S. G. F. Robben
Boston Children's Hospital
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Featured researches published by S. G. F. Robben.
Calcified Tissue International | 2000
Maarten H. Lequin; R.R. van Rijn; S. G. F. Robben; Wim C. J. Hop; C. van Kuijk
Abstract Bone densitometry in children is a relatively new topic of interest within the field of osteoporosis. Bone densitometry techniques using an X-ray source have the disadvantage of radiation exposure. Also on some systems, motion artifacts are caused by long scan times. Tibial quantitative ultrasonometry (QUS) is ideally suited for children as it is radiation free and the interactive measurement provides real-time quality control. In this prospective study, we present data from 596 healthy children—309 girls, mean age 12.9 years (range 6.1–19.9), and 287 boys, mean age 12.3 years (range 6.1–19.6) from Rotterdam, The Netherlands. For all subjects, a short questionnaire regarding overall health was completed. To assess skeletal age, an X-ray of the left hand was taken and tibial QUS of the right tibia was performed using the SoundScan™ Compact. A statistically significant correlation was found between age and speed of sound (SOS)—r2boys= 0.52 and r2girls= 0.63 (both P < 0.001) and between skeletal age and SOS—r2boys= 0.56 and r2girls= 0.63 (both P < 0.001). In boys, significant increase of mean SOS is seen between Tanner stages II and III and between IV and V. In girls there is a significant increase of mean SOS among all Tanner stages, except stages II and III. This is the first study to present normative tibial QUS data for Caucasian children and adolescents. In this study, normative data relative to skeletal age are also provided, facilitating the implementation of this technique in children with growth disorders showing dissociation between calendar and skeletal age.
British Journal of Radiology | 1994
M Meradji; S M Hussain; S. G. F. Robben; Wim C. J. Hop
In early childhood intussusception a characteristic gas pattern is often visible on plain radiographs which can be used for diagnosis. To test this hypothesis, radiographs of 163 children with intussusception, and as many controls, were reviewed. By using multivariable analysis, it appeared that five out of seven parameters (reduced amount of gas in the jejunum; lateralization of the ileum; indiscernible caecum; reduced amount of feces in the colon; and visibility of the intussusceptum) had discriminatory value. For each parameter a weighting (in points) was derived and the patients were classified: the higher the score the more likely that an intussusception was present. A sensitivity of 90% and a specificity of 90% were obtained.
Pediatric Radiology | 1999
Jonathan I. M. L. Verbeke; Anja A. P. H. Verberne; Jan C. den Hollander; S. G. F. Robben
Abstract A 6-year-old girl with an inflammatory myofibroblastic tumour of the lung is presented. The radiological features of this lesion are often atypical, as in this case, presenting as progressive atelectasis. The differential diagnosis is extensive and can be difficult, despite modern imaging techniques.
Pediatric Radiology | 1999
S. G. F. Robben; Marsha Boesten; Joska Linmans; Maarten H. Lequin; Rien M. Nijman
Objective. To evaluate the significance of thickening of the wall of the renal collecting system by US. Materials and methods. Wall thickening of the renal collecting system was seen during US in 62 collecting systems of 51 patients over a period of 2 years. The medical and radiological records of these patients were reviewed with special attention to the definitive diagnosis and other clinical and radiological parameters. Moreover, a control group consisting of 48 renal collecting systems was examined to establish normal values for the thickness of the wall of the collecting system. Results. Of the 62 collecting systems (mean wall thickness 1.6 mm, range 0.8–3.1 mm), vesicoureteric reflux (VUR) was present in 18 cases, urinary tract infection (UTI) in 11, and both VUR and UTI in 9 cases. In 10 cases, intermittent dilatation was present caused by primary obstructive megaureter (n = 2), pelvi-ureteric junction stenosis (n = 4), high-pressure bladder (n = 3), or of unknown cause (n = 1). In 11 cases, transient dilatation had been present in the recent past (usually prenatally detected hydronephrosis), but had disappeared at the time of the US examination. In 3 patients, no definite cause for the wall thickening could be established. In the control group, wall thickness ranged from 0.1 to 0.8 mm. Conclusions. The upper limit for wall thickness of the normal collecting system in children is 0.8 mm. Thickening of the wall of more than 0.8 mm should be considered as pathological and is caused by urinary tract infection, intermittent dilatation (e. g., VUR), and dilatation in the recent past.
Calcified Tissue International | 1999
Maarten H. Lequin; R. R. van Rijn; S. G. F. Robben; Wim C. J. Hop; S. Dijkhuis; M. M. E. G. Fijten; L. A. W. Meijer; C. van Kuijk
Abstract. Tibial quantitative ultrasonometry is a relatively novel technique in the field of bone sonometry, an emerging alternative to bone densitometry. The implementation of this technique in a pediatric population could prove valuable from a clinical as well as a research viewpoint. In clinical practice it is necessary to know the precision of this technique and the possible influence on measurements before implementation. This study presents the precision in a Caucasian pediatric population and the influence of measurement site, dexterity, brand of coupling gel, and temperature of coupling gel. To assess intra- and interobserver variance duplicate measurements, with repositioning, ultrasonometry was performed in 10 children over a short period of time. The observers were blinded for the results of the other observer and after each measurement the skin markings were removed. Intraobserver variance for operator one (MHL) and for observer two (SFGR) was CV 0.43%. The interobserver variance was CV 0.61%. Left midtibial and right midtibial speed of sound (SOS) measurements showed no significant differences. There were, however, significant differences in both boys and girls between right proximal versus right midtibial, right midtibial versus right distal, and right proximal versus right distal (for all P < 0.001). One-way analysis of variance (ANOVA) showed that neither the use of different coupling gels nor an increase in gel temperature had a significant influence on measurements. The results of our study show that tibial quantitative ultrasonography (QUS) is a highly reproducible technique in a Caucasian pediatric population.
