David G. Osterman
Bayer Corporation
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by David G. Osterman.
Analytical Biochemistry | 1990
Paul P. Tamburini; Robert N. Dreyer; Jutta Hansen; Jack Letsinger; Jim Elting; Ann Gore-Willse; Robert Dally; Rudolf Dr. Hanko; David G. Osterman; Michael E. Kamarck; Heeja Yoo-Warren
A rapid sensitive method for the quantification of in vitro HIV-protease activity has been developed on the basis of the endoproteolytic conversion of N-Dns-SQ-NYPIV to N-Dns-SQNY. The use of the N-dansyl group as a fluorescence label was shown to not significantly alter the apparent kinetic parameters for the peptide-enzyme interaction. Using fluorescence detection, the dansylated product and unconverted substrate are detected in a single rapid (3 min) isocratic reverse-phase HPLC separation in quantities as low as 0.2 pmol. The method is highly reproducible and suited to a variety of applications including the analysis of large sample numbers and rigorous enzymological studies.
Archive | 1993
Richard D. Connell; David G. Osterman; Michael E Katz
Archive | 1993
Richard D. Connell; David G. Osterman; Michael E Katz; Rudolf H. Hanko; Stephan Schneider
Archive | 1994
Richard D. Connell; David G. Osterman; Michael E Katz; Robert D. Dally
Archive | 1994
Richard D. Connell; David G. Osterman; Michael E Katz; Robert Dally
Archive | 1994
Richard D. Connell; David G. Osterman; Michael E Katz; Rudolf H. Hanko; Stephan Schneider
Archive | 1994
Richard D. Connell; David G. Osterman; Michael E Katz; Robert Dally
Archive | 1994
Richard D. Connell; Robert Dally; Michael E Katz; David G. Osterman; デイビツド・ジー・オスターマン; マイケル・イー・カツツ; リチヤード・デイ・コンネル; ロバート・デイ・ダリー
Archive | 1994
Richard D. Connell; David G. Osterman; Michael E Katz; Robert Dally
Archive | 1994
Richard D. Connell; David G. Osterman; Michael E Katz; Robert Dally
