Santhosh L. Gaonkar

5-4 `-(Bromomethyl)biphenyl-2-yl]-2-trityl-2H-tetrazole

The title compound, C33H25BrN4, belongs to the class of substituted tetrazoles. This type of compound is an important starting material for the synthesis of pharmaceutically active materials.

1-(3-Bromo-2-thien-yl)ethanone.

In the title compound, C6H5BrOS, the non-H and aromatic H atoms lie on a crystallographic mirror plane. In the crystal, molecules are linked into chains propagating along the c axis by intermolecular C—H⋯O hydrogen bonds.

2-(5-ethylpyridin-2-yl)ethanol

The title compound, C9H13NO, is the key intermediate for the synthesis of the antidiabetic drug pioglitazone and it is used as a versatile intermediate in the synthesis of a number of biologically active novel heterocycles. Both side-chains are located on the same side of the aromatic ring. The molecules are connected by O-H...N hydrogen bonds into ribbons which show a herring-bone-like pattern.

5-Amino-3H-isobenzofuran-1-one (5-aminophthalide).

The title compd., C8H7NO2, serves as an intermediate for the synthesis of citalopram. Crystallog. data are given. The packing of the planar mols. is stabilized by N-H···O and N-H···N H bonds. [on SciFinder(R)]

3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione.

The title compd., C10H8N2O4S, serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. Crystallog. data are given. The nearly planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring. [on SciFinder(R)]