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Dive into the research topics where Richard D. Holly is active.

Publication


Featured researches published by Richard D. Holly.


Journal of Leukocyte Biology | 2002

Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses

Julia Parrish-Novak; Donald C. Foster; Richard D. Holly; Christopher H. Clegg

Interleukin (IL)‐21 was recently discovered using a functional cloning approach based on expression of its receptor. It is similar in domain organization and primary sequence to IL‐2 and IL‐15. Like these cytokines, IL‐21 uses the common γ chain of the IL‐2/15 receptor, which forms a heterodimeric receptor complex with IL‐21R. IL‐21 is produced by activated T cells, and it influences proliferation of T and B cells and cytolytic activity of natural killer cells. The elucidation of the unique biological effects of IL‐21 represents an intense area of interest in current cytokine biology.


Nature | 1994

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

S I Lok; Richard D. Holly; Virginia C. Broudy; Nan Lin; Mason C. Bailey; John W. Forstrom; Michele M. Buddle; Fredrick S. Hagen; Gerald Juergen Roth; Thalia Papayannopoulou; Donald C. Foster


Archive | 2006

CYTOKINE ZALPHA11 LIGAND

Julia E. Novak; Scott R. Presnell; Cindy A. Sprecher; Donald C. Foster; Richard D. Holly; Jane A. Gross; Janet V. Johnston; Andrew J. Nelson; Stacey R. Dillon; Angela K. Hammond


Archive | 2001

Methods of using zalpha11 ligand

Julia E. Novak; Scott R. Presnell; Cindy A. Sprecher; Donald C. Foster; Richard D. Holly; Jane A. Gross; Janet V. Johnston; Andrew J. Nelson; Stacey R. Dillon; Angela K. Hammond


Archive | 2001

Soluble zalpha11 cytokine receptors

Cindy A. Sprecher; Julia E. Novak; James W. West; Scott R. Presnell; Richard D. Holly; Andrew J. Nelson


Archive | 1992

Methods for producing thrombin

Richard D. Holly; Donald C. Foster


Archive | 2006

Methods of treating cancer using il-21

Andrew J. Nelson; Steven D. Hughes; Richard D. Holly


Archive | 2002

Cytokine zalpha11 ligand polynucleotides

Julia E. Novak; Scott R. Presnell; Cindy A. Sprecher; Donald C. Foster; Richard D. Holly; Jane A. Gross; Janet V. Johnston; Andrew J. Nelson; Stacey R. Dillon; Angela K. Hammond


Archive | 1994

Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide

Donald C. Foster; Mark D. Heipel; Richard D. Holly


Archive | 1990

Hybrid protein C

Donald C. Foster; Richard D. Holly

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Scott R. Presnell

Benaroya Research Institute

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