Sarah L. Heald | Researchain

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Featured researches published by Sarah L. Heald.

Experimental Mycology | 1981

The identification of ergosterol and Δ9(11)-dehydroergosterol from mycelia ofCoccidioides immitis by reverse-phase high-performance liquid and gas chromatography and ultraviolet and mass spectrometry

Sarah L. Heald; Peter W. Jeffs; Robert W. Wheat

A previous reported unidentified sterol, C28H42O, isolated from arthrospores and mycelia ofCoccidioides immitis, is identified here as Δ9(11)-dehydroergosterol (ergosta-5,7,9(11),22-tetraen-3β-ol) by reverse-phase high-performance liquid and gas-liquid chromatography and ultraviolet and mass spectrometry. In addition, ergosterol (ergosta-5,7,22-trien-3β-ol) and Δ9(11)-dehydroergosterol were found as fatty acid esters in approximate ratios of 3:1, respectively, in fresh acetone extracts of 4-day mycelial growth of several strains ofC. immitis.

Journal of Biological Chemistry | 1982

125I-labeled p-azidobenzylcarazolol, a photoaffinity label for the beta-adrenergic receptor. Characterization of the ligand and photoaffinity labeling of beta 1- and beta 2-adrenergic receptors.

T N Lavin; Ponnal Nambi; Sarah L. Heald; Peter W. Jeffs; Robert J. Lefkowitz; Marc G. Caron

Journal of Biological Chemistry | 1984

Photoaffinity labeling of mammalian alpha 1-adrenergic receptors. Identification of the ligand binding subunit with a high affinity radioiodinated probe.

L. M. F. Leeb-Lundberg; K. E. J. Dickinson; Sarah L. Heald; J. E. S. Wikberg; P O Hagen; J F DeBernardis; M Winn; D L Arendsen; Robert J. Lefkowitz; Marc G. Caron

Proceedings of the National Academy of Sciences of the United States of America | 1982

The beta-adrenergic receptor: rapid purification and covalent labeling by photoaffinity crosslinking

R G Shorr; Sarah L. Heald; Peter W. Jeffs; T N Lavin; M W Strohsacker; Robert J. Lefkowitz; Marc G. Caron

Journal of Biological Chemistry | 1982

Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling.

Jeffrey M. Stadel; Ponnal Nambi; T N Lavin; Sarah L. Heald; Marc G. Caron; Robert J. Lefkowitz

Journal of Biological Chemistry | 1981

Photoaffinity labeling of the beta-adrenergic receptor.

T N Lavin; Sarah L. Heald; Peter W. Jeffs; R G Shorr; Robert J. Lefkowitz; Marc G. Caron

The Journal of Antibiotics | 1987

Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: discovery, taxonomy, activity and structure elucidation.

Siegfried Benjamin Christensen Iv; H. S. Allaudeen; Michael R. Burke; Steven A. Carr; Shang-en Chung; Peter Arletti Dephillips; John Joseph Dingerdissen; Michael Dipaolo; Albert J. Giovenella; Sarah L. Heald; Lewis B. Killmer; Bruce A. Mico; Luciano Mueller; Charles H. Pan; Benjamin L. Poehland; James B. Rake; Gerald D. Roberts; Marcia C. Shearer; Robert D. Sitrin; Louis J. Nisbet; Peter W. Jeffs

Journal of the American Chemical Society | 1986