S. S. Herbst

P12.10: Relationship between fetal chest size and biometric parameters by three‐dimensional ultrasound using the multiplanar method

women were referred for fetal cardiac screening, the remainder for suspected abnormalities. Fetal Cardiac abnormalities were diagnosed in 16/375 (4.3%) of ‘high risk’ screened women. They included 3/61 (5%) screened women with maternal cardiac disease, 9/166 (5.4%) previous child/sibling? with CHD, 4/34 (11.8%) of screened women with diabetes mellitus. Fetal cardiac abnormalities were identified in 18/375 (4.8%) women who had multiple risk factors. There were no obvious fetal cardiac defects among screened groups with a history of paternal CHD, previous child with CHD, maternal antibodies, and history of drug intake. Conclusions: The rate of antenatally diagnosed cardiac defects is higher than expected among our screened population. However, subgroup analysis revealed that it may vary between groups. Future studies are required to evaluate the implication of implementation of routine fetal cardiac screening policy on the antenatal detection rate of CHD and its management.

P08.18: Relationship between lung area to chest size ratio in normal fetuses by three‐dimensional ultrasound using the multiplanar method

of 21 chest size. The Bland-Altman analysis was used to compare the measurement agreement and bias for a single observer. Results: One hundred and twenty seven examinations were perfomed. The chest size ranged from 15.0 to 17.3 cm with mean of 16.6 cm (±0.7 cm, SD) on the 24th week to 21.5 to 24.8 cm with mean of 23.1 cm (±0.8 cm) on the 32nd week. The intra-observer variability study utilizing the intraclass correlation coefficient was of 0.919. Conclusions: The fetal chest measurement by multiplanar method of 3-dimensional shows good reproducibility and can be utilized to quantify the thoracic circumference.

P08.17: Reference range of fetal chest size by three-dimensional ultrasound using the multiplanar method

Objectives: To determine the prevalence of the aberrant (right or left) subclavian artery in chromosomally normal and abnormal fetuses. Methods: The study was performed at two referral centers for CHD. Fetal echocardiography was performed prospectively in the first and second trimester to identify the subclavian artery and to determine whether this was normal or aberrant. Results: Over a period of a two years we were able to identify an aberrant subclavian artery in 0.9% of chromosomally normal fetuses and in 10% of chromosomally abnormal fetuses. Conclusions: The presence of the aberrant subclavian artery is more common in chromosomally abnormal than normal fetuses.

OP25.06: Effects of the cerclage on cervical length estimated by transvaginal ultrasound and the impact of these variations on prematurity

S. E. Taher1, M. Chandiramani2, P. Soutter1, S. Arulkumaran, J. Eliahoo4, T. Teoh3, S. Hassan3, A. McIndoe1, A. Shennan2, P. R. Bennett1 1Obstetrics and Gynaecology, Imperial College, London, United Kingdom; 2Obstetrics and Gynaecology, ST Thomas’ Hospital, London, United Kingdom; 3Fetal Medicine, St Mary’s Hospital, London, United Kingdom; 4Staistical advisory department, Imperial College, London, United Kingdom

OC16.09: Reproducibility of fetal renal volume by three-dimensional ultrasonography using the rotational method

Objective: To evaluate the correlation between fetal renal volume (FRV), determined by three-dimensional ultrasonography (3DUS), and two-dimensional biometric parameters. Methods: A longitudinal prospective study was conducted on 57 women between 24 and 34 weeks of a healthy pregnancy. The volumes of both fetal kidneys were measured with 3DUS using the VOCAL (Virtual Organ Computer-aided AnaLysis) method with a 300 rotation angle. Correlation between FRV and biometric parameters biparietal diameter (BPD), cranial circumference (CC), femoral length (FL), abdominal circumference (AC) and estimated fetal weight (EFW) was evaluated using polynomial regressions, with adjustments made by the coefficient of determination (R2). Results: FRV was highly correlated with all fetal biometric parameters and all equations were of the linear type: FRV= 0,27 × BPD − 11,57 (R2= 0,70); FRV= 0,07 × CC − 12,36 (R2= 0,74); FRV= 0,31 × FL − 8,99 (R2= 0,69); FRV= 0,063 × AC − 73,22 (R2= 0,67); FRV= 0,004 × EFW + 2,76 (R2= 0,61). Conclusions: FRV assessed by 3DUS using the VOCAL method was highly correlated with two-dimensional biometric parameters.

OC16.08: Correlation of fetal renal volume by 3D-sonography and bidimensional biometric parameters

Objective: To evaluate the correlation between fetal renal volume (FRV), determined by three-dimensional ultrasonography (3DUS), and two-dimensional biometric parameters. Methods: A longitudinal prospective study was conducted on 57 women between 24 and 34 weeks of a healthy pregnancy. The volumes of both fetal kidneys were measured with 3DUS using the VOCAL (Virtual Organ Computer-aided AnaLysis) method with a 300 rotation angle. Correlation between FRV and biometric parameters biparietal diameter (BPD), cranial circumference (CC), femoral length (FL), abdominal circumference (AC) and estimated fetal weight (EFW) was evaluated using polynomial regressions, with adjustments made by the coefficient of determination (R2). Results: FRV was highly correlated with all fetal biometric parameters and all equations were of the linear type: FRV= 0,27 × BPD − 11,57 (R2= 0,70); FRV= 0,07 × CC − 12,36 (R2= 0,74); FRV= 0,31 × FL − 8,99 (R2= 0,69); FRV= 0,063 × AC − 73,22 (R2= 0,67); FRV= 0,004 × EFW + 2,76 (R2= 0,61). Conclusions: FRV assessed by 3DUS using the VOCAL method was highly correlated with two-dimensional biometric parameters.

P27.02: Three-dimensional ultrasonography of the cerebellum, cisterna magna, fourth ventricle and vermis cerebellar using slices ultrasound imaging (3DXi)

Background: Sternal clefts are rare congenital anomalies that may occur in isolation or in association with other structural malformations. The sternal malformation/vascular dysplasia association consists of sternal clefts with hemangiomas of the skin and internal organs. Abnormalities of the sternum have also been described in the PHACES syndrome which consists of posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, and eye abnormalities. Case: We report a case and associated images of an infant prenatally diagnosed with an aortic aneurysm and chest wall deformity. Postnatally, echocardiogram and MRI revealed a large aneurysm of the proximal descending aorta measuring 1.1 × 1.8 cm. The aneurysm began just distal to the origin of the left carotid artery, and a moderate pre-aneurysmal coarctation was noted. The origin of the left subclavian artery was distal to the aneurysm. In addition, partial sternal cleft with agenesis of the manubrium was noted. The intracranial anatomy was normal, and U/S and MRI revealed no hemangiomas of the head and neck vessels. Dermatologic evaluation revealed no evidence of cutaneous hemangiomas. Bronchoscopy revealed no hemangiomas of the respiratory tract. Ophthalmologic exam revealed normal ocular anatomy. Conclusion: Hemangiomas are the hallmark of both the sternal malformation/vascular dysplasia association and PHACES syndrome. We have, however, identified a case of sternal cleft with aortic aneurysm in the absence of cutaneous or visceral hemangiomas. Although these malformations may be unrelated, this case may also represent a variant of the PHACES syndrome.