Sumitsugu Kisanuki | Researchain

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Featured researches published by Sumitsugu Kisanuki.

Chemical & Pharmaceutical Bulletin | 1992

Kynostatin (KNI)-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine.

Tsutomu Mimoto; Junya Imai; Sumitsugu Kisanuki; Hiroshi Enomoto; Naoko Hattori; Kenichi Akaji; Yoshiaki Kiso

Chemical & Pharmaceutical Bulletin | 1991

KNI-102, a novel tripeptide HIV protease inhibitor containing allophenylnorstatine as a transition-state mimic.

Tsutomu Mimoto; Junya Imai; Shigeki Tanaka; Naoko Hattori; Sumitsugu Kisanuki; Kenichi Akaji; Yoshiaki Kiso

Chemical & Pharmaceutical Bulletin | 1991

Rational design and synthesis of a novel class of active site-targeted HIV protease inhibitors containing a hydroxymethylcarbonyl isostere. Use of phenylnorstatine or allophenylnorstatine as a transition-state mimic

Tsutomu Mimoto; Junya Imai; Shigeki Tanaka; Naoko Hattori; Osamu Takahashi; Sumitsugu Kisanuki; Yuichi Nagano; Makoto Shintani; Hideya Hayashi; Hiroshi Sakikawa; Kenichi Akaji; Yoshiaki Kiso

Chemical & Pharmaceutical Bulletin | 2000

Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere

Tsutomu Mimoto; Naoko Hattori; Haruo Takaku; Sumitsugu Kisanuki; Tominaga Fukazawa; Keisuke Terashima; Ryohei Kato; Satoshi Nojima; Satoru Misawa; Takamasa Ueno; Junya Imai; Hiroshi Enomoto; Shigeki Tanaka; Hiroshi Sakikawa; Makoto Shintani; Hideya Hayashi; Yoshiaki Kiso

Archive | 1993

Process for producing peptide derivatives and salts therefor

Tsutomu Mimoto; Sumitsugu Kisanuki; Osamu Takahashi; Yoshiaki Kiso

Biopharmaceutics & Drug Disposition | 1993

Comparison of a new orally potent tripeptide HIV-1 protease inhibitor (anti-AIDS drug) based on pharmacokinetic characteristics in rats after intravenous and intraduodenal administrations.

A. Kiriyama; Tsutomu Mimoto; Sumitsugu Kisanuki; Yoshiaki Kiso; Kanji Takada

Archive | 1993

Structure-activity relationships of HIV protease inhibitors containing allophenylnorstatine as a transition-state mimic

Sumitsugu Kisanuki; Tsutomu Mimoto; Junya Imai; Hiroshi Enomoto; Naoko Hattori; Osamu Takahashi; Ryohei Katoh; Shigeki Tanaka; Hiroshi Sakikawa; Tooru Kimura; Kenichi Akaji; Yoshiaki Kiso

Archive | 1993