Ray C. Wasielewski

Wear patterns on retrieved polyethylene tibial inserts and their relationship to technical considerations during total knee arthroplasty

Fifty-five unconstrained polyethylene tibial inserts were retrieved at revision total knee arthroplasty and examined for evidence of wear after a mean implantation time of 34.2 months (2.5-80 months). Twenty inserts were ultra-high molecular weight polyethylene (UHMWPE) and 35 were carbon-reinforced polyethylene. Topographic maps of the articular and metal-backed surfaces of each component were constructed to characterize the extent and location of polyethylene degradation, identified visually by mode. In 32 of the retrieved inserts, pre- and postarthroplasty or prerevision radiographs were analyzed for component positioning, sizing, and extremity alignment. These factors then were compared with the patterns and severity of polyethylene wear on the inserts to establish correlations. Severe generalized articular wear was seen in inserts with third body wear from patellar metal-backed failure and cement debris. Severe localized delamination wear was seen in inserts with rotational-subluxation patterns of wear (p = 0.05). The external rotation subluxation wear pattern was strongly associated with knees that had lateral subluxation of the patella (p = 0.0002). Articular wear and cold flow into screw holes tended to be greater in the tightest prearthroplasty compartment (medial in the varus knee [p = 0.0157]; lateral in the valgus knees [p = 0.0226]). Fourteen of 16 knees with a preoperative varus deformities--even when corrected to a normal postarthroplasty anatomic axis--still had greater medial compartment articular wear (p = 0.001). Twelve of these knees did not have a medial release at the time of initial arthroplasty. Preoperative varus also was found to be related to the occurrence of posteromedial cold flow of polyethylene into tibial tray screw holes (p = 0.007). Increasing tibial insert posterior slope was associated with increasingly posterior articular wear track location (p = 0.03). This study indicates that unconstrained tibial component wear patterns and severity may be associated with clinical and mechanical factors under the surgeons control, including component size and position, and knee alignment and ligament balance.

Acetabular anatomy and the transacetabular fixation of screws in total hip arthroplasty.

An anatomical and radiographic study was undertaken to determine the safest zones in the acetabulum for the transacetabular placement of screws during uncemented acetabular arthroplasty. To avoid injury to intrapelvic structures, which are not visible to the surgeon during placement of the screws, cadavera were studied to define the location of these structures with respect to fixed points of reference within the acetabulum. Four clinically useful acetabular quadrants were delineated. The quadrants are formed by drawing a line from the anterior superior iliac spine through the center of the acetabulum to the posterior fovea, forming acetabular halves. A second line is then drawn perpendicular to the first at the mid-point of the acetabulum, forming four quadrants. The posterior superior and posterior inferior acetabular quadrants contain the best available bone stock and are relatively safe for the transacetabular placement of screws. The anterior superior and anterior inferior quandrants should be avoided whenever possible, because screws placed improperly in these quadrants may endanger the external iliac artery and vein, as well as the obturator nerve, artery, and vein. The acetabular-quadrant system provides the surgeon with a simple intraoperative guide to the safe transacetabular placement of screws during primary and revision acetabular arthroplasty.

Tibial insert undersurface as a contributing source of polyethylene wear debris.

Sixty-seven ultrahigh molecular weight polyethylene tibial inserts from cementless total knee arthroplasties were retrieved at autopsy and revision surgery and analyzed for evidence of articular and nonarticular surface wear after a mean implantation time of 62.8 months (range, 4-131 months). Polyethylene cold flow and abrasive wear on the nonarticular insert surface (undersurface) were assigned a wear severity score (Grade 0-4). The severity of articular wear was assessed quantitatively and graded. Corresponding prerevision radiographs were evaluated for evidence of tibial metaphyseal osteolysis and osteolysis around tibial fixation screws. Exact nonparametric conditional inference methods were used to establish correlations between different variables and the occurrence of tibial metaphyseal osteolysis. Severe Grade 4 wear of the tibial insert undersurface was associated with tibial metaphyseal osteolysis or osteolysis around fixation screws. Time in situ statistically was related to Grade 4 undersurface wear and tibial metaphyseal osteolysis. The occurrence of tibial osteolysis was not related statistically to articular wear severity, insert thickness, or implant type. The main articulation between the femoral implant and ultrahigh molecular weight polyethylene insert has been assumed to be the primary source of polyethylene debris contributing to osteolysis and total knee arthroplasty implant failure. The undersurface of the insert is an additional source of polyethylene debris contributing to tibial metaphyseal osteolysis. To lessen polyethylene debris produced at this modular interface, the tibial implant locking mechanism should fix the insert firmly to the metal backing to decrease relative micromotion. Because motion between the insert and metal backing may be inevitable, the wear characteristics of the inner tray surface should be optimized to minimize wear debris production at this other articulation.

Patient comorbidity : relationship to outcomes of total knee arthroplasty

One hundred six patients treated consecutively with total knee arthroplasty were evaluated to determine whether preoperative comorbidity (as measured by patient class, knee score, short form, anesthesia severity assessment, and number of medical comorbidities) correlated with perioperative and postoperative outcomes, including length of stay, total (and specific) hospital charges, and validated outcome scores. The length of stay for total knee arthroplasty was longer in patients who had lower preoperative knee scores and for patients with greater medical and musculoskeletal morbidity. Greater total hospital costs were associated with Class C patients and patients with poor anesthesia morbidity ratings. Patients who were debilitated medically and had four or more risk factors had decreased postoperative outcome scores. Preoperative medical and musculoskeletal morbidity influence the results of total knee arthroplasty. These findings may be useful to surgeons for optimizing resource utilization and outcomes in patients undergoing total knee arthroplasty. These data must be accounted for when contrasting total knee arthroplasty results between different surgeons and institutions.

