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Dive into the research topics where Stephen J. Box is active.

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Featured researches published by Stephen J. Box.


Journal of The Chemical Society, Chemical Communications | 1987

The isolation and characterisation of (3R,5R)- and (3S,5R)-carbapenam-3-carboxylic acid from Serratia and Erwinia species and their putative biosynthetic role

Barrie W. Bycroft; Christopher Maslen; Stephen J. Box; Allan G. Brown; John W. Tyler

Two new β-lactams (4b) and (5b), and (3S,5R)-carbapenam-3-carboxylic acid, have been isolated from strains of Serratia and Erwinia spp.; their possible role, and that of (5R)-carbapen-2-em-3-carboxylic acid as intermediates in the biosynthesis of the more complex members of the carbapenem family of β-lactam antibiotics is discussed.


The Journal of Antibiotics | 1988

The biosynthetic implications of acetate and glutamate incorporation into (3R,5R)-carbapenam-3-carboxylic acid and (5R)-carbapen-2-em-3-carboxylic acid by Serratia sp.

Barrie W. Bycroft; Christopher Maslen; Stephen J. Box; Allan G. Brown; John W. Tyler


The Journal of Antibiotics | 1983

MM 14201, A NEW EPOXYQUINONE DERIVATIVE WITH ANTIBACTERIAL ACTIVITY PRODUCED BY A SPECIES OF STREPTOMYCES

Stephen J. Box; Martin L. Gilpin; Michael N. Gwynn; G. Hanscomb; Simon R. Spear; Allan G. Brown


The Journal of Antibiotics | 1990

MM 47761 and MM 49721, glycopeptide antibiotics produced by a new strain of Amycolatopsis orientalis : isolation, purification and structure determination

Stephen J. Box; Anna L. Elson; Martin L. Gilpin; David J. Winstanley


The Journal of Antibiotics | 1995

27-O-Demethylrapamycin, an Immunosuppressant Compound Produced by a New Strain of Streptomyces hygroscopicus

Stephen J. Box; Peter R. Shelley; John W. Tyler; Michael S. Verrall; Stephen R. Warr; Alison M. Badger; Mark Alan Levy; Rhona Mary Banks


The Journal of Antibiotics | 1989

MM 47755, A NEW BENZ[a]ANTHRACENE ANTIBIOTIC FROM A STREPTOMYCETE

Martin L. Gilpin; James Balchin; Stephen J. Box; John W. Tyler


The Journal of Antibiotics | 1983

PROPERTIES OF MM 13902 AND OTHER CARBAPENEM ANTIBIOTICS IN VITRO AND IN VIVO

Michael J. Basker; R. J. Boon; Stephen J. Box; E. A. Prestige; G. M. Smith; Simon R. Spear


The Journal of Antibiotics | 1988

NEW QUINONE ANTIBIOTICS OF THE GRANATICIN TYPE, ISOLATED FROM STREPTOMYCES LATERITIUS

Martin L. Gilpin; Stephen J. Box; Anna L. Elson


The Journal of Antibiotics | 1982

A new olivanic acid derivative produced by Streptomyces olivaceus: isolation and structural studies.

Stephen J. Box; D. F. Corbett; K. G. Robins; S. R. Spear; M. S. Verrall


The Journal of Antibiotics | 1988

MM 42842, a new member of the monobactam family produced by Pseudomonas cocovenenans. II: Production, isolation and properties of MM 42842

Stephen J. Box; Allan G. Brown; Martin L. Gilpin; Michael N. Gwynn; Simon R. Spear

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Allan G. Brown

Royal College of Science and Technology

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