Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Rui M.A. Domingues is active.

Publication


Featured researches published by Rui M.A. Domingues.


Journal of Agricultural and Food Chemistry | 2009

Miscanthus x giganteus Extractives: A Source of Valuable Phenolic Compounds and Sterols

Juan José Villaverde; Rui M.A. Domingues; Carmen S.R. Freire; Armando J.D. Silvestre; C. Pascoal Neto; Pablo Ligero; A. Vega

The chemical composition of the lipophilic extracts of bark and core, of the Miscanthus x giganteus stalk, was studied by gas chromatography-mass spectrometry (GC-MS). Aromatic compounds, sterols, and fatty acids, followed by long-chain fatty alcohols, were the major families of components present in the M. x giganteus stalk. Aromatic compounds are more abundant in the M. x giganteus bark (521 mg/kg of bark), with vanillic acid, vanillin, and p-hydroxybenzaldehyde as the major compounds of this family. In the M. x giganteus core, sterols represent about 949 mg/kg of dry core with beta-sitosterol, 7-oxo-beta-sitosterol, stigmasterol, and campesterol as the major components. The detection of small amounts of esters in the GC-MS analysis with short columns explains the small increase in the abundance of the identified families after alkaline hydrolysis. The high content of valuable sterols and aromatic compounds in M. x giganteus and, particularly, in the core, which is considered a residue in most applications, can open new perspectives for the integrated upgrading of this grass within the biorefinery perspective.


International Journal of Molecular Sciences | 2012

Supercritical fluid extraction of Eucalyptus globulus bark-A promising approach for triterpenoid production.

Rui M.A. Domingues; Eduardo L.G. Oliveira; Carmen S.R. Freire; Ricardo M. Couto; Pedro Simões; Carlos Neto; Armando J.D. Silvestre; Carlos M. Silva

Eucalyptus bark contains significant amounts of triterpenoids with demonstrated bioactivity, namely triterpenic acids and their acetyl derivatives (ursolic, betulinic, oleanolic, betulonic, 3-acetylursolic, and 3-acetyloleanolic acids). In this work, the supercritical fluid extraction (SFE) of Eucalyptus globulus deciduous bark was carried out with pure and modified carbon dioxide to recover this fraction, and the results were compared with those obtained by Soxhlet extraction with dichloromethane. The effects of pressure (100–200 bar), co-solvent (ethanol) content (0, 5 and 8% wt), and multistep operation were studied in order to evaluate the applicability of SFE for their selective and efficient production. The individual extraction curves of the main families of compounds were measured, and the extracts analyzed by GC-MS. Results pointed out the influence of pressure and the important role played by the co-solvent. Ethanol can be used with advantage, since its effect is more important than increasing pressure by several tens of bar. At 160 bar and 40 °C, the introduction of 8% (wt) of ethanol greatly improves the yield of triterpenoids more than threefold.


Industrial Crops and Products | 2010

Eucalyptus globulus biomass residues from pulping industry as a source of high value triterpenic compounds

Rui M.A. Domingues; Gabriel Sousa; Carmen S.R. Freire; Armando J.D. Silvestre; C. Pascoal Neto


Industrial Crops and Products | 2011

High value triterpenic compounds from the outer barks of several Eucalyptus species cultivated in Brazil and in Portugal

Rui M.A. Domingues; Gabriel Sousa; Carlos M. Silva; Carmen S.R. Freire; Armando J.D. Silvestre; C. Pascoal Neto


Journal of Supercritical Fluids | 2013

Optimization of the supercritical fluid extraction of triterpenic acids from Eucalyptus globulus bark using experimental design

Rui M.A. Domingues; Marcelo M.R. de Melo; Eduardo L.G. Oliveira; Carlos Pascoal Neto; Armando J.D. Silvestre; Carlos M. Silva


Industrial Crops and Products | 2013

Lipophilic extractives from the bark of Eucalyptus grandis x globulus, a rich source of methyl morolate: Selective extraction with supercritical CO2

D.J.S. Patinha; Rui M.A. Domingues; Juan José Villaverde; Armandina Silva; Carlos M. Silva; Carmen S.R. Freire; C. Pascoal Neto; Armando J.D. Silvestre


Journal of Supercritical Fluids | 2012

Measurement and modeling of supercritical fluid extraction curves of Eucalyptus globulus bark: Influence of the operating conditions upon yields and extract composition

Rui M.A. Domingues; Marcelo M.R. de Melo; Carlos Pascoal Neto; Armando J.D. Silvestre; Carlos M. Silva


Mini-reviews in Organic Chemistry | 2014

Bioactive Triterpenic Acids: From Agroforestry Biomass Residues to Promising Therapeutic Tools

Rui M.A. Domingues; Angela R. Guerra; Maria F. Duarte; Carmen S.R. Freire; Carlos Pascoal Neto; Carlos Silva; Arnando J.D. Silvestre


Archive | 2011

EUCALYPTUS BIOMASS RESIDUES FROM AGRO-FOREST AND PULPING INDUSTRIES AS SOURCES OF HIGH-VALUE TRITERPENIC COMPOUNDS

Rui M.A. Domingues; David J.S. Patinha; Gabriel Sousa; Juan José Villaverde; Carlos M. Silva; Carmen S.R. Freire; Armando J.D. Silvestre; C. Pascoal Neto; S. Francisco


Journal of Supercritical Fluids | 2014

Scale-up studies of the supercritical fluid extraction of triterpenic acids from Eucalyptus globulus bark

M.M.R. de Melo; Rui M.A. Domingues; M. Sova; E. Lack; H. Seidlitz; F. Lang; Armando J.D. Silvestre; Carlos M. Silva

Collaboration


Dive into the Rui M.A. Domingues's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Angela R. Guerra

Instituto Politécnico de Beja

View shared research outputs
Researchain Logo
Decentralizing Knowledge