Ronnie R. Crenshaw
Bristol-Myers Squibb
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Publication
Featured researches published by Ronnie R. Crenshaw.
Antimicrobial Agents and Chemotherapy | 1977
Paul Siminoff; Ronnie R. Crenshaw
Various structural analogues of the interferon inducer BL-20803 exhibited close agreement between ability to stimulate interferon production in the intact mouse and in cultures of spleen adherent leukocytes.
European Journal of Medicinal Chemistry | 1989
Ivo Monkovic; Myron Brown; George M. Luke; Robert T. Standridge; David Willner; Alfred R. Crosswell; Aldo A. Algieri; Joseph P. Buyniski; Ronnie R. Crenshaw; Peter F. Juby
Abstract A series of 2-substituted-4-amino-5-chloro-N-[2-diethylaminoethyl]benzamides was synthesized and evaluated for gastrointestinal motility enhancing activity in vitro (enhancement of field stimulated guinea pig ileum test) and in vivo (enhancement of rat stomach emptying). A number of compounds were shown to be potent gastrointestinal prokinetic agents yet were devoid of dopaminergic D2-receptor antagonism as shown by their inability to displace [3H]spiperone from brain membranes. The model compound 6b would be expected to have clinical use in a spectrum of upper gastroinstestinal motility disorders but without the central nervous system side effects characteristic of dopaminergic D2-receptor blockade in the brain.
Archive | 1976
Richard Anthony Partyka; Ronnie R. Crenshaw
Journal of Medicinal Chemistry | 1976
Ronnie R. Crenshaw; George M. Luke; Paul Siminoff
Archive | 1965
Ronnie R. Crenshaw
Archive | 1976
Richard Anthony Partyka; Ronnie R. Crenshaw
Archive | 1968
Ronnie R. Crenshaw
Archive | 1978
Ronnie R. Crenshaw; Thomas A. Montzka
Archive | 1977
Ronnie R. Crenshaw; Richard Anthony Partyka
Archive | 1977
Ronnie R. Crenshaw; George M. Luke; Richard Anthony Partyka