Sau W. Cheung
Washington University in St. Louis
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Sau W. Cheung.
Cytogenetic and Genome Research | 1990
Sau W. Cheung; L. Sun; Terry Featherstone
Four individuals carrying different Robertsonian translocations (13q;14q, 14q;21q, 14q;15q, and 13q;21q) were studied to determine the breakpoints involved in the generation of these derivative chromosomes. Sequential high-resolution G-banding, in situ hybridization using alphoid and ribosomal DNA probes, and C-banding were performed. In addition, silver staining was also used for visualization of the NOR region. The results provide direct molecular cytogenetic evidence that Robertsonian translocations can take place in different regions in both the short arm and proximal long arm of acrocentric chromosomes. Three different types of breakpoints were identified: between the ribosomal or alphoid sequences, as deduced from the banding and in situ hybridization results, and breaks in two seemingly unrelated regions on the two different chromosomes. The use of conventional cytogenetic techniques together with molecular studies allowed more precise evaluation of the breakpoints involved in Robertsonian translocations than either approach alone might have done.
Human Genetics | 1985
Sau W. Cheung; James P. Crane; Ann C. Burgess
SummaryWhile standard Giemsa banding is generally adequate for amniotic fluid chromosome analysis, small deletions, duplications, or translocation breakpoints involving Gnegative bands may be difficult to appreciate. We report a method for producing high resolution R banding in human amniotic fluid cultures using the BrdU-Hoechst 33258-Giemsa (RBG) technique. RBG banding can be useful in confirming and precisely defining structural abnormalities in amniotic fluid cultures.
Prenatal Diagnosis | 1988
James P. Crane; Sau W. Cheung
Prenatal Diagnosis | 1987
Sau W. Cheung; James P. Crane; Heidi A. Beaver; Ann C. Burgess
Prenatal Diagnosis | 1988
James P. Crane; Heidi A. Beaver; Sau W. Cheung
Prenatal Diagnosis | 1990
Sau W. Cheung; Edward L. Spitznagel; Terry Featherstone; James P. Crane
Prenatal Diagnosis | 1994
Terence Featherstone; Sau W. Cheung; Edward L. Spitznagel; David Peakman
Prenatal Diagnosis | 1988
Sau W. Cheung; Paula L. Kolacki; Michael S. Watson; James P. Crane
Prenatal Diagnosis | 1990
Sau W. Cheung; James P. Crane; Heidi A. Beaver
Prenatal Diagnosis | 1987
Sau W. Cheung; James P. Crane; Ann Johnson; Lyn Simms; Joan Reid