Ralph Bogart

Alteration of Activity of Thyroid Gland of Beef Cattle with Testosterone.

Summary and Conclusions 1. Testosterone injected intramuscularly at the rate 1 mg/kg of body wt per week in beef heifers and steers from 500 to 800 lb live wt had the following effects: a) Increased average daily gain and decreased feed requirements per unit gain, b) Increased weight of the thyroid glands, c) Increased secretory activity of the thyroid gland, d) Decreased stores of thyroxine in the thyroid gland. 2. Correlations between thyroid gland activity and growth rate are suggested as indicating a possible mode of the action of testosterone in affecting growth of beef cattle. 3. A method is described using the time of asphyxiation of thiouracil-treated mice as a measure of thyroxine content of the thyroid gland.

Ascorbic Acid Content of Milk of Various Species as Influenced by Ascorbic Acid Injection and Diet

Summary Values for ascorbic acid in ewe milk, determined periodically over the lactation period, ranged from 25 to 40 mg per quart. The intravenous injection of ascorbic acid resulted in a marked, temporary rise in the vitamin content of the milk of the ewe and cow. A study of 52 samples of mare milk gave values ranging from 2,7 to 11 5 mg per quart. The nature of the feed appeared to be a factor in the wide variations noted. Values obtained on guinea pig milk ranged from 108 to 711 mg per quart. Both chemical and biological evidence was obtained that the ascorbic acid content of the milk of the guinea pig is influenced by the nature of the diet.

Radiation and responses of rabbit ear artery to xylene, alcohol, and epinephrine.

When measured 4 months after 100 R of whole-body X-irradiation, there was no difference between the diameters of ear arteries of irradiated or nonirradiated New Zealand, Flemish Giant, or Polish rabbits. The responses of the ear arteries to xylene, alcohol, and epinephrine were similar in irradiated and nonirradiated rabbits. After 300 R all three breeds responded more slowly than controls to xylene, alcohol, and epinephrine, and the time for reaching a maximal response was longer. However, in the physiologically balanced New Zealands there was no difference in the magnitudes of the responses of the central ear arteries to xylene, alcohol, and epinephrine between irradiated and nonirradiated rabbits. The arteries of the Flemish Giant and Polish, already dilated by 300 R, responded to xylene and alcohol with marked additional dilation beyond the magnitude of the dilation induced in controls. Epinephrine produced more constriction of the central ear artery in the irradiated Flemish Giant and Polish rabbits ...