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Featured researches published by Srinivas Marmamula.


BMJ Open | 2011

Population-based cross-sectional study of barriers to utilisation of refraction services in South India: Rapid Assessment of Refractive Errors (RARE) Study.

Srinivas Marmamula; Jill E. Keeffe; Usha Raman; Gullapalli N. Rao

Aim To assess the barriers to the uptake of refraction services in the age group of 15–49 years in rural Andhra Pradesh, India. Methods A population-based cross-sectional study was conducted using cluster random sampling to enumerate 3300 individuals from 55 clusters. A validated questionnaire was used to elicit information on barriers to utilisation of services among individuals with uncorrected refractive error (presenting visual acuity <6/12 but improving to ≥6/12 on using a pinhole) and presbyopia (binocular near vision 35 years with binocular distance visual acuity of ≥6/12). Results 3095 (94%) were available for examination. Those with uncorrected refractive errors cited affordability as the main barrier to the uptake of eye-care services. Among people with uncorrected presbyopia, lack of ‘felt need’ was the leading barrier. Conclusion The barriers that were ‘relatively easy to change’ were reported by those with uncorrected refractive errors in contrast to ‘difficult to change’ barriers reported by those with uncorrected presbyopia. Together, the data on prevalence and an understanding of the barriers for the uptake of services are critical to the planning of refractive error services.


Ophthalmic Epidemiology | 2009

Uncorrected refractive errors, presbyopia and spectacle coverage: results from a rapid assessment of refractive error survey.

Srinivas Marmamula; Jill E. Keeffe; Gullapalli N. Rao

PURPOSE To investigate the prevalence of uncorrected refractive errors, presbyopia and spectacle coverage in subjects aged 15-50 years using rapid assessment methodology in the Mahabubnagar district of Andhra Pradesh, India. METHODS A population-based cross sectional study was conducted using cluster random sampling to enumerate 3,300 subjects from 55 clusters. Unaided, aided and pinhole visual acuity was assessed using a LogMAR chart at a distance of 4 meters. Near vision was assessed using N notation chart. Uncorrected refractive error was defined as presenting visual acuity worse than 6/12 but improving to at least 6/12 or better on using a pinhole. Presbyopia is defined as binocular near vision worse than N8 in subjects aged more than 35 years with binocular distance visual acuity of 6/12 or better. RESULTS Of the 3,300 subjects enumerated from 55 clusters, 3,203 (97%) subjects were available for examination. Of these, 1,496 (46.7%) were females and 930 (29%) were > or = 40 years. Age and gender adjusted prevalence of uncorrected refractive errors causing visual impairment in the better eye was 2.7% (95% CI, 2.1-3.2%). Presbyopia was present in 690 (63.7%, 95% CI, 60.8-66.6%) subjects aged over 35 years. Spectacle coverage for refractive error was 29% and for presbyopia it was 19%. CONCLUSIONS There is a large unmet need for refractive correction in this area in India. Rapid assessment methods are an effective means of assessing the need for services and the impact of models of care.


Investigative Ophthalmology & Visual Science | 2013

Population-based assessment of prevalence and risk factors for pterygium in the South Indian state of Andhra Pradesh: the Andhra Pradesh Eye Disease Study.

Srinivas Marmamula; Rohit C Khanna; Gullapalli N. Rao

PURPOSE To describe the prevalence and risk factors for pterygium in a population-based sample of individuals aged 30 years and older in South Indian state of Andhra Pradesh. METHODS A cross-sectional study was conducted in one urban and three rural locations in which 10,293 subjects were examined. All the subjects underwent comprehensive eye examination and a detailed interview by trained professionals. Pterygium was defined as fleshy fibro vascular growth, crossing the limbus, and typically seen on the nasal conjunctiva in either eye. RESULTS Data were analyzed for 5586 subjects who were aged 30 years and older at the time of participation. The mean age of the participants was 47.5 years (SD 13 years; range 30-102 years). In total, 46.4% were male, 56.7% had no education, 52.2% of them were involved in outdoor occupations, and 25% belonged to urban area. The prevalence of pterygium was 11.7% (95% confidence interval [CI]: 10.9-12.6). The multiple logistic regression analysis revealed significantly higher odds of pterygium among older age groups, rural residents (odds ratio [OR]: 1.8; 95% CI: 1.4-2.4; P > 0.01), and those involved in outdoor occupations (OR: 1.8; 95% CI: 1.5-2.2, P < 0.001). Education had a protective effect (OR: 0.6; 95% CI: 0.5-0.7; P < 0.001). CONCLUSIONS Pterygium is common in the South Indian state of Andhra Pradesh. Exposure to sunlight is a significant modifiable risk factor. Protecting the eyes from sunlight may decrease the risk of pterygium. However, the important public health challenge is to encourage the use of this protection as a routine in developing countries such as India.


