Shifat A Nowrin

Association between genetic polymorphisms and external apical root resorption: A systematic review and meta-analysis

Objective To date, only a few studies have investigated the relationships between genetic polymorphisms and external apical root resorption (EARR). Hence, the aim of this systematic review was to explore the relationship between different gene polymorphisms and their association with EARR. Methods A complete literature search was conducted by two independent reviewers. The PubMed, Science Direct, and Scopus databases were searched. In addition, the bibliographies of all textbooks and relevant articles were searched manually. A meta-analysis was performed using data entered into the electronic databases until February 28, 2017. Results On the basis of the search, we identified 17 and 7 publications for the systematic review and meta-analysis, respectively. Odds ratio (OR) was used to evaluate the association of the interleukin 1B (+3954) polymorphism and the risk of EARR. The overall OR from the studies was used to estimate the risk of EARR. However, no association was found and no publication bias was apparent for the risk of EARR in patients receiving orthodontic treatment. Conclusions More research on the relationship between gene polymorphism and EARR is necessary to determine better specificity of possible interactions.

Orthodontic treatment combination with auto transplantation for the management of impacted maxillary left lateral incisor and canine: an interdisciplinary approach.

Aims: For the orthodontic treatment of the complex cases, the interdisciplinary team work is of utmost importance, which leads to the predictable outcome with excellent treatment. The prime aim of this rare case report is to demonstrate the combined orthodontic-surgical-endodonticprosthodontic interdisciplinary management. Case Study Alam et al.; BJMMR, 4(3): 276-284, 2015; Article no.BJMMR.2015.449 277 Presentation of Case: This report describes the case of a 19 years old Malay male patient with the clinical problems of median diastema, mesio-buccally rotated maxillary left 1 st premolar, mild mandibular incisor crowding along with impacted maxillary left lateral incisor and canine. Discussion: With the advantages of the orthodontic fixed appliance, auto-transplantation of maxillary upper left lateral incisor and canine, the case was completed in an ideal orthodontic occlusion along with improved oral condition, masticatory function and esthetics. The treatment outcomes were due to orthodontic-surgical-endodontic-prosthodontic treatment with stable occlusion in sequels visits. Conclusion: An Interdisciplinary management achieved successful functional and esthetic results in the present case.