Results of different surgical procedures on total knee arthroplasty infections

Seventy-six consecutive infected total knee arthroplasties in 74 patients were treated between December 1981 and March 1990. The average follow-up period was 57 months (range, 24-121 months). No patients were lost to follow-up evaluation and 12 patients died from unrelated causes. Patients were classified, based on the duration of their symptoms prior to treatment, as acutely infected (< 2 weeks) or chronically infected (> 2 weeks). All knees were evaluated following surgical treatment with radiographs and Knee Society knee score assessment. Successful eradication of infection was defined as a knee without clinical evidence of infection for a minimum of 2 years. The initial treatment modality was successful in eliminating the infection in 69 of 76 patients (90%). Infection was eventually eradicated in 72 of 76 (94%) patients. The individual clinical result was found to be more dependent on a patients medical and musculoskeletal status (patient class A, B, C) than on knee score or radiographic assessment. Careful treatment selection based on patient class and duration of infection can result in a predictable and successful result.

Impacted Particulate Allograft for Femoral Revision Total Hip Arthroplasty In vitro Mechanical Stability and Effects of Cement Pressurization

The initial migration and micromotion of the revision femoral stem stabilized with morselized impacted cancellous allograft and bone-cement and the influence of cement pressurization on fixation of the cement/allograft composite to the host were examined with human cadaver femurs. The stability of the allograft/cemented reconstruction was found to be intermediate between those of conventional cemented and cementless stems. In most cases, the stability of the reconstruction was closer to that of cemented than to that of cementless stems. This may account for histologic findings of graft incorporation in experimental and retrieved specimens reported by other authors. Although increased cement pressurization led to greater penetration of cement into the graft bed, greater cement penetration did not increase fixation strength of the cement/allograft composite to the host.

An Intraoperative Pressure-measuring Device Used in Total Knee Arthroplasties and Its Kinematics Correlations

Fluoroscopic and retrieval analyses of knee implants show considerable variability even for the same implant design, and implicate the possible importance of surgical technique and compartment pressure balance in total knee arthroplasties. This study was done to correlate intraoperative computer-assessed compartment pressure measurements with postoperative kinematics to explain these variations. Thirty-eight patients had posterior cruciate-sacrificing low-contact stress total knee arthroplasties using a balanced gap technique. At trial reduction, an instrumented tibial insert designed to record the magnitude, location, and dynamic imprint of the pressures in the medial and lateral compartments was placed into the knee. Pressures were recorded electronically for a range of motion from 0°–120°. Sixteen of the 38 patients agreed to do successive weightbearing deep knee bends under fluoroscopic surveillance. Only three of the 16 patients had condylar lift-off, but all experienced lift-off at a single flexion angle. In the three patients who had condylar lift-off, a compartment pressure imbalance, as measured by the intraoperative pressure sensor, occurred at the same flexion angle of lift-off. These data suggest that although a given implant design may have inherent kinematic tendencies, surgical technique and compartment pressure balance significantly impact kinematic performance.

Acetabular anatomy and transacetabular screw fixation at the high hip center.

A quadrant system that defines the safe acetabular locations for screw placement exists for the anatomic hip center. We wanted to develop a similar system for the high hip center. The purposes of our study were to identify the anatomic structures at risk during placement of transacetabular screws in the high hip center, to identify maximum bone depth for screw purchase, and to determine if a high hip center quadrant system could be validated to guide placement of screws during acetabular arthroplasty. For this cadaver study of nine pelves, an acetabulum was reamed superiorly into the high hip center a distance equal to ½ of the native acetabular diameter. Screws exiting the acetabular bone by 15 mm were inserted before a computed tomography scan and a precise anatomic dissection were done. Structures at risk of penetration by screws include the external iliac vessels, the obturator nerve and vessels, the superior gluteal nerve and vessels, and the sciatic nerve. We found that a quadrant system at the high hip center can demarcate safe zones for screw placement. At the high hip center, only the peripheral ½ of the posterior quadrants are safe for screw placement.

Coralline Hydroxyapatite in Complex Acetabular Reconstruction

This retrospective study examined whether a coralline hydroxyapatite bone graft substitute adequately repaired bone defects during complex acetabular reconstructions. Seventeen patients who underwent acetabular revision using Pro Osteon 500 were assessed to determine whether any cups required re-revision, whether bone had incorporated into the coralline hydroxyapatite grafts, and whether the coralline hydroxyapatite grafts resorbed with time. At latest follow-up, no cups required re-revision, but 1 had failed. Radiographic evidence of bone incorporation was observed in every coralline hydroxyapatite graft. Graft resorption was not observed.

Radiographic evaluation of screw position in revision total hip arthroplasty.

Injury to intrapelvic structures during removal of screws in revision acetabular arthroplasty is an uncommon, yet potentially serious complication. Bicortical screws are at greatest risk for causing injury during removal, especially if directed toward intrapelvic vessels and nerves. Complications can be minimized with thorough evaluation of screw position before revision surgery. A study of seven cadaveric pelves was done to determine if plain radiographic views provide useful information regarding screw position. In each pelvis, bicortical transacetabular screws were fixed in all acetabular quadrants 15 mm longer than the measured depth. Afterward, anteroposterior, inlet, Judet, and cross-table lateral radiographic views were obtained and intrapelvic dissections were done. Radiographs and intrapelvic dissections were compared to determine screw position. We found that the obturator and iliac oblique (Judet) views were most useful in defining screw position. The iliac oblique view clearly revealed screws that violated the quadrilateral surface and therefore were directed toward the obturator vessels and nerve. The obturator oblique view revealed screws that violated the anterior column and therefore were directed toward the external iliac vessels. The lateral view additionally clarified such screws by determining general anterior or posterior direction.