Rolla B. Hill

Infectious Pulmonary Disease in Patients Receiving Immunosuppressive Therapy for Organ Transplantation

WHOLE-organ homotransplantation is a modality of therapy that has only recently been submitted to clinical investigation in man,1 and reports on the natural history of patients so treated are therefore fragmentary. The clinical course of such patients obviously is profoundly influenced by the chemotherapy that they receive, usually including corticosteroids and immunosuppressive antimetabolites. These compounds have a wide range of effects on the host metabolic reactions, and they so alter immunologic responsiveness that changes in the spectrum of infectious disease may reasonably be expected. Up to February, 1964, 61 patients had received homotransplants or heterotransplants at this center; of these .xa0.xa0.

The clinical significance of cytomegalovirus infection in renal transplant recipients.

Excerpt The high prevalence of cytomegalovirus infection after renal transplantation has been described in reports from the Harvard group (1, 2) and from this Center (3-9). In the present communica...

Nocardiosis and Pulmonary Alveolar Proteinosis.

Excerpt Included in the original report of pulmonary alveolar proteinosis (1) were two instances in which there was associated nocardiosis. Since that time three additional reports of this associat...

Systemic Contraceptives and Liver Tumors

Excerpt Since October 1973 when Baum (1) reported seven women with benign liver tumors occurring in association with use of oral contraceptives, more than 100 cases have been reported in various ar...