PLOS ONE | 2013

Visual Impairment in the South Indian State of Andhra Pradesh: Andhra Pradesh - Rapid Assessment of Visual Impairment (AP-RAVI) Project

Srinivas Marmamula; Saggam Narsaiah; Konegari Shekhar; Rohit C Khanna; Gullapalli N. Rao

Purpose To assess the prevalence and causes of visual impairment in urban and rural population aged ≥40 years in the South India state of Andhra Pradesh. Methods A population based cross-sectional study was conducted in which 7800 subjects were sampled from two rural and an urban locations. Visual Acuity (VA) was assessed using a tumbling E chart and eye examinations were performed by trained vision technicians. A questionnaire was used to collect personal and demographic information and previous consultation to eye care providers. Blindness and moderate Visual Impairment (VI) was defined as presenting VA <6/60 and <6/18 to 6/60 in the better eye respectively. VI included blindness and moderate VI. Results Of the 7800 subjects enumerated, 7378 (94.6%) were examined. Among those examined, 46.4% were male and 61.8% of them had no education. The mean age of those examined (51.7 years; standard deviation 10.9 years) was similar to those not examined (52.8 years; standard deviation 9.9 years) (p = 0.048). Age and gender adjusted prevalence of VI was 14.3% (95% CI: 13.5–15.0). Refractive errors were the leading cause of VI accounting for 47.6% of all VI followed by cataract (43.7%). Together, they contributed to over 91.3% of the total VI. With multiple logistic regression, the odds of having VI increased significantly with increasing age. Those respondents who had no education were twice (95% CI: 1.7–2.5) more likely to have VI compared to those who were educated. VI was associated with rural residence (OR: 1.3; 95% CI: 1.1–1.6). The association between VI and gender was not statistically significant. Conclusions The visual impairment remains a public health challenge in Andhra Pradesh, most of which can be addressed with relatively straight forward interventions like cataract surgery and spectacles. The eye care services need to be streamlined to address this challenge.


BMC Ophthalmology | 2011

Rapid assessment of visual impairment (RAVI) in marine fishing communities in South India--study protocol and main findings.

Srinivas Marmamula; Sreenivas R Madala; Gullapalli N. Rao

BackgroundReliable data are a pre-requisite for planning eye care services. Though conventional cross sectional studies provide reliable information, they are resource intensive. A novel rapid assessment method was used to investigate the prevalence and causes of visual impairment and presbyopia in subjects aged 40 years and older. This paper describes the detailed methodology and study procedures of Rapid Assessment of Visual Impairment (RAVI) project.MethodsA population-based cross-sectional study was conducted using cluster random sampling in the coastal region of Prakasam district of Andhra Pradesh in India, predominantly inhabited by fishing communities. Unaided, aided and pinhole visual acuity (VA) was assessed using a Snellen chart at a distance of 6 meters. The VA was re-assessed using a pinhole, if VA was < 6/12 in either eye. Near vision was assessed using N notation chart binocularly. Visual impairment was defined as presenting VA < 6/18 in the better eye. Presbyopia is defined as binocular near vision worse than N8 in subjects with binocular distance VA of 6/18 or better.ResultsThe data collection was completed in <12 weeks using two teams each consisting of one paramedical ophthalmic personnel and two community eye health workers. The prevalence of visual impairment was 30% (95% CI, 27.6-32.2). This included 111 (7.1%; 95% CI, 5.8-8.4) individuals with blindness. Cataract was the leading cause of visual impairment followed by uncorrected refractive errors. The prevalence of blindness according to WHO definition (presenting VA < 3/60 in the better eye) was 2.7% (95% CI, 1.9-3.5).ConclusionThere is a high prevalence of visual impairment in marine fishing communities in Prakasam district in India. The data from this rapid assessment survey can now be used as a baseline to start eye care services in this region. The rapid assessment methodology (RAVI) reported in this paper is robust, quick and has the potential to be replicated in other areas.


Ophthalmic and Physiological Optics | 2012

Prevalence of uncorrected refractive errors, presbyopia and spectacle coverage in marine fishing communities in South India: Rapid Assessment of Visual Impairment (RAVI) project

Srinivas Marmamula; Sreenivas R Madala; Gullapalli N. Rao

Citation information: Marmamula S, Madala SR & Rao GN. Prevalence of uncorrected refractive errors, presbyopia and spectacle coverage in marine fishing communities in South India: Rapid Assessment of Visual Impairment (RAVI) project. Ophthalmic Physiol Opt 2012, 32, 149–155. doi: 10.1111/j.1475‐1313.2012.00893.x


Indian Journal of Ophthalmology | 2012

Rapid assessment methods in eye care: an overview.

Srinivas Marmamula; Jill E. Keeffe; Gullapalli N. Rao

Reliable information is required for the planning and management of eye care services. While classical research methods provide reliable estimates, they are prohibitively expensive and resource intensive. Rapid assessment (RA) methods are indispensable tools in situations where data are needed quickly and where time- or cost-related factors prohibit the use of classical epidemiological surveys. These methods have been developed and field tested, and can be applied across almost the entire gamut of health care. The 1990s witnessed the emergence of RA methods in eye care for cataract, onchocerciasis, and trachoma and, more recently, the main causes of avoidable blindness and visual impairment. The important features of RA methods include the use of local resources, simplified sampling methodology, and a simple examination protocol/data collection method that can be performed by locally available personnel. The analysis is quick and easy to interpret. The entire process is inexpensive, so the survey may be repeated once every 5–10 years to assess the changing trends in disease burden. RA survey methods are typically linked with an intervention. This article provides an overview of the RA methods commonly used in eye care, and emphasizes the selection of appropriate methods based on the local need and context.


