Rogério Nabor Kondo

Proliferating pilomatricoma - Case report

Proliferating pilomatricoma is proliferative, rare tumor variant of pilomatricoma. It is a benign neoplasm of hair matrix that can have potentially involve local recurrence. We report the case of a 60-year-old man who presented an asymptomatic nodule on the scalp. Histological exam demonstrated a basaloid epithelium at the periphery, filled with eosinophilic cornified material containing shadow cells. The tumor was excised and there was no evidence of recurrence one year later.

Pyoderma gangrenosum: skin grafting and hyperbaric oxygen as adjuvants in the treatment of a deep and extensive ulcer

Pyoderma gangrenosum is a rare dermatosis of unknown etiology and variable clinical presentation. The disease is challenging for the medical staff, from the frequent diagnostic difficulties to the lack of scientific evidence with a good level to support the management of extensive and refractory cases. Our patient is a 50 year-old man with an extensive and deep ulcer on the left leg, which exemplifies the therapeutic difficulties inherent to the disease and who, fortunately, has progressed with excellent result after association of hyperbaric oxygen therapy and skin grafting to the immunosuppression therapy initially proposed.

Do you know this syndrome? Noonan syndrome.

Noonan Syndrome is one of the most common genetic syndromes and also an important differential diagnosis in children presenting with syndromic facies similar to Turners syndrome phenotype. This syndrome is characterized by facial dysmorphism, congenital heart defects, short stature and also a wide phenotypic variation. This article discusses the case of a 10 year-old patient with Noonan syndrome that presented typical facies, cardiac defects (pulmonary dilatation and mitral regurgitation), dental malocclusion, micrognatism, short stature and a certain degree of learning disability.

Voce conhece esta sindrome

Noonan Syndrome is one of the most common genetic syndromes and also an important differential diagnosis in children presenting with syndromic facies similar to Turners syndrome phenotype. This syndrome is characterized by facial dysmorphism, congenital heart defects, short stature and also a wide phenotypic variation. This article discusses the case of a 10 year-old patient with Noonan syndrome that presented typical facies, cardiac defects (pulmonary dilatation and mitral regurgitation), dental malocclusion, micrognatism, short stature and a certain degree of learning disability.

Dermatite esfoliativa: estudo clínico-etiológico de 58 casos

FUNDAMENTO: Dermatite esfoliativa e sindrome cutânea caracterizada por eritema e descamacao generalizados, que pode ser consequente ou estar associada a varias doencas dermatologicas previas, doencas sistemicas ou reacoes medicamentosas. OBJETIVOS: Relatar a frequencia das diferentes causas e caracteristicas clinicas associadas a dermatite esfoliativa nos pacientes atendidos no Setor de Dermatologia do Hospital Universitario Regional do Norte do Parana, da Universidade Estadual de Londrina. METODOS: Foram revisados os registros de pacientes com diagnostico de dermatite esfoliativa diagnosticados no Hospital Universitario Regional do Norte do Parana no periodo de 10 anos. RESULTADOS: Foi encontrado o total de 58 pacientes com diagnostico de dermatite esfoliativa, com idade media de 56,89 anos. Em 33 pacientes, foi definida uma dermatose como causa (psoriase, 11 casos; dermatite de contato, nove casos; eritrodermia ictiosiforme congenita, tres casos; dermatite seborreica, cinco casos; dermatite atopica, tres casos; pitiriase rubra pilar, dois casos). Reacoes a drogas foram observadas em 11 pacientes. Em 14 casos (24%) nao foi possivel determinar a causa basica. CONCLUSOES: Numa amostra de pacientes atendidos num servico de referencia em dermatologia, a dermatite esfoliativa foi ocorrencia pouco comum, e a maior parte dos casos estava relacionada a doencas dermatologicas.

Do you know this syndrome

Noonan Syndrome is one of the most common genetic syndromes and also an important differential diagnosis in children presenting with syndromic facies similar to Turners syndrome phenotype. This syndrome is characterized by facial dysmorphism, congenital heart defects, short stature and also a wide phenotypic variation. This article discusses the case of a 10 year-old patient with Noonan syndrome that presented typical facies, cardiac defects (pulmonary dilatation and mitral regurgitation), dental malocclusion, micrognatism, short stature and a certain degree of learning disability.

Drug-induced acne and rose pearl: similarities

Drug-induced acne is a common skin condition whose classic symptoms can be similar to a rose pearl, as in the case of a male patient presenting with this condition after excessive use of a cream containing corticosteroids.

Cross-sectional study of the microbiological safety profile of reusing hyaluronic acid fillers

Facial filling with hyaluronic acid (HA) is a dermatological procedure that has been emerging today. There are not many references regarding safety of reusing the remaining product for later touch‐up in the same patient.

Ectopic hidradenoma papilliferum

Dear Editor, We report a case of a 36-year-old male patient with a two-month history of an asymptomatic, erythematous, 1 x 1cm papule of fibroelastic consistency on the left areola (Figure 1). The left axillary lymph nodes were not enlarged. We performed an excisional biopsy of the papule for diagnosis. Histopathology revealed a dermal tumor with no connection to the overlying epidermis. The lesion contained cells with papillary folds, tubules, cystically dilated spaces, and lumen lined by columnar cells with decapitation secretion, compatible with hidradenoma papilliferum (HP) (Figures 2 and 3). HP is a rare, benign, adnexal tumor that occurs almost exclusively in the anogenital region of female patients.1-4 HP appears as solitary, asymptomatic, well-circumscribed, skin-colored or reddish-brown nodules measuring from 0.5 to 1cm. HP lesions that are not located in the anogenital area are referred to as ectopic HP. 1,4,5 Many cases of HP have been reported since it was first described by Werth in 1878.5 However, very few cases of ectopic HP have been reported in male patients.4 Ectopic HP can occur on the eyelids, orbit, nose, breast, chest, abdomen, and scalp. 4, 5 The histogenesis for both anogenital and ectopic HP remains unclear. Although the presence of human papillomavirus (HPV) DNA has been identified in a few cases, it does not seem to play a role in the pathogenesis of HP. Histopathological findings show dermal tumors with no connection to the overlying epidermis, with papillary and tubular formations, cystically dilated spaces, and lumen lined by columnar cells with decapitation secretion. Such histopathology A

Primary cutaneous amelanotic melanoma and gastrointestinal stromal tumor in synchronous evolution

Gastrointestinal stromal tumor is rare digestive tract mesenchymal tumor, most often in the wall of the stomach. It is a benign neoplasm, but it can become malignant if not treated. We report a case of gastrointestinal stromal tumor that was discovered after abdominal ultrasonography during staging of a patient with primary cutaneous amelanotic melanoma. Mutation in the tyrosine kinase receptor could explain the development of two types of tumors in the same patient.