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Robert Bishop

Schering-Plough

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Featured researches published by Robert Bishop.

Bioorganic & Medicinal Chemistry Letters | 1993

Indolocarbazoles. 1. Total synthesis and protein kinase inhibiting characteristics of compounds related to K-252c.

Stuart W. McCombie; Robert Bishop; Donna Carr; Emily Dobek; Michael P. Kirkup; Paul Kirschmeier; Sue-Ing Lin; Joanne M. Petrin; Karen Rosinski; Bandarpalle B. Shankar; Oswald Wilson

Abstract The condensation of indolo[2,3-a]-carbazole ( 12 ) with 2,5-dimethoxytetrahydrofuran derivatives gave cyclofuranosylated compounds (e.g. 13 ), which were converted via dibromocompounds to the dinitriles (e.g. 25 ). Hydrolysis, hydrolysis-reduction and thiolysis afforded imides, lactams (e.g. 27 ) and their thio analogs. These compounds were potent inhibitors of the protein kinase C family.

Bioorganic & Medicinal Chemistry Letters | 2004

Bridgehead modification of trihalocycloheptabenzopyridine lead to a potent farnesyl protein transferase inhibitor with improved oral metabolic stability

F. George Njoroge; Bancha Vibulbhan; Xiongwei Shi; Corey Strickland; Paul Kirschmeier; Robert Bishop; Amin A. Nomeir; Viyyoor M. Girijavallabhan

Archive | 2001

antitumor tricyclic compounds that are inhibitors of farnesyl protein transferase.

Carmen Alvarez; John J. Baldwin; Robert Bishop; Alan B. Cooper; Jagdish A. Desai; Ronald J. Doll; Viyyoor M. Girijavallabhan; Timothy J. Guzi; Chia-Yu Huang; Ray Anthony James; Kartik M. Keertikar; Ge Li; Keith P. Minor; F. George Njoroge; Patrick A. Pinto; Dinanath F. Rane; Bama Santhanam; Bancha Vibulbhan; James Wang; Hugh Y. Zhu

Archive | 2001

Tricyclic antitumor komponenten als farnesyl protein transferase inhibitoren Tricyclic anti-tumor protein farnesyl transferase inhibitors as components

Carmen Alvarez; John J. Baldwin; Robert Bishop; Alan B. Cooper; Jagdish A. Desai; Ronald J. Doll; Viyyoor M. Girijavallabhan; Timothy Chatham Guzi; Chia-Yu Plainsboro Huang; Ray Anthony James; Kartik M. Keertikar; Ge Lujiazui Garden Li; Keith P. Minor; F. George Njoroge; Patrick Pinto; Dinanath F. Rane; Bama Santhanam; Bancha Vibulbhan; James Wang; Hugh Y. Zhu

Archive | 2001

Compuestos antitumorales triciclicos que son inhibidores de la proteina transferasa de farnesilo.

Carmen Alvarez; John J. Baldwin; Robert Bishop; Alan B. Cooper; Jagdish A. Desai; Ronald J. Doll; Viyyoor M. Girijavallabhan; Timothy J. Guzi; Chia-Yu Huang; Ray Anthony James; Kartik M. Keertikar; Ge Li; Keith P. Minor; F. George Njoroge; Patrick A. Pinto; Dinanath F. Rane; Bama Santhanam; Bancha Vibulbhan; James Wang; Hugh Y. Zhu

Archive | 1996

Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und zur behandlung von proliferativen erkrankungen Tricyclic carbamate derivatives for the inhibition of G-protein function and for treatment of proliferative diseases

Robert Bishop; J Doll; K Mallams; George F Njoroge; M Petrin; John J. Piwinski; L Wolin; G Taveras; W Remiszewski

Archive | 1996

Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und zur behandlung von proliferativen erkrankungen

Robert Bishop; J Doll; K Mallams; George F Njoroge; M Petrin; John J. Piwinski; L Wolin; G Taveras; W Remiszewski

Archive | 1996

Tricyclische amide und harnstoff-derivate anwendbar als g-protein funktion inhibitoren und für die behandlung von proliferativen erkrankungen

Robert Bishop; J Doll; K Mallams; George F Njoroge; M Petrin; John J. Piwinski; L Wolin; G Taveras; W Remiszewski

Archive | 1996

Tricyclische amide und harnstoff-derivate anwendbar als g-protein funktion inhibitoren und für die behandlung von proliferativen erkrankungen Tricyclic amide and urea derivatives applicable as G-protein function and inhibitors for the treatment of proliferative diseases

Robert Bishop; J. Ronald Doll; K. Alan Mallams; George F Njoroge; M. Joanne Cedar Grove Petrin; John J. Piwinski; W. Stacy Remiszewski; G. Arthur Taveras; L. Ronald Westfield Wolin

Archive | 1996

USE OF TRICYCLIC CARBAMATE DERIVATIVES FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES

Robert Bishop; J Doll; K Mallams; George F Njoroge; M Petrin; John J. Piwinski; L Wolin; G Taveras; W Remiszewski

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George F Njoroge

Schering-Plough

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John J. Piwinski

Schering-Plough

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J Doll

Schering-Plough

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K Mallams

Schering-Plough

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M Petrin

Schering-Plough

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G Taveras

Schering-Plough

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L Wolin

Schering-Plough

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W Remiszewski

Schering-Plough

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Ronald J. Doll

Schering-Plough

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Bancha Vibulbhan

Schering-Plough

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