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Dive into the research topics where Ravindra N. Guthikonda is active.

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Featured researches published by Ravindra N. Guthikonda.


Bioorganic & Medicinal Chemistry Letters | 1995

The synthesis and antibacterial activity of 2-carbolinyl-carbapenems: potent anti-MRSA/MRCNS agents

Laura C. Meurer; Ravindra N. Guthikonda; Joann Huber; Frank P. DiNinno

Abstract A series of 2-carbolinyl-carbapenems was prepared via the Stille stannane coupling reaction. This new class of antibiotics exhibited potent activity in vitro against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase negative staphylococci (MRCNS) as well as a broad spectrum of antibacterial activity. A high resistance to the mammalian dehydropeptidase, DHP-1, was also observed.


Archive | 1995

Cyclic amidine analogs as inhibitors of nitric oxide synthase

Ravindra N. Guthikonda; Stephan K. Grant; Malcolm Maccoss; Shrenik K. Shah; Kothandaraman Shankaran; Charles G. Caldwell; Philippe L. Durette


Archive | 1995

Substituted heterocycles as inhibitors of nitric oxide synthase

Shrenik K. Shah; Stephan K. Grant; Malcolm Maccoss; Kothandaraman Shankaran; Hongbo Qi; Ravindra N. Guthikonda


Archive | 2003

Substituted amides active at the cannabinoid-1 receptor

William K. Hagmann; Linus S. Lin; Shrenik K. Shah; Ravindra N. Guthikonda; Hongbo Qi; Linda L. Chang; Ping Liu; Helen M. Armstrong; James P. Jewell; Thomas J. Lanza


Bioorganic & Medicinal Chemistry Letters | 2004

Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase.

Kothandaraman Shankaran; Karla L. Donnelly; Shrenik K. Shah; Ravindra N. Guthikonda; Malcolm Maccoss; John L. Humes; Stephen Pacholok; Stephan K. Grant; Theresa M. Kelly; Kenny K. Wong


Archive | 1978

6-Amido-3-substituted-amino-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid

Burton G. Christensen; Ravindra N. Guthikonda; Ronald W. Ratcliffe


Bioorganic & Medicinal Chemistry Letters | 2004

Syntheses and SAR studies of 4-(heteroarylpiperdin-1-yl-methyl)-pyrrolidin-1-yl-acetic acid antagonists of the human CCR5 chemokine receptor.

Kothandaraman Shankaran; Karla L. Donnelly; Shrenik K. Shah; Ravindra N. Guthikonda; Malcolm Maccoss; Sander G. Mills; Sandra L. Gould; Lorraine Malkowitz; Salvatore J. Siciliano; Martin S. Springer; Anthony Carella; Gwen Carver; Daria J. Hazuda; Karen Holmes; Joseph Kessler; Janet Lineberger; Michael D. Miller; Emilio A. Emini; William A. Schleif


Bioorganic & Medicinal Chemistry Letters | 2005

Synthesis and evaluation of CCR5 antagonists containing modified 4-piperidinyl-2-phenyl-1-(phenylsulfonylamino)-butane

Shrenik K. Shah; Natalie Chen; Ravindra N. Guthikonda; Sander G. Mills; Lorraine Malkowitz; Martin S. Springer; Sandra L. Gould; Julie A. DeMartino; Anthony Carella; Gwen Carver; Karen Holmes; William A. Schleif; Renee Danzeisen; Daria J. Hazuda; Joseph Kessler; Janet Lineberger; Michael D. Miller; Emilio A. Emini; Malcolm Maccoss


Archive | 1977

6-Amido-1-carba-2-penem-3-carboxylic acid

Lovji D. Cama; Burton G. Christensen; Ravindra N. Guthikonda


Archive | 1993

MRSA active 2-phenyl-carbapenems

Frank P. DiNinno; Ravindra N. Guthikonda

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