Sadhan Mondal
Visva-Bharati University
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Featured researches published by Sadhan Mondal.
Archiv Der Pharmazie | 2011
Goutam Brahmachari; Lalan C. Mandal; Rajiv Roy; Sadhan Mondal; Arun K. Brahmachari
Stevioside, an ent‐kaurene type of diterpenoid glycoside, is a natural sweetener extracted from leaves of Stevia rebaudiana (Bertoni) Bertoni. Stevioside and a few related compounds are regarded as the most common active principles of the plant. Such phytochemicals have not only been established as non‐caloric sweeteners, but reported to exhibit some other pharmacological activities also. In this article, natural distribution of stevioside and related compounds, their structural features, plausible biosynthetic pathways along with an insight into the structure–sweetness relationship are presented. Besides, the pharmacokinetics, wide‐range of pharmacological potentials, safety evaluation and clinical trials of these ent‐kaurene glycosides are revisited.
Fitoterapia | 2013
Goutam Brahmachari; Narayan C. Mandal; Rajiv Roy; Ranjan Ghosh; Soma Barman; Sajal Sarkar; Shyamal K. Jash; Sadhan Mondal
A new pentacyclic triterpenoid constituent, characterized as 3-oxo-olean-12(13),18(19)-dien-29α-carboxylic acid (1) on the basis of detailed spectral studies, was isolated from the aerial parts and roots of Limnophila indica (Scrophulariaceae). Compound 1 exhibited considerable antibacterial activity against three Gram-positive bacteria viz. Bacillus subtilis, Staphylococcus aureus and Listeria monocytogenes (MICs within a range of 25-30 μg/ml) and moderate activity against four Gram-negative bacteria Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, and Pantoea ananatis (MICs within a range of 30-100 μg/ml). The plant pathogenic bacterium P. ananatis and human pathogenic S. typhimurium responded at comparatively higher concentrations of the compound 1, which were 75 and 100 μg/ml respectively. The compound inhibited the growth of Gram-positive B. subtilis and Gram-negative P. aeruginosa completely with a clear bactericidal mode of action at their MIC values. The compound upon treatment on both B. subtilis and P. aeruginosa released substantial amount of nucleic acid in the external medium and also effected the change of morphology towards pleomorphicity, thereby indicating its probable action on cell membrane. Furthermore, the triterpenoid 1 was found not to inhibit a probiotic lactic acid bacterium Lactococcus lactis subsp. lactis LABW4 under in vitro condition and to possess no toxicity in Swiss albino mice.
Journal of Chemical Research-s | 2003
Goutam Brahmachari; Dilip Gorai; Sadhan Mondal; Arindam Gangopadhyay; Dipak Chatterjee
A new xanthone 1,3,6-trihydroxy-8-methoxyxanthone, was isolated from chloroform extract of the whole plant of Hoppea fastigiata and the structure was elucidated on the basis of spectroscopic and chemical studies. The xanthone molecule has an unusual oxygenation pattern (1,3,6, 8) and is of chemotaxonomic interest.
Chemistry & Biodiversity | 2004
Goutam Brahmachari; Sadhan Mondal; Arindam Gangopadhyay; Dilip Gorai; Bodhiswatta Mukhopadhyay; Shamal Saha; Arun K. Brahmachari
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry | 2004
Goutam Brahmachari; Dilip Gorai; D. Chatterjee; Sadhan Mondal; B. Mistri
Bulletin of Materials Science | 2007
Deepak Sharma; Vivek K. Gupta; Goutam Brahmachari; Sadhan Mondal; Arindam Gangopadhyay
Journal of The Chinese Chemical Society | 2004
K. S. Mukherjee; B. Mukhopadhyay; Sadhan Mondal; Dilip Gorai; Goutam Brahmachari
Journal of Scientific & Industrial Research | 2003
Goutam Brahmachari; Sadhan Mondal; D. Chatterjee; Arun K. Brahmachari
Archive | 2014
Shyamal K. Jash; Sadhan Mondal
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry | 2003
K. S. Mukherjee; Sadhan Mondal; S. M. A. Sohel; P. Mukherjee; D. Chatterjee; Goutam Brahmachari