Shih-Ann Chen

Venice Chart International Consensus Document on Atrial Fibrillation Ablation

Venice Chart International Consensus Document on Atrial Fibrillation Ablation ANDREA NATALE, M.D.,∗ ANTONIO RAVIELE, M.D.,† THOMAS ARENTZ, M.D.,‡ HUGH CALKINS, M.D.,¶ SHIH-ANN CHEN, M.D.,∗∗ MICHEL HAISSAGUERRE, M.D.,†† GERHARD HINDRICKS, M.D.,‡‡ YEN HO, M.D.,¶¶ KARL HEINZ KUCK, M.D.,∗∗∗ FRANCIS MARCHLINSKI, M.D.,††† CARLO NAPOLITANO, M.D.,‡‡‡ DOUGLAS PACKER, M.D.,¶¶¶ CARLO PAPPONE, M.D.,∗∗∗∗ ERIC N. PRYSTOWSKY, M.D.,†††† RICHARD SCHILLING, M.D.,‡‡‡‡ DIPEN SHAH, M.D.,¶¶¶¶ SAKIS THEMISTOCLAKIS, M.D.,† and ATUL VERMA, M.D.,∗∗∗∗∗ for the Venice Chart members From the ∗Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, USA; †Department of Cardiology, Arrhythmologic Section, Umberto I Hospital, Venice-Mestre, Italy; ‡Arrhythmia Service, Herz-Zentrum, Bad Krozingen, Germany; ¶Department of Cardiology, The Johns Hopkins Hospital, Baltimore, USA; ∗∗Division of Cardiology, Department of Medicine, National Yang-Ming University School of Medicine and Taipei Veterans General Hospital, Taipei, Taiwan; ††Hospital du Haut Leveque, CHU Bordeaux, Bordeaux, France; ‡‡University Leipzig, Heart Center, Department of Cardiology, Leipzig, Germany; ¶¶National Heart and Lung Institute, Imperial College and Royal Brompton & Harefield Hospitals, London, UK; ∗∗∗Second Medical Department, St Georg General Hospital, Hamburg, Germany; †††Cardiovascular Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, USA; ‡‡‡Molecular Cardiology Laboratory, University of Pavia, Salvatore Maugeri Foundation, Pavia, Italy; ¶¶¶Department of Clinical Cardiac Electrophysiology and Internal Medicine, Mayo Clinic, Rochester, USA; ∗∗∗∗Department of Cardiology, Electrophysiology and Cardiac Pacing Unit, San Raffaele University Hospital, Milan, Italy; ††††St. Vincent Hospital and Health Care Center Program, Indianapolis, USA; ‡‡‡‡St. Bartholomew’s Hospital, London, UK; ¶¶¶¶Cardiology Cantonal Hospital of Geneva, Geneva, Switzerland; ∗∗∗∗∗University of Toronto, Toronto, Canada.

Double multielectrode mapping catheters facilitate radiofrequency catheter ablation of focal atrial fibrillation originating from pulmonary veins.

Ablation of Focal AF. Introduction: Several reports have demonstrated that focal atrial fibrillation (AF) may arise from pulmonary veins (PVs). The purpose of this study was to investigate the safety and efficacy of using double multielectrode mapping catheters in ablation of focal AF.

Electrophysiology of pulmonary veins

Pulmonary veins were found to be important foci for the genesis and maintenance of atrial fibrillation. Morphological studies have demonstrated the presence of complex anatomic structures and different types of cardiomyocytes in pulmonary veins. Numerous studies have suggested that the combination of reentrant and nonreentrant mechanisms (automaticity and triggered activity) are the underlying arrhythmogenic mechanisms of atrial fibrillation initiation from the pulmonary veins. Electropharmacological studies further indicated that pulmonary veins contained distinct arrhythmogenic activity. Several experimental models have been used to study the pulmonary vein electrical activity and demonstrate the precipitating factors for enhancing the pulmonary vein arrhythmogenic activity. The aim of this review article is to provide a critical overview of the current understanding of the basic and clinical electrophysiology of pulmonary veins and to underscore the importance of future research in this field.

Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone: Electrophysiologic characteristics, radiofrequency catheter ablation, and risk prediction

Antiarrhythmic Drug‐Related Atrial Flutter. introduction: Antiarrhythmic drugs have been reported to promote the conversion of atrial fibrillation to atrial flutter inn patients with paroxysmal atrial fibrillation. However, information about the electrophysiologic mechanism and response to radiofrequency ablation of these drug‐induced atrial flutters is limited. Furthermore, the determinants of the development of persistent atrial flutter in patients treated for atrial fibrillation with antiarrhythmic drugs are still unknown.

Electrophysiologic Characteristics and Radiofrequency Catheter Ablation in Patients with Clockwise Atrial Flutter

RF Catheter Ablation of Clockwise Atrial Flutter. introduction: Although the mechanism and radiofrequency catheter ablation of counterclockwise (typical) atrial flutter have been studied extensively, information about the electrocardiographic and electropbysiologic characteristics and effects of radiofrequency ablation in patients with clockwise atrial flutter is limited.

Dimension and Related Anatomical Distance of Koch's Triangle in Patients with Atrioventricular Nodal Reentrant Tachycardia

Kochs Triangle in AVNRT. Introduction: The dimension of Kochs triangle in patients with AV nodal reentrant tachycardia has not been well described. Understanding the dimension and anatomical distance related to Kochs triangle might be useful in avoiding accidental AV block during ablation of the slow pathway. The purposes of this study were to define the dimension of Kochs triangle and its related anatomical distance and correlate these parameters with the successful ablation sites in patients with AV nodal reentrant tachycardia.

Effects of 17β-Estradiol on Tachycardia-Induced Changes of Atrial Refractoriness and Cisapride-Induced Ventricular Arrhythmia

17β‐Estradiol and Arrhythmia. Introduction: Gender difference is known to be associated with the occurrence of arrhythmia. However, the effects of female sex hormone on atrial electrophysiology, and on the occurrence of torsades de pointes (TdP) induced by cisapride have been unclear.

T-Type Calcium Current in Electrical Activity of Cardiomyocytes Isolated from Rabbit Pulmonary Vein

Introduction: Pulmonary veins (PVs) are known to initiate paroxysmal atrial fibrillation. T‐type calcium current (ICa‐T) has a role in normal and abnormal automaticity of cardiomyocytes. The aim of this study was to evaluate whether ICa‐T contributes to PV electrical activity.

Heterogeneous expression of potassium currents and pacemaker currents potentially regulates arrhythmogenesis of pulmonary vein cardiomyocytes.

Introduction: The relationship between the determining factors and beating rates of pulmonary vein (PV) pacemaker cardiomyocytes has not been fully elucidated. The purposes of this study were to compare the electrophysiological characteristics between PV fast and slow pacemaker cardiomyocytes.

Electromechanical Effects of 1,25‐Dihydroxyvitamin D with Antiatrial Fibrillation Activities

Treatment with 1,25‐dihydroxyvitamin D (1,25[OH]2D) has several cardiovascular benefits. 1,25[OH]2D has direct cellular effects, but its effects on the atrium are not clear. We evaluated the effects of 1,25[OH]2D on the atrial electrophysiology and atrial fibrillation (AF).