Sushant Malhotra
Eli Lilly and Company
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Publication
Featured researches published by Sushant Malhotra.
Bioorganic & Medicinal Chemistry Letters | 2003
Thomas A. Engler; Kelly Wayne Furness; Sushant Malhotra; Concha Sanchez-Martinez; Chuan Shih; Walter Xie; Guoxin Zhu; Xun Zhou; Scott Eugene Conner; Margaret M. Faul; Kevin A. Sullivan; Stanley P. Kolis; Harold B. Brooks; Bharvin Patel; Richard M. Schultz; Tammy B. DeHahn; Kashif Kirmani; Charles D. Spencer; Scott A. Watkins; Eileen L. Considine; Jack Dempsey; Catherine A. Ogg; Nancy B. Stamm; Bryan D. Anderson; Robert M. Campbell; Vasu Vasudevan; Michelle L. Lytle
The synthesis and CDK inhibitory properties of a series of indolo[6,7-a]pyrrolo[3,4-c]carbazoles is reported. In addition to their potent CDK activity, the compounds display antiproliferative activity against two human cancer cell lines. These inhibitors also effect strong G1 arrest in these cell lines and inhibit Rb phosphorylation at Ser780 consistent with inhibition of cyclin D1/CDK4.
Tetrahedron Letters | 2003
Thomas A. Engler; Kelly Wayne Furness; Sushant Malhotra; Clive Gideon Diefenbacher; Joshua Ryan Clayton
Abstract Treatment of heteroaryl-aldehydes with diethyl cyanophosphonate in the presence of a catalytic amount of LiCN affords phosphorylated cyanohydrins which are reduced in situ with SmI 2 to give heteroaryl-acetonitriles in generally good overall yields (50–100%). The generality of the process is demonstrated.
Journal of Medicinal Chemistry | 2004
Thomas A. Engler; James Robert Henry; Sushant Malhotra; Brian Eugene Cunningham; Kelly Wayne Furness; Joseph T. Brozinick; Timothy Paul Burkholder; Michael P. Clay; Joshua Ryan Clayton; Clive Gideon Diefenbacher; Eric Hawkins; Philip W. Iversen; Yihong Li; Terry D. Lindstrom; Angela Lynn Marquart; Johnathan Alexander Mclean; David Mendel; Elizabeth A. Misener; Daniel A. Briere; John O'Toole; Warren J. Porter; Steven Queener; Jon K. Reel; Rebecca A. Owens; Richard A. Brier; Thomas E. Eessalu; Jill R. Wagner; and Robert M. Campbell; Renee Vaughn
Bioorganic & Medicinal Chemistry Letters | 2005
Thomas A. Engler; Sushant Malhotra; Timothy Paul Burkholder; James Robert Henry; David Mendel; Warren J. Porter; Kelly Wayne Furness; Clive Gideon Diefenbacher; Angela Lynn Marquart; Jon K. Reel; Yihong Li; Joshua Ryan Clayton; Brian Eugene Cunningham; Johnathan Alexander Mclean; John C. O’Toole; Joseph T. Brozinick; Eric Hawkins; Elizabeth A. Misener; Daniel A. Briere; Richard A. Brier; Jill R. Wagner; Robert M. Campbell; Bryan D. Anderson; Renee Vaughn; Donald B. Bennett; Timothy I. Meier; James A. Cook
Archive | 2003
Brian R. Berridge; Joshua Ryan Clayton; Clive Gideon Diefenbacher; Thomas A. Engler; Kelly Wayne Furness; James Robert Henry; Sushant Malhotra; Angela Lynn Marquart; Johnathan Alexander Mclean; David Mendel; Timothy Paul Burkholder; Yihong Li; Jon K. Reel; Charles Edward Ruegg; John M. Sullivan
Archive | 2005
Clive Gideon Diefenbacher; Thomas A. Engler; Hong-Yu Li; Sushant Malhotra; Jason Scott Sawyer; Yan Wang
Archive | 2003
Pamela Ann Albaugh; Jochen Ammenn; Timothy Paul Burkholder; Joshua Ryan Clayton; Scott Eugene Conner; Brian Eugene Cunningham; Thomas A. Engler; Kelly Wayne Furness; James Robert Henry; Yihong Li; Sushant Malhotra; Mark Joseph Tebbe; Guoxin Zhu
Archive | 2003
Douglas Wade Beight; Timothy Paul Burkholder; Todd Vincent Decollo; Alexander Glenn Godfrey; Charles Raymond Heap; Chi-Hsin Richard King; Hong-Yu Li; William Thomas Mcmillen; Jason Scott Sawyer; Yan Wang; Clive Gideon Diefenbacher; Thomas A. Engler; Sushant Malhotra; Sreenivasa Reedy Mundla
Archive | 2001
Thomas A. Engler; Kelly Wayne Furness; Sushant Malhotra; Stephen L. Briggs; Harold B. Brooks; David K. Clawson; Concepcion Sanchez-Martinez; Faming Zhang; Guoxin Zhu
Archive | 2003
Douglas Wade Beight; Timothy Paul Burkholder; Todd Vincent Decollo; Alexander Glenn Godfrey; Charles Raymond Heap; Chi-Hsin Richard King; Hong-Yu Li; William Thomas Mcmillen; Jason Scott Sawyer; Yan Wang; Clive Gideon Diefenbacher; Thomas A. Engler; Sushant Malhotra; Sreenivasa Reedy Mundla
