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Featured researches published by Robert W. Leiby.


Synthetic Communications | 1976

Substituted 2-Aminobenzoyl Derivatives of Methylhydrazine

Robert W. Leiby; Ned D. Heindel

Abstract Acylation of arylhydrazines gives acyl 2-arylhydrazides1 while acylation of alkylhydrazines yields either 1-alkyl or 2-alkylhydrazides depending on the choice of acylating agent. Earlier examples of the variability of acylation sites in the alkylhydrazines2,3 were systematically reinvestigated by Hinman4 and Moore5 who established that esters, with methylhydrazine, gave acyl 2-methylhydrazides while anhydrides yielded acyl 1-methyl-hydrazides.


Journal of Organic Chemistry | 1988

The chemistry of L-ascorbic and D-isoascorbic acids. 1. The preparation of chiral butanetriols and -tetrols

Elie Abushanab; Purushotham Vemishetti; Robert W. Leiby; Haribansh K. Singh; Amarendra B. Mikkilineni; David C. J. Wu; Racha Saibaba; Raymond P. Panzica


Journal of Organic Chemistry | 1976

Synthesis of 3,4-dihydro- and 1,4-dihydro-5H-1,3,4-benzotriazepin-5-ones

Robert W. Leiby; Ned D. Heindel


Journal of Organic Chemistry | 1985

Synthesis of 3-amino-4(3H)-quinazolinones from N-(2-carbomethoxyphenyl)imidate esters

Robert W. Leiby


Journal of Organic Chemistry | 1977

A unique rearrangement of 3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones to 3-methylamino-4(3H)-quinazolinones

Robert W. Leiby; Ned D. Heindel


ChemInform | 1976

SYNTHESIS OF 3,4‐DIHYDRO‐ AND 1,4‐DIHYDRO‐5H‐1,3,4‐BENZOTRIAZEPIN‐5‐ONES

Robert W. Leiby; Ned D. Heindel


ChemInform | 1977

A UNIQUE REARRANGEMENT OF 3,4‐DIHYDRO‐5H‐1,3,4‐BENZOTRIAZEPIN‐5‐ONES TO 3‐METHYLAMINO‐4(3H)‐QUINAZOLINONES

Robert W. Leiby; Ned D. Heindel


Journal of Organic Chemistry | 1978

A unique ring contraction of 1,4-dihydro-5H-1,3,4-benzotriazepin-5-ones to 1-methyl-2-(methylamino)-4(1H)-quinazolinones via an intermediate Dimroth rearrangement

Robert W. Leiby; Edward G. Corley; Ned D. Heindel


ChemInform | 1978

A UNIQUE RING CONTRACTION OF 1,4-DIHYDRO-5H-1,3,4-BENZOTRIAZEPIN-5-ONES TO 1-METHYL-2-(METHYLAMINO)-4(1H)-QUINAZOLINONES VIA AN INTERMEDIATE DIMROTH REARRANGEMENT

Robert W. Leiby; Edward G. Corley; Ned D. Heindel


ChemInform | 1988

A Practical Synthesis of 1,2,4-Triazole-3-carboxylate (VI) and Its Use in the Formation of Chiral 1′,2′-seco-Nucleosides (VIII), (X) of Ribavirin.

P. Vemishetti; Robert W. Leiby; Elie Abushanab; Raymond P. Panzica

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Elie Abushanab

University of Rhode Island

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Racha Saibaba

University of Rhode Island

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