Shyamala Rajagopalan

Synthesis of N-t-Boc-4-S-t-Butyl-L-thiophenylalanine via Palladium Catalyzed Cross-Coupling Reaction of N-t-Boc-4-Iodo-L-phenylalanine with t-Butylthiol or Sodium t-Butylthiolate

Abstract Cross-coupling reaction of N-t-Boc-4-iodo-L-phenylalanine with t-BuSH proceeded efficiently in the presence of Pd2dba3.CHCl3/DPPF as the catalyst system. However, Pd2dba3.CHCl3/DPPB was found to be more effective for coupling with t-BuSNa.

Nanostructured Materials: Industrial Applications

Nanoscience and nanotechnology are transforming materials science in a broad way, in a manner similar to polymer chemistry’s transformation of materials science over the preceding century. The continuous development of novel nanostructured materials and the extensive study of physicochemical phenomena at the nanoscale are creating new approaches to innovative technologies that are constantly resulting in products with a wide range of applications [1–5].

A Simple Procedure for the Preparation of 4-(α-Mercaptobenzyl)Phenoxyacetic Acid, A Thiol Linker Unit Used in Solid Phase Synthesis of Peptide-α-Thioacids

Abstract A convenient procedure for the preparation of the title compound via direct thionation of its alcohol precursor by Lawessons reagent is described.