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Dive into the research topics where Suzana Arenhart Pessini is active.

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Featured researches published by Suzana Arenhart Pessini.


Menopause | 2009

Tamoxifen use and endometrial lesions : hysteroscopic, histological, and immunohistochemical findings in postmenopausal women with breast cancer

Raquel P. Dibi; Claudio G. Zettler; Suzana Arenhart Pessini; Alice Volpe Ayub; Suzane Beirão de Almeida; Gustavo Py Gomes da Silveira

Objective: To evaluate immunohistochemical, hysteroscopic, and histological findings in postmenopausal women taking tamoxifen for breast cancer. Methods: Forty postmenopausal women taking 20 mg/day tamoxifen for breast cancer underwent hysteroscopy and endometrial biopsy from January 2000 to December 2003. Medical records and paraffin blocks were analyzed retrospectively, and Ki-67, estrogen receptors (ERs), and progesterone receptors were measured using an immunohistochemical technique. Results: The mean ± SD age of the women was 59 ± 14 years at hysteroscopy (95% CI, 54.2-63.7) and 45.1 ± 7 years at menopause (95% CI, 42.6-47.6). Mean ± SD duration of tamoxifen therapy was 27.3 ± 16.5 months (95% CI, 22.0-32.5). Hysteroscopies were performed because of abnormal sonographic findings in 60% of the women and postmenopausal bleeding in 40%. The most common hysteroscopic and histological findings were endometrial polyps (32.5%) and atrophic endometria (22.5%). Immunohistochemistry showed that 85% of the women were progesterone receptor positive, 75% were ER positive, and 50% were Ki-67 positive. Endometrial polyps and polyps associated with atrophic endometrium were ER positive (P = 0.019). Results that were ER negative were more frequent in atrophic endometria (P = 0.01). The longer the time since menopause, the lower the Ki-67 expression in the endometrium was (P = 0.03). Ki-67 expression was greater in the endometrium of younger postmenopausal women (P = 0.01). Conclusions: The expression of steroid receptors in the endometrium was high in our series. All cases of endometrial polyps were ER positive. Estrogen receptors may play a major role in the development of endometrial polyps in postmenopausal women taking tamoxifen. Although most histological findings were benign, 22.5% were atrophic.


Gynecologic oncology reports | 2017

Paget's disease of the vulva: A review of 89 cases

Cherry O. Onaiwu; Mila Pontremoli Salcedo; Suzana Arenhart Pessini; Mark F. Munsell; Elizabeth E. Euscher; Kellie E. Reed; Kathleen M. Schmeler

The purpose of this study was to retrospectively review the clinical characteristics and outcomes of a series of women with Pagets disease of the vulva. A retrospective review was performed of 89 women with Pagets disease of the vulva evaluated at a single institution between 1966 and 2010. Medical records were reviewed for demographic information, clinical data, pathologic findings, treatment modalities and outcomes. We found that the primary treatment was surgery for 74 (83.1%) patients, with positive margins noted in 70.1% of cases. Five patients (5.6%) underwent topical treatment with imiquimod and/or 5-fluorouracil, one patient (1.1%) underwent laser ablation and treatment was unknown in 9 patients (10.1%). The majority of patients had multiple recurrences, with 18% having four or more recurrences. There were no significant differences in recurrence rates between patients who underwent surgery and those who did not. Furthermore, there was no association between positive margins following primary surgery and recurrence. Forty-one patients (46.1%) were diagnosed with 53 synchronous or metachronous cancers. Seven patients (7.9%) were found to have invasive vulvar cancer with 1 mm or more depth of invasion, but none of the patients died of Pagets disease or associated vulvar/vaginal cancer. Our findings suggest that the majority of patients with Pagets disease of the vulva develop multiple recurrences regardless of treatment modality or margin status. Alternatives to surgery are needed to better care for women with this disease.


Archive | 2018

Radical Vaginal Trachelectomy

Suzana Arenhart Pessini; Gustavo Py Gomes da Silveira; Denis Querleu

Cervical cancer is the fourth most common cancer in women, with estimated rates of incidence age standardized (ASRs) ranging from 5.5 per 100,000 in Australia/New Zealand to 42.7 in Eastern Africa. Around 84% of new cervical cancer and 87% of cervical cancer deaths occur in the less developed regions.


