Sachiko Koike
Kyoto University
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Radiation Research | 1990
Koji Ono; Yasushi Nagata; Keizo Akuta; Mitsuyuki Abe; Koichi Ando; Sachiko Koike
The usefulness of the micronucleus assay for investigating the radiation response of hepatocytes was examined. The frequency was defined as the ratio of the total number of micronuclei to the number of hepatocytes examined. The dose-response curves were curvilinear after X rays and linear after neutrons. These dose-response curves were analyzed by a linear-quadratic model, frequency = aD + bD2 + c. The a/b ratio was 3.03 +/- 1.26 Gy following X irradiation. This value is within the range of the alpha/beta ratios reported by others using the clonogenic assay of hepatocytes. While the a/b value for neutrons was 24.3 +/- 11.7 Gy, the maximum relative biological effectiveness of neutrons was 6.30 +/- 2.53. Since the micronucleus assay is simple and rapid, it may be a good tool for evaluating the radiation response of hepatocytes in vivo.
Archive | 2014
Akiko Uzawa; Ryoichi Hirayama; Yoshitaka Matsumoto; Kana Koda; Sachiko Koike; Koichi Ando; Yoshiya Furusawa
The Japan Radiation Research Society Annual Meeting Abstracts The 52nd Annual Meeting of the Japan Radiation Research Society | 2009
Sachiko Koike; Koichi Ando; Akiko Uzawa; Yoshiya Furusawa; Ryoichi Hirayama; Yoshitaka Matsumoto; Mitsuaki Yoshida; Ryuichi Okayasu
The Japan Radiation Research Society Annual Meeting Abstracts The 52nd Annual Meeting of the Japan Radiation Research Society | 2009
Yoshitaka Matsumoto; Sachiko Koike; Akiko Uzawa; Ryoichi Hirayama; Sei Sai; Nobuhiro Takase; Koichi Ando; Ryuichi Okayasu; Yoshiya Furusawa
The Japan Radiation Research Society Annual Meeting Abstracts The 47th Annual Meeting of The Japan Radiation Research Society | 2004
Koichi Ando; Akiko Uzawa; Nobuhiko Takai; Sachiko Koike; Takeshi Fukawa; Yoshiya Furusawa; Ryoichi Hirayama; Mizuho Aoki; Yoshitaka Matsumoto; Yasuyuki Miyato
The Japan Radiation Research Society Annual Meeting Abstracts The 46th Annual Meeting of The Japan Radiation Research Society | 2003
Sachiko Koike; Koichi Ando; Akiko Uzawa; Yoshiya Furusawa; Nobuhiko Takai; Takeshi Fukawa; Mizuho Aoki; Manami Monobe; Yasuyuki Miyato; Sinichiro Satoh
The Japan Radiation Research Society Annual Meeting Abstracts The 46th Annual Meeting of The Japan Radiation Research Society | 2003
Koichi Ando; Akiko Uzawa; Takeshi Fukawa; Nobuhiko Takai; Mizuho Aoki; Sachiko Koike; Yoshiya Furusawa; Yasuyuki Miyato; Manami Monobe; Guangming Zhou
Archive | 2003
Akiko Uzawa; Koichi Ando; Takeshi Fukawa; Mizuho Aoki; Nobuhiko Takai; Yasuyuki Miyato; Guangming Zhou; Sachiko Koike
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2001
Takeshi Fukawa; Kyoji Honma; Takehiko Satoh; Kotaro Oka; Sachiko Koike; Koichi Ando; Kazuo Tanishita
Radiation Research: A Twentieth-century Perspective#R##N#Congress Abstracts | 1991
Mayumi Iwakawa; Koichi Ando; Sachiko Koike