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Dive into the research topics where Robert Dally is active.

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Featured researches published by Robert Dally.


Analytical Biochemistry | 1990

A fluorometric assay for HIV-protease activity using high-performance liquid chromatography

Paul P. Tamburini; Robert N. Dreyer; Jutta Hansen; Jack Letsinger; Jim Elting; Ann Gore-Willse; Robert Dally; Rudolf Dr. Hanko; David G. Osterman; Michael E. Kamarck; Heeja Yoo-Warren

A rapid sensitive method for the quantification of in vitro HIV-protease activity has been developed on the basis of the endoproteolytic conversion of N-Dns-SQ-NYPIV to N-Dns-SQNY. The use of the N-dansyl group as a fluorescence label was shown to not significantly alter the apparent kinetic parameters for the peptide-enzyme interaction. Using fluorescence detection, the dansylated product and unconverted substrate are detected in a single rapid (3 min) isocratic reverse-phase HPLC separation in quantities as low as 0.2 pmol. The method is highly reproducible and suited to a variety of applications including the analysis of large sample numbers and rigorous enzymological studies.


Archive | 1995

Aminomethylene derivaties as immunosuppressants

Richard D. Connell; David G. Osterman; Michael E. Katz; Robert Dally


Archive | 1994

Aminomethylene derivatives as immunosuppressants

Richard D. Connell; David G. Osterman; Michael E Katz; Robert Dally


Angewandte Chemie | 1991

Stereoselective Synthesis of Cyclic Dipeptide Hydroxyalkyl Isosteres via Metalated N,N‐Dialkylcarbamate 2‐Alkenyl Esters

Rudolf Dr. Hanko; Klaus Rabe; Robert Dally; Dieter Hoppe


Angewandte Chemie | 1991

Stereoselektive Synthese von cyclischen Hydroxyalkyl-Dipeptidisosteren über metallierte N,N-Dialkylcarbamidsäure-2-alkenylester†‡

Rudolf Dr. Hanko; Klaus Rabe; Robert Dally; Dieter Hoppe


Archive | 1994

Novel aminomethylene derivatives as immunosuppressants

Richard D. Connell; David G. Osterman; Michael E. Katz; Robert Dally


Archive | 2002

2,6-substituierte chromanderivate und ihre verwendung als beta-3 adrenorezeptor agonisten Agonist 2,6-substituted chroman derivatives and their use as beta-adrenoreceptor 3

J O'connor; H Ladouceur; H Bullock; Ann-Marie Campbell; Miao Dai; Robert Dally; Jacques Dumas; N Hatoum-Mokdad; Uday Khire; Wendy Lee; Qingjie Liu; B Lowe; R Magnuson; Ning Qi; E Shelekhin; Quanrong Shen; A Smith; Ming Wang


Archive | 2002

agonist 2,6-substituted chroman derivatives and their use as a beta-adrenoreceptor 3

H. William Bullock; Ann-Marie Campbell; Miao Dai; Robert Dally; Jacques Dumas; N. Holia Hatoum-Mokdad; Uday Khire; H. Gaetan Ladouceur; Wendy Lee; Qingjie Liu; B. Derek Lowe; R. Steven Magnuson; J. Stephen O'connor; Ning Qi; E. Tatiana Shelekhin; Quanrong Shen; A. Roger Madison Smith; Ming Wang


Archive | 1998

Raf kinase hemmer

Jill E. Wood; Hanno Wild; Daniel H Rogers; John Lyons; Michael E Katz; Yolanda V Caringal; Robert Dally; Wendy Lee; Roger A. Smith; Cheri Lynn Blum


Archive | 1998

Inhibiteurs de raf kinase

Jill E. Wood; Hanno Wild; Daniel H Rogers; John Lyons; Michael E Katz; Yolanda V Caringal; Robert Dally; Wendy Lee; Roger A. Smith; Cheri Lynn Blum

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