Susmit Kosta

Therapeutic plasma exchange: An effective treatment in ethylene dibromide poisoning cases

Ethylene dibromide (EDB) poisoning is very common in Central India and has fatal outcome. EDB is highly protein bound and, therefore, it is suggested that therapeutic plasma exchange (TPE) may be useful in removing drug from body shortly after ingestion before EDB metabolizes and causes severe end organ damage. The aim of our study is to find the effect of time of start of TPE on survival outcome of EDB poisoning cases.

Appraise the Health-Related Quality of Life among Trauma Patients

Background: Limb injures is revolve a life-changing event that can cause significant disruptions in many important areas of life. Objectives: The objective of our study was to appraise the Health Related Quality of Life (HRQOL) and psychosocial factors associated with pain and disability in patients following Upper limb (UL) and lower limb (LL) trauma patients Materials and methods: A sample of convenience 300 adult male and female patients who met the inclusion criteria was included. A short form (36) health status questionnaire was filled by a single author from each patient after one year of follow up. This part was utilized to assess the QOL among limbs traumas patients. Results: Intraclass correlation coefficients were greater than 0.7 in five of the eight domains of SF 36 except mental health, social function and general health. Chronbach’s α was higher than 0.8 all the domains except in social function domain. There was no difference in Health Related Quality of Life in patients with upper and lower limb trauma. However there was significant difference in 4 domains related to physical components of SF 36 survey form between male and females. Conclusion: Both upper and lower limb trauma similarly affects the Health Related Quality of Life in all age group of patients. Keywords: Sf-36, Trauma, HRQOL

Lipid profile in psoriasis: a case control study

Psoriasis is associated with an atherogenic lipid profile but longitudinal changes in lipids around disease onset are unknown. The purpose of our study is to examine the effect of psoriasis onset on serum lipid profiles. We compared changes in lipid profiles in a population based 94 patients with psoriasis vulgaris and 103 non-psoriasis subjects. The total cholesterol and low-density lipoprotein and high-density lipoprotein cholesterol levels were significantly higher in psoriatic patients (P < 0.05). Serum triglyceride levels were almost similar in both groups. This study, like other previous studies, shows that high serum lipid level is significantly more common in psoriasis. This fact may be responsible for higher prevalence of cardiovascular accident in psoriatic patients. It may be useful to do early screening and treatment of hyperlipidemia in psoriasis to prevent the atherosclerosis and its complications. These changes are unlikely to be caused by lipid profile treatment alone and require further exploration.