Stefano I. Di Domenico

A problem-solving task specialized for functional neuroimaging: validation of the Scarborough adaptation of the Tower of London (S-TOL) using near-infrared spectroscopy

Problem-solving is an executive function subserved by a network of neural structures of which the dorsolateral prefrontal cortex (DLPFC) is central. Whereas several studies have evaluated the role of the DLPFC in problem-solving, few standardized tasks have been developed specifically for use with functional neuroimaging. The current study adapted a measure with established validity for the assessment of problem-solving abilities to design a test more suitable for functional neuroimaging protocols. The Scarborough adaptation of the Tower of London (S-TOL) was administered to 38 healthy adults while hemodynamic oxygenation of the PFC was measured using 16-channel continuous-wave functional near-infrared spectroscopy (fNIRS). Compared to a baseline condition, problems that required two or three steps to achieve a goal configuration were associated with higher activation in the left DLPFC and deactivation in the medial PFC. Individuals scoring higher in trait deliberation showed consistently higher activation in the left DLPFC regardless of task difficulty, whereas individuals lower in this trait displayed less activation when solving simple problems. Based on these results, the S-TOL may serve as a standardized task to evaluate problem-solving abilities in functional neuroimaging studies.

Differentiating functions of the lateral and medial prefrontal cortex in motor response inhibition

The right inferior frontal gyrus is generally considered a critical region for motor response inhibition. Recent studies, however, suggest that the role of this cortical area in response inhibition may be overstated and that the contributions of other aspects of the prefrontal cortex are often overlooked. The current study used optical imaging to identify regions of the prefrontal cortex beyond the right inferior frontal gyrus which may serve to support motor response inhibition. Forty-three right-handed healthy adults completed a manual Go/No-Go task while evoked oxygenation of the prefrontal cortex was measured using 16-channel functional near-infrared spectroscopy. During motor response inhibition, the right inferior frontal gyrus, and to a lesser extent the homologous contralateral region, showed increased activation relative to a baseline task. Conversely, the medial prefrontal cortex was significantly deactivated, and the extent of reduced activity in this region was associated with fewer errors on the response inhibition task. These findings suggest a more substantial role of the left inferior frontal gyrus in response inhibition and possibly a distinct function of the middle frontal gyrus subserving error detection on manual motor control tasks.

The Emerging Neuroscience of Intrinsic Motivation: A New Frontier in Self-Determination Research

Intrinsic motivation refers to people’s spontaneous tendencies to be curious and interested, to seek out challenges and to exercise and develop their skills and knowledge, even in the absence of operationally separable rewards. Over the past four decades, experimental and field research guided by self-determination theory (SDT; Ryan and Deci, 2017) has found intrinsic motivation to predict enhanced learning, performance, creativity, optimal development and psychological wellness. Only recently, however, have studies begun to examine the neurobiological substrates of intrinsic motivation. In the present article, we trace the history of intrinsic motivation research, compare and contrast intrinsic motivation to closely related topics (flow, curiosity, trait plasticity), link intrinsic motivation to key findings in the comparative affective neurosciences, and review burgeoning neuroscience research on intrinsic motivation. We review converging evidence suggesting that intrinsically motivated exploratory and mastery behaviors are phylogenetically ancient tendencies that are subserved by dopaminergic systems. Studies also suggest that intrinsic motivation is associated with patterns of activity across large-scale neural networks, namely, those that support salience detection, attentional control and self-referential cognition. We suggest novel research directions and offer recommendations for the application of neuroscience methods in the study of intrinsic motivation.

Basic psychological needs and neurophysiological responsiveness to decisional conflict: an event-related potential study of integrative self processes.

Fulfillment of the basic psychological needs for competence, relatedness, and autonomy is believed to facilitate people’s integrative tendencies to process psychological conflicts and develop a coherent sense of self. The present study therefore used event-related potentials (ERPs) to examine the relation between need fulfillment and the amplitude of conflict negativity (CN), a neurophysiological measure of conflict during personal decision making. Participants completed a decision-making task in which they made a series of forced choices according to their personal preferences. Three types of decision-making situations were created on the basis of participants’ unique preference ratings, which were obtained prior to ERP recording: low-conflict situations (choosing between an attractive and an unattractive option), high-conflict approach-approach situations (choosing between two similarly attractive options), and high-conflict avoidance-avoidance situations (choosing between two similarly unattractive options). As expected, CN amplitudes were larger in high- relative to low-conflict situations, and source localization analyses suggested that the anterior cingulate cortex was the generating structure of the CN. Most importantly, people reporting higher need fulfillment exhibited larger CN amplitudes in avoidance–avoidance situations relative to low-conflict situations; to a lesser extent, they also exhibited larger CN amplitudes in approach–approach situations relative to low-conflict situations. By contrast, people reporting lower need fulfillment exhibited CN amplitudes that poorly discriminated the three decision situations. These results suggest that need fulfillment may promote self-coherent functioning by increasing people’s receptivity to and processing of events that challenge their abilities to make efficient, self-congruent choices.

