, is the hydrochloride of nipecotic acid and is used as a drug intermediate and in the synthesis of gamma-aminobutyric acid (GABA) uptake inhibitors. The geometric parameters are in the normal ranges. The crystal packing is stabilized by O-H...Cl and N-H...Cl hydrogen bonds.

C—halogen⋯π dimer and C—H⋯π interactions in 1-(2-bromo-4,5-di­meth­oxy­benzyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde and 2-butyl-4-chloro-1-(6-methyl-1,3-benzodioxol-5-ylmethyl)-1H-imidazole-5-carbaldehyde

The structures of the title compounds, C17H20BrClN2O3, (I), and C17H19ClN2O3, (II), are stabilized by intramolecular C-H...O and C-H...pi interactions. The stability of the molecular packing in (I) and (II) arises from a diverse set of weak intermolecular C-H...O, C-H...pi and C-halogen...pi interactions. In the crystal structure of (I), molecules aggregate in dimeric subunits via C-Br...pi interactions. The dimers are interlinked by C-H...O hydrogen bonds. The halogens cluster together and form a channel along the b axis. In (II), the packing is mainly governed by intermolecular C-H...O and C-H...pi interactions.

2,2 `-Diaminodibenzyl: a rare case of crystallographically non-compliant molecular symmetry

The title compound,

Conformations of three heterocyclic perhydro­pyrrolobenzofurans and polymeric assembly via co-operative inter­molecular C—H⋯O hydrogen bonds

C_{14}H_{16}N_2

5-4 `-(Bromomethyl)biphenyl-2-yl]-2-trityl-2H-tetrazole

, adopts a trans-planar conformation. However, the molecule, which possesses

N—H+⋯Cl− and C—H⋯O interactions in 6-fluoro-3-(4-piperidinio)benz[d]isoxazole chloride

C_i

4 `-(2-Butyl-4-chloro-5-formylimidazol-1-ylmethyl)-biphenyl-2-carbonitrile

point group symmetry, crystallizes in the non-centrosymmetric space group

4 `-Methylbiphenyl-2-carboxylic acid

P2_{1}2_{1}2_{1}

N-amino-3-methyl-2,3-dihydro-1,3-benzothiazoliminium chloride monohydrate

. In the crystal structure, the molecular symmetry is only approximately retained. The crystal packing is predominantly stabilized by

4′-[2-Butyl-4-chloro-5-(hydroxy­imino­methyl)-1H-imidazol-3-yl­methyl]­bi­phenyl-2-carbo­nitrile

N-H{\cdot\cdot\cdot}N