European Journal of Pediatrics | 1995
E. de Vries; S. G. F. Robben; J. N. van den Anker
The radiological approach of a child with severe cervical spinal cord injury after a difficult breech delivery is presented. This diagnosis is often missed due to concurrent asphyxia. Ultrasound studies clearly showed the localisation and the extent of the injury. These findings were later confirmed by MRI.ConclusionUltrasonography is recommended as the initial imaging technique to evaluate possible spinal cord lesions in the neonate.
Pediatric Radiology | 1994
Jaap Bakker; S. G. F. Robben; Frans W.J. Hazebroek; Morteza Meradji
We report on a newborn with a large arterioportal fistula of the liver complicated by a sudden reversal of flow in the portal and superior mesenteric vein, leading to congestion and ischemia of the small intestine. Ultrasound, duplex Doppler sonography and angiographic features are presented. Ligation of the hepatic artery led to a complete recovery.
Pediatric Radiology | 1992
J. N. van den Anker; W. Baerts; J. M. E. Quak; S. G. F. Robben; Morteza Meradji
A case of iatrogenic perforation of the lamina cribrosa, followed by intracranial placement of a nasogastric tube in a preterm neonate is described. By routine ultrasound examination of the brain an echogenic structure was seen, which was radiographically diagnosed as a nasogastric tube. The tube was manually removed under antibiotic prophylaxis. No complications were observed. The false route disappeared and long-term follow-up showed no neurological side effects.
Journal of Clinical Densitometry | 2001
Maarten H. Lequin; W. C. J. Hop; Rick R. van Rijn; Marieke C.H.W. Bukkems; Leonieke L.J. Verhaak; S. G. F. Robben; Cees Van Kuijk
In the field of bone densitometry, attention has recently been focused on the pediatric population. Quantitative ultrasound (QUS) as bone assessment technique has many advantages for children in comparison with bone assessment techniques that use ionizing radiation. In this pilot study, we investigated the use of calcaneal and tibial QUS systems in a healthy Caucasian pediatric population. We studied 120 healthy Caucasian Dutch children between ages 7 and 19 yr: 53 boys (mean age of 12.5 yr, range 4.5-18) and 67 girls (mean age of 13.5 yr; range 7.1-19). We recruited children from a large population who previously had participated in a bone assessment study performed at our hospital. Two operators performed calcaneal QUS of the right calcaneus and tibial QUS of the right tibia. The correlation between calcaneal and tibial ultrasound was modest but significant (r = 0.29; p < 0.01). Using the calcaneal device, we found in girls a weak positive correlation between skeletal age and speed of sound (SOS) (r = 0.38), broadband ultrasound attenuation (r = 0.57), and quantitative ultrasound index (r = 0.46), all with a value of p < 0.01. For boys all parameters failed to reach significance. Using the tibial device, we found a good correlation between skeletal age and SOS in girls (r = 0.76) and modest correlation in boys (r = 0.50), both with a value of p < 0.01. This is one of the first studies to present a comparison between two ultrasound techniques in children. At present we feel that, in light of the poor correlation with skeletal age, calcaneal ultrasound has yet to prove its efficacy in children. Tibial ultrasound seems to be a good bone assessment technique in children.
Journal of Pediatric Surgery | 1995
Frans W.J. Hazebroek; Dick Tibboel; S. G. F. Robben; Jan Hein L.J. Bergmeyer; Jan C. Molenaar
The authors report their experience with hepatic artery ligation in two newborns, as well as relevant findings from a literature review. A 2-day-old boy had progressive cardiac and respiratory difficulty. A firm liver was palpable, with an overlying thrill. Sonography and arteriography showed diffuse arteriovenous shunting in both liver lobes. Hepatic artery ligation provided remarkable hemodynamic and clinical improvement. Another boy was admitted 3 weeks after birth because of bilious vomiting with abdominal distension and bloody stools. Abdominal examination showed a large liver with a systolic bruit and thrill. X-rays showed cardiac enlargement and dilated bowel loops with air-fluid levels. Arteriography and sonography showed arteriovenous and arterioportal venous shunting. Laparotomy was performed, and a large vascular malformation was palpated in both liver lobes. The entire bowel was congested and cyanotic, but there were no signs of obstruction. This patient had acute portal hypertension imitating intestinal obstruction. Ligation of the hepatic artery improved the color of the bowel, and the thrill disappeared. Five and nearly 4 years after the operation, both boys are growing normally without medication or diet. Sonography showed almost complete resolution of the hemangiomas.