S. Kosak
Medical University of Vienna
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Publication
Featured researches published by S. Kosak.
PLOS ONE | 2015
Michael Hiesmayr; Sophie Frantal; Karin Schindler; Michael Themessl-Huber; M. Mouhieddine; Christian Schuh; Elisabeth Pernicka; Stéphane M. Schneider; Pierre Singer; Olle Ljunqvist; Claude Pichard; Alessandro Laviano; S. Kosak; Peter Bauer
Objective To develop a simple scoring system to predict 30 day in-hospital mortality of in-patients excluding those from intensive care units based on easily obtainable demographic, disease and nutrition related patient data. Methods Score development with general estimation equation methodology and model selection by P-value thresholding based on a cross-sectional sample of 52 risk indicators with 123 item classes collected with questionnaires and stored in an multilingual online database. Setting Worldwide prospective cross-sectional cohort with 30 day in-hospital mortality from the nutritionDay 2006-2009 and an external validation sample from 2012. Results We included 43894 patients from 2480 units in 32 countries. 1631(3.72%) patients died within 30 days in hospital. The Patient- And Nutrition-Derived Outcome Risk Assessment (PANDORA) score predicts 30-day hospital mortality based on 7 indicators with 31 item classes on a scale from 0 to 75 points. The indicators are age (0 to 17 points), nutrient intake on nutritionDay (0 to 12 points), mobility (0 to 11 points), fluid status (0 to 10 points), BMI (0 to 9 points), cancer (9 points) and main patient group (0 to 7 points). An appropriate model fit has been achieved. The area under the receiver operating characteristic curve for mortality prediction was 0.82 in the development sample and 0.79 in the external validation sample. Conclusions The PANDORA score is a simple, robust scoring system for a general population of hospitalised patients to be used for risk stratification and benchmarking.
Clinical Nutrition | 2014
Miriam Theilla; M. Grinev; S. Kosak; Michael Hiesmayr; Pierre Singer
Results: The result indicated that 67% of families were Turkish, 32% Kurdish and only 1% was from other ethnicities. Highest level of education in head of the families was elementary school or junior high school and their careers were independent workers. Results of studying milk consumption in our Iranian study groups implied that each person consumes approximately half of the glass of milk (118ml). The most widely consumed milk in urban and rural families was bulk milk (62.5%) which the average consumption of 478.6±22.6ml in cities and 730.4±64.4ml in rural areas weekly. Moreover, milk consumption in three cites of west Azarbaijan (Orumie, Mahabad and khoy) was reported 665.6±38.8, 375.3±35.8, and 328.4±30.7ml per week, respectively. Conclusion: Designing and running policies in practical ways to increase milk consumption seems necessary and must paid attentions. Solving milk contribution issues, changing traditional ways of milk consumption and informing the society by media should be in high priorities in order to promote health level in different groups of society.
Clinical Nutrition | 2014
Pierre Singer; S. Kosak; Alessandro Laviano; M. Mouhieddine; Michael Hiesmayr
Rationale: ASPEN and ESPEN state that glutamine may be a benefit on bone marrow transplantation (BMT). A Cochrane Review asserted that no clinical significant benefit was achieved [1]. The purpose of this study is to determine the effectiveness of glutamine supplementation of PN in BMT patients. Methods: A retrospective cohort study was conducted in CHLN. Data were collected from 1/01/2012 to 31/12/2013 from medical prescriptions. The patients included were all BMT patients. The exposed group underwent PN supplemented with glutamine and the non-exposed group did not. Three variables were analysed: albumin; c reactive protein and neutrophil absolute count from day 1 glutamine (baseline value) to D5, D10 and D17. In the non-exposed group day 1 was considered the first day of PN. Results were analyzed by independent student t test. Results: Data were collected from 24 patients, 8 exposed to glutamine and 16 non-exposed. There was a decrease in albumin’s analysis in both groups. There was not a difference statistically significant between the two groups (p value >0.1). The CPR analysis did not revealed any difference between the two groups (p value >0.1). The average neutrophil absolute count in the exposed group was higher, though not statistically significant (p value >0.1). There was a suggestion of an improvement of the immune system on the exposed group. Conclusion: No clear evidence of an association between glutamine supplementation and nutritional and immunological status was found. It was suggested that there is a possible improvement on nutritional and immunological status with glutamine supplementation. Nevertheless, more data is needed to assess this question.
Clinical Nutrition | 2014
D. Volkert; R. Diekmann; R. Luzsa; C. Kolb; M. Mouhieddine; S. Kosak; Karin Schindler; Michael Hiesmayr; C.C. Sieber
LB015-MON EFFECTS OF PARENTERAL NUTRITION CONTAINING THREE TYPES OF GLUTAMINE DIPEPTIDE ON GUT MUCOSAL MORPHOLOGY AND IMMUNOGLOBULIN A LEVEL S. Murakoshi1, K. Fukatsu1, T. Moriya2, T. Miyakuni3, M. Ri4, H. Yasuhara1. 1Surgical Center, The University of Tokyo Hospital, Tokyo, 2Surgery, National Defense Medical College, Tokorozawa, 3Digestive Surgery, Nihon University School of Medicine, 4Gastrointestinal Surgery, The University of Tokyo, Tokyo, Japan
The American Journal of Clinical Nutrition | 2016
Karin Schindler; Michael Themessl-Huber; Michael Hiesmayr; S. Kosak; Mitja Lainscak; Alessandro Laviano; Olle Ljungqvist; M. Mouhieddine; Stéphane M. Schneider; Marian A.E. de van der Schueren; Tatjana Schütz; Christian Schuh; Pierre Singer; Peter Bauer; Claude Pichard
Clinical Nutrition | 2016
Daniela Abigail Navarro; Mona Boaz; Ilan Krause; Avishay Elis; Karina Chernov; Mursi Giabra; Miriam Levy; Agnes Giboreau; S. Kosak; M. Mouhieddine; Pierre Singer
European Respiratory Journal | 2016
Mitja Lainscak; Annemie M. W. J. Schols; Jerneja Farkas; I. Sulz; Michael Themessl-Huber; Alessandro Laviano; S. Kosak; Michael Hiesmayr; Karin Schindler
Clinical Nutrition | 2017
R. Woerdenbach; I. Sulz; S. Kosak; Stephan C. Bischoff; Karin Schindler; Michael Hiesmayr; R. Barazzoni
PLOS ONE | 2015
Michael Hiesmayr; Sophie Frantal; Karin Schindler; Michael Themessl-Huber; M. Mouhieddine; Christian Schuh; Elisabeth Pernicka; Stéphane M. Schneider; Pierre Singer; Olle Ljunqvist; Claude Pichard; Alessandro Laviano; S. Kosak; Peter Bauer
Clinical Nutrition | 2015
S. Kosak; M. Mouhieddine; Pierre Singer; Michael Themessl-Huber; Alessandro Laviano; Michael Hiesmayr; Karin Schindler