Sigetosi Kamiyama
Tohoku University
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Environment International | 2011
Kouji H. Harada; Toshiaki Hitomi; Tamon Niisoe; Katsunobu Takanaka; Sigetosi Kamiyama; Takao Watanabe; Chan-Seok Moon; Hye-Ran Yang; Nguyen Ngoc Hung; Akio Koizumi
Perfluorooctanoic acid (PFOA) has recently attracted attention as a potential health risk following environmental contamination. However, information detailing exposure to perfluorinated carboxylic acids (PFCAs) other than PFOA is limited. We measured the concentrations of PFCAs (from perfluorohexanoic acid to perfluorotetradecanoic acid) in serum samples obtained from patients in Japan (Sendai, Takayama, Kyoto and Osaka) between 2002 and 2009, Korea (Busan and Seoul) between 1994 and 2008 and Vietnam (Hanoi) in 2007/2008. Total PFCA levels (geometric mean) were increased from 8.9 ng mL(-1) to 10.3 ng mL(-1) in Japan; from 7.0 ng mL(-1) to 9.2 ng mL(-1) in Korea; and were estimated at 4.7 ng mL(-1) in Vietnam. PFCAs of greater length than PFOA were significantly increased in Sendai, Takayama and Kyoto, Japan, and levels of long-chain PFCAs exceeded PFOA levels in serum. Among these PFCAs, perfluoroundecanoic acid (PFUnDA) was the predominant component (28.5%), followed by perfluorononanoic acid (PFNA 17.5%), perfluorodecanoic acid (PFDA 7.9%), perfluorotridecanoic acid (PFTrDA 6.1%) and perfluorododecanoic acid (PFDoDA 1.8%). Odd-numbered PFCAs (PFNA, PFUnDA and PFTrDA) were also observed in Korea and Vietnam and their presence increased significantly in Korea between 1994 and 2007/2008. The proportion of long-chain PFCAs in serum was relatively high compared to reports in Western countries. Further investigations into the sources and exposure routes are needed to predict the future trajectory of these serum PFCA levels.
Journal of the National Cancer Institute | 1982
Abraham M. Y. Nomura; Hiroshi Yamakawa; Takuzo Ishidate; Sigetosi Kamiyama; Hisayuki Masuda; Grant N. Stemmermann; Lance K. Heilbrun; Jean H. Hankin
Cancer Research | 1979
Howard F. Mower; Ralph M. Ray; Robert Shoff; Grant N. Stemmermann; Abraham M. Y. Nomura; Gary Glober; Sigetosi Kamiyama; Akio Shimada; Hiroshi Yamakawa
Cancer Research | 1982
Howard F. Mower; D. Ichinotsubo; L. W. Wang; M. Mandel; Stemmermann Gn; Abraham M. Y. Nomura; Lance K. Heilbrun; Sigetosi Kamiyama; Akio Shimada
Tohoku Journal of Experimental Medicine | 1972
Sigetosi Kamiyama; Satoru Kobayashi; Shoichi Abe; Eiji Takahashi; Eikichi Wakamatsu; Tatsuya Kurashina
Tohoku Journal of Experimental Medicine | 1955
Hajime Masamune; Sen-itiroh Hakomori; Haruo Numabe; Ziroh Akama; Sigetosi Kamiyama
Pharmacology & Toxicology | 1990
Jun-ichi Hasegawa; Yasuhiko Wada; Masato Sageshima; Masahiro Suzuki; Sigetosi Kamiyama; Nobuo Abe; Akio Koizumi
Tohoku Journal of Experimental Medicine | 1969
Sigetosi Kamiyama; Fumio Yamada; Satoru Kobayashi; Eiji Takahashi
Tohoku Journal of Experimental Medicine | 1968
Sigetosi Kamiyama; Satoru Kobayashi; Eiji Takahashi; Eikichi Wakamatsu; Tatsuya Kurashina
Tohoku Journal of Experimental Medicine | 1965
Sigetosi Kamiyama; Kozo Ishiguro; Yoshiaki Kawakami; Satoru Kobayashi; Fumio Yamada; Eiji Takahashi