Indian Journal of Ophthalmology | 2012

Changing trends in the prevalence of blindness and visual impairment in a rural district of India: systematic observations over a decade.

Rohit C Khanna; Srinivas Marmamula; Sannapaneni Krishnaiah; Pyda Giridhar; Subhabrata Chakrabarti; Gullapalli N. Rao

Context: Globally, limited data are available on changing trends of blindness from a single region. Aims: To report the changing trends in the prevalence of blindness, visual impairment (VI), and visual outcomes of cataract surgery in a rural district of Andhra Pradesh, India, over period of one decade. Settings and Design: Rural setting; cross-sectional study. Materials and Methods: Using a validated Rapid Assessment of Cataract Surgical Services (RACSS) method, population-based, cross-sectional survey was done in a rural district in the state of Andhra Pradesh, India. Two-stage sampling procedure was used to select participants ≥50 years of age. Further, a comparative analysis was done with participants ≥50 years from the previously concluded Andhra Pradesh Eye Disease Study (APEDS) study, who belonged to the same district. Statistical Analysis: Done using 11th version of Stata. Results: Using RACSS, 2160/2300 (93.9%) participants were examined as compared with the APEDS dataset (n=521). Age and sex adjusted prevalence of blindness in RACSS and APEDS was 8% (95% CI, 6.9–9.1%) and 11% (95% CI, 8.3–13.7%), while that of VI was 13.6% (95% CI, 12.2–15.1%) and 40.3% (95% CI, 36.1–44.5%), respectively. Cataract was the major cause of blindness in both the studies. There was a significant reduction in blindness following cataract surgery as observed through RACSS (17.3%; 95% CI, 13.5–21.8%) compared with APEDS (34%; 95% CI, 20.9–49.3%). Conclusion: There was a significant reduction in prevalence of blindness and VI in this rural district of India over a decade.


BMJ Open | 2014

A population-based cross-sectional study of barriers to uptake of eye care services in South India: the Rapid Assessment of Visual Impairment (RAVI) project

Srinivas Marmamula; Rohit C Khanna; Konegari Shekhar; Gullapalli N. Rao

Objective To assess the barriers to uptake of eye care services among those with avoidable impairment in the population aged ≥40 years in the South Indian state of Andhra Pradesh. Design Cross-sectional study. Setting Community setting. Participants Of 7800 participants recruited from one urban and two rural locations using a two-stage cluster random sampling methodology, 7378 (95%) were examined. Eye examinations were conducted using a rapid assessment protocol. Visual impairment (VI) was defined as presenting visual acuity <6/18 in the better eye. For the purpose of this study, VI caused due to cataract or uncorrected refractive error was considered avoidable VI. A validated questionnaire was used to collect information on barriers for uptake of services among those who had avoidable VI. Primary outcome Barriers to uptake of services among those with avoidable VI. Results The prevalence of avoidable VI was 11.8% (95% CI 11.0% to 12.5%; n=868). Among these, 71.1% (n=617) individuals reported ‘person-related’ barriers whereas 28.9% (n=251) individuals reported ‘service-related’ barriers to uptake of services. Among the ‘person-related’ barriers, the leading barrier was ‘lack of perceived need’ (61.1%; n=377) for reasons such as old age, good vision in the other eye. This was followed by ‘no one to accompany’ (20.3%; n=125). Of the 251 individuals who had ‘service-related’ barriers, lack of affordability was the major barrier (76.1%; n=191) followed by lack of accessibility (12.7%; n=32). Over 11% (n=28) of the individuals were advised to wait for cataract surgery. Conclusions Person-related barriers are more common than service-related barriers in Andhra Pradesh. As the barriers trend more towards ‘person-related’ phenomenon such as persons attitude and ‘felt need’ to improve vision, newer and much intensive awareness campaigns are needed to bring about an attitudinal/behavioural change among individuals to improve the uptake of services.


Ophthalmic and Physiological Optics | 2013

Presbyopia, spectacles use and spectacle correction coverage for near vision among cloth weaving communities in Prakasam district in South India

Srinivas Marmamula; Saggam Narsaiah; Konegari Shekhar; Rohit C Khanna

To assess the prevalence of presbyopia, spectacles use and spectacle correction coverage for near vision among weaving communities in Prakasam district in the South Indian state of Andhra Pradesh.

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Rohit C Khanna

L V Prasad Eye Institute

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Jill E. Keeffe

L V Prasad Eye Institute

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Pyda Giridhar

L V Prasad Eye Institute

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Seema Banerjee

L V Prasad Eye Institute

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