British Journal of Obstetrics and Gynaecology | 2018

Surgery in ovarian cancer – Brazilian Society of Surgical Oncology consensus

At Tsunoda; R Ribeiro; Rj Reis; Cem da Cunha Andrade; R Moretti Marques; G Baiocchi; F Fin; Ph Zanvettor; D Falcao; Tp Batista; Brb Azevedo; G Guitmann; Suzana Arenhart Pessini; Js Nunes; Lm Campbell; Jc Linhares; V Carneiro; Fjf Coimbra

Surgical management in epithelial ovarian cancer (EOC) has a significant impact in overall survival and progression‐free survival. The Brazilian Society of Surgical Oncology (BSSO) supported a taskforce of experts to reach a consensus: experienced and specialised trained surgeons, in cancer centres, provide the best EOC surgery. Laparoscopic and/or radiological staging prognosticates the possibility of complete cytoreduction (CC0) and helps to reduce unnecessary laparotomies. Surgical techniques were reviewed. Multidisciplinary input is essential for treatment planning. Quality assurance criteria are proposed and require national consensus. Genetic testing is mandatory. This consensus states the final recommendations from BSSO for management of EOC.


Journal of Minimally Invasive Gynecology | 2015

Laparoscopic Isthmocervical Cerclage with Mersilene Tape After Radical Vaginal Trachelectomy.

Gg Gomes-Da-Silveira; Suzana Arenhart Pessini; Gustavo Py Gomes da Silveira

performed via open, laparoscopic, and robotic approach. Uterine isthmovaginal anastomosis could be performed in vaginal or intra-corporeal approach and interrupted suture is used in most of the cases. A barbed suture is an attractive suture option that allows for easier and faster laparoscopic suturing by eliminating repeated knots and the need to maintain tension on the suture line. Here we present the case of successful uterine isthmo-vagina anastomosis with barbed suture in robotic radical trachelectomy. Uterine Isthmo-vaginal anastomosis is technically challenging when performed intra-corporeal approach and implementation of a barbed suture is able to decrease operative time without compromising surgical outcome.


Archives of Gynecology and Obstetrics | 2015

Prevalence of human papillomavirus infection in pregnant versus non-pregnant women in Brazil.

Mila Pontremoli Salcedo; Andrea Pires Souto Damin; Grasiela Agnes; Suzana Arenhart Pessini; Patrícia El Beitune; Cláudio Osmar Pereira Alexandre; Kathleen M. Schmeler; Gustavo Py Gomes da Silveira


Familial Cancer | 2010

Clinical and histomolecular endometrial tumor characterization of patients at-risk for Lynch syndrome in South of Brazil

Silvia Liliana Cossio; Patrícia Koehler-Santos; Suzana Arenhart Pessini; Heleuza Mónego; Maria Isabel Albano Edelweiss; Luíse Meurer; Abdellatif Errami; Jordy Coffa; Hugo Bock; Maria Luiza Saraiva-Pereira; Patricia Ashton-Prolla; João Carlos Prolla


Rev. méd. St. Casa | 2000

Cancer do endométrio

Suzana Arenhart Pessini; Áurea Terezinha Sandri; Sérgio Lago; Gustavo Py Gomes da Silveira; Sylvia Villar Mello Guimarães; Geraldo Gastal Gomes da Silveira


Femina | 2008

Chlamydia trachomatis e gestação

Mila Pontremoli Salcedo; Patrícia El Beitune; Antonio Celso Koehler Ayub; Carla Maria De Martini Vanin; Jacqueline Mori Lazzari; Suzana Arenhart Pessini; Suzane Beirão de Almeida; Raquel Papandreus Dibi; Cesar Pereira Lima


Journal of Minimally Invasive Gynecology | 2018

Castleman Disease in Young Woman

G. Gomes-da-Silveira; Suzana Arenhart Pessini; J. Amaral; R. Dibi; F. Escopelli

Collaboration


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Gustavo Py Gomes da Silveira

Universidade Federal de Ciências da Saúde de Porto Alegre

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Mila Pontremoli Salcedo

Universidade Federal de Ciências da Saúde de Porto Alegre

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Patrícia El Beitune

Universidade Federal do Rio Grande do Sul

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Antonio Celso Koehler Ayub

Universidade Federal de Ciências da Saúde de Porto Alegre

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Carla Maria De Martini Vanin

Universidade Federal de Ciências da Saúde de Porto Alegre

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João Carlos Prolla

Universidade Federal do Rio Grande do Sul

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Luíse Meurer

Universidade Federal do Rio Grande do Sul

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Silvia Liliana Cossio

Universidade Federal do Rio Grande do Sul

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Kathleen M. Schmeler

University of Texas MD Anderson Cancer Center

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At Tsunoda

Albert Einstein Hospital

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