g-Ee Son

Antimicrobial Activity of Sodium chlorate and Korean Herbal Extracts against Mice infected with Escherichia coli O157:H7

ABSTRACT - The present study was evaluated the antibacterial effect of the combination of Coptidis rhizoma,Glycyrrhiza uralensis Fischet, Schizandra chinensis and Corni Fructus(1:1:1) extracts(CGSC10). Furthermore, theeffectiveness of CGSC10, sodium chlorate, and the combination of CGSC10 and sodium chlorate(CGSCS10) againstE. coli O157:H7 infection was studied using ICR female mice. During the incubation period, the dose of 5, 10, and20% CGSC10 was inhibited the growth of E. coli O157:H7 by 34.7, 60.2, and 76.4%, respectively. For 7 days aftersingle challenge with E. coli O157:H7, forty female ICR mice were divided into four experimental groups which wereadministered in drinking water with saline, 10% CGSC10, 15 mM sodium chlorate, and CGSCS10, respectively. Onthe 3rd day, the number of E. coli O157:H7 in mouse feces was significantly decreased by administration of CGSC10,15 mM sodium chlorate, and CGSCS10 (p < 0.001). On the 7th day-after administration, CGSC10, sodium chlorate,and CGSCS10 were decreased the number of E. coli O157:H7 by 27.1, 67.7, and 83.3%, respectively. According tothe results of the present study, administration of CGSCS10 to mice can reduce the severity of E. coli O157:H7 infec-tion. In addition, it is suggested that CGSCS10 represents a good candidate for the treatment of enteric infections indomestic animals. Key words: Korean traditional herbal extracts, sodium chlorate, antibacterial activity, E. coli O157:H7

Antimicrobial Efficacies of Citra-Kill ® , Disinfectant Solution against Salmonella Typhimurium and Brucella Ovis

Salmonellosis and brucellosis have caused a considerable danger of farmed animals and economic loss in animal farming industry. In this study, the disinfection efficacy of Citra-Kill ® , a commercial disinfectant, composed to quaternary ammonium chloride and citric acid was evaluated against S. typhimurium and Brucella ovis. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of the disinfectant following exposure to test bacteria for 30 min at 4℃. Citra-Kill ® and test bacteria were diluted with distilled water (DW), hard water (HW) or organic matter suspension (OM) according to treatment condition. On OM condition, the bactericidal activity of Citra-Kill ® against S. typhimurium and Brucella ovis was lowered compared to that on HW condition. As Citra-Kill ® possesses bactericidal efficacy against animal pathogenic bacteria such as S. typhimurium and Brucella ovis, this disinfectant solution can be used to control the spread of animal bacterial diseases.

Bactericidal Efficacy of a Fumigation Disinfectant Containing Paraformaldehyde Against Salmonella Typhimurium

본 연구는 S. Typhimurium을 대상으로 paraformaldehyde 35%를 함유한 훈증소독제의 살균효과를 평가하기 위해 수행되었다. 예비 시험에서, S. Typhimurium의 현탁액 균수는 모두

Therapeutic effect of oregano essential oil on subclinical bovine mastitis caused by Staphylococcus aureus and Escherichia coli

3.9{\times}10^8CFU/mL

Effects of reduced glutathione on stress and inflammatory response in Korean native calves vaccinated with foot-and-mouth disease vaccine

이었으며, 훈증소독제에 노출시킨 모든 담체의 균수는 평판배지법과 여과법으로 배양한 시험균주 현탁액의 균수의 ...