Linking trait-based phenotypes to prefrontal cortex activation during inhibitory control

Inhibitory control is subserved in part by discrete regions of the prefrontal cortex whose functionality may be altered according to specific trait-based phenotypes. Using a unified model of normal range personality traits, we examined activation within lateral and medial aspects of the prefrontal cortex during a manual go/no-go task. Evoked hemodynamic oxygenation within the prefrontal cortex was measured in 106 adults using a 16-channel continuous-wave functional near-infrared spectroscopy system. Within lateral regions of the prefrontal cortex, greater activation was associated with higher trait levels of extraversion, agreeableness and conscientiousness, and lower neuroticism. Higher agreeableness was also related to more activation in the medial prefrontal cortex during inhibitory control. These results suggest that personality traits reflecting greater emotional stability, extraversion, agreeableness and conscientiousness may be associated with more efficient recruitment of control processes subserved by lateral regions of the prefrontal cortex. These findings highlight key links between trait-based phenotypes and neural activation patterns in the prefrontal cortex underlying inhibitory control.

Need fulfillment and the modulation of medial prefrontal activity when judging remembered past, perceived present, and imagined future identities

Abstract People’s abilities to integrate temporally distant identities are known to be facilitated by the fulfillment of basic psychological needs. However, the neural systems that support the integrative functions of need fulfillment are not well understood. Neuroimaging studies indicate that the medial prefrontal cortex (MPFC) differentiates remembered past, perceived present, and imagined future identities, possibly on the basis of the self-relevance attributed to specific identity representations. Using optical neuroimaging, we examined the relationship between need fulfillment and activity within the MPFC when young adults (N = 110) made trait judgments about their past, present, and future identities. Participants reporting higher need fulfillment evidenced similarly high levels of activity in the right-MPFC across the conditions; in contrast, those reporting lower need fulfillment evidenced markedly reduced activity when judging past and future identities. Results thus suggest that, among people who experience higher need fulfillment, the MPFC processes temporally distant identities in a similarly self-relevant manner. These findings provide a new type of evidence of the relationship between need fulfillment and identity integration and provide future studies with a point of entry for further examining the neural basis of identity integration.

The Signs and Significance of Personality Coherence in Personal Stories and Strivings

The concept of personality coherence refers to the extent of psychological unity and wholeness embodied within each individual. In the present research, we examined the extent to which the narrative, functional, and organismic conceptualizations of personality coherence interrelate, as well as their associations with psychological abilities and personal adjustment. College students (N = 391) narrated accounts of three personal memories; listed five personal strivings that they subsequently compared and evaluated; completed performance measures of their intelligence, wisdom, and creativity; and rated their hedonic and eudaimonic well-being. Individuals who coherently organized their autobiographical memories were protected against feeling pressured or compelled in their personal strivings and against being steered toward need-detracting futures. Narrative indicators of coherence were otherwise independent of the functional and organismic indicators, although all indicators of personality coherence correlated with personal adjustment. Wisdom and creativity predicted narrative coherence, which partially mediated the associations they demonstrated with eudaimonic well-being.

Development and Validation of Research Scales for the Leadership Multi‐rater Assessment of Personality (LMAP)

This article presents large-sample developmental and validation research for a set of research scales of an existing 360-degree personality measure, the LMAP 360 (Leadership Multi-rater Assessment of Personality). In Study 1 (N = 1,771), we identified 6 broad domains underlying LMAP item clusters: Neuroticism, Dominance, Enthusiasm, Openness, Agreeableness, and Conscientiousness. Scales measuring these broad domains and their constituent facets showed strong internal consistency, inter-rater reliability, and self-informant correlations. In Study 2 (N = 729 and N = 694), we examined LMAP research scales’ convergent and discriminant validity against three well-validated personality inventories (Goldbergs adjectives, the Big Five Inventory, and the Big Five Aspects Scales) and one measure of cognitive ability (the International Cognitive Ability Resource). LMAP research scales correlated strongly with corresponding scales from other inventories and were distinct from cognitive ability.

Hierarchy Formation and Self-Determination

We examined how self-determination, the subjective experience of one’s behavior as internally initiated and personally endorsed, depends on one’s standing in real-world social hierarchies. We predicted that those with the traits most relevant to status attainment would be those afforded the most opportunities to be self-determining. We examined the trait of physical attractiveness, given its documented association with social status and no known association with self-determination. First-year undergraduates living in same-sex residences rated their housemates’ social status, while an independent set of observers rated the participants’ physical attractiveness. Consistent with prediction, physically attractive individuals attained the highest levels of social status; in turn, those who attained the highest levels of social status experienced the highest levels of self-determination. These findings provide new insights into self-determination as an inherently relational phenomenon and specifically highlight the formative influence of social status on people’s capacities for self-determination.