T. A. Mastryukova

Synthesis and Comparative Analysis of the Steric and Supramolecular Structures of Diastereomers of 4,4-Bis(trifluoromethyl)-2-(fluoroalkoxy)-6,7-benzo-1,3,2λ5- dioxaphosphepin-5-one 2-Oxides

Reaction with hexafluoroacetone of 2-fluoroalkoxy-5,6-benzo-1,3,2-dioxophosphorinan-5-ones containing a chiral fluorinated exocyclic substituent on the phosphorus atom, with hexafluoroacetone leads to formation of 4,4-bis(trifluoromethyl)-6,7-benzo-1,4,2-dioxaphosphepines with a high regio- and stereoselectivity. The configuration of all isolated individual diastereomers was established by X-ray diffraction. The molecular and supramolecular structure of the compounds were examined in terms of the proposed model that takes account of the revealed effect of separation of hydrophilic and lipophilic regions in the crystal.

Pishchimuka's Intramolecular Rearrangement. The General Method for the Synthesis of 2-Oxo-1,2λ5-thiaphoapholanes and Thiaphosphorinanes

A new method is developed for the synthesis of 2-substituted 2-oxo-1,2λ5-thiaphospholanes and thiaphosphorinanes (thiolphostones) on the basis of intramolecular Pishchimuka rearrangement of thiophosphonic and thiophosphinic esters with ω-chloroalkyl substituents at the phosphorus atom. Intermediate compound in the Pishchimuka rearrangement, 2-ethyl-2-ethoxy-1,2λ4-thiaphospholanium perchlorate, was isolated.

SYNTHESIS OF N-PHOSPHORYLATED AMINOACIDS

Abstract N-Phosphorylated α-aminoacids have been synthesized by the reaction of organophosphoryl chlorides with O,N-bis(trimethylsilylated) derivatives of the corresponding aminoacids.

Alkylation of Hydrothiophosphoryl Compounds by Digalogenoalkanes Under Phase Transfer Caralysis Conditions

Abstract The course of reactions of hydrothiophosphotyl compounds with dihalogenoalkanee under PTC conditions depends both on the nature of halogen atom and the length of the alkylene chain.I reacts with CH2Br2 to yield Ph2P(S)CH3; with ICH2Cl Ph2P(S)CH2Cl is formed.

NEW COMPLEXES OF PALLADIUM(II) CHLORIDE WITH CHELATING PHOSPHORUS, SULFUR CONTAINING LIGANDS

Abstract New palladium(II) coordination compounds PdLCl2 and PdL2Cl2 with chelating ligands containing thiophosphoryl groups along with carbamoyl or thiocarbamoyl groups were synthesized. The structures of the complexes in solutions and in solid were studied by electronic and IR spectroscopy, conductometry, and FD mass spectrometry. Transformations of the complex PdL3 2Cl2 under a strong electric field were investigated.

Synthesis of thiophosphoryl-substituted derivatives of cycloalkanecarboxylic acids

The 1-thiophosphorylated esters and nitriles of cycloalkanecarboxylic acids were obtained both by the direct reaction of derivatives of thiophosphorylacetic acids with α,ω-dihalogenoalkanes in the K2CO3/DMSO heterophasic system, and as a result of the reaction of the corresponding oxygen compounds with the Louson reagent.

Some properties of 1-phosphorus(IV)-substituted cycloalkanecarboxylic acids and their derivatives

An x-ray structural study of single crystals of 1-diphenylphosphinyl-cyclo-propane- and 1-diphenylphosphinylcyclobutanecarboxylic acids was conducted. 1-Phosphorylated cycloalkanecarboxylic acid amides were obtained from the corresponding acids by the reaction with thionyl chloride with subsequent treatment with primary and secondary amines. It was shown that the reaction of 1-phosphorylated 1-functional substituted cycloalkanes with trimethylbromosilane takes place with preservation of the cyclic structure and yields phosphoric acid silyl esters, and the corresponding cycloalkylphosphonic and cycloalkylphosphinic acids were synthesized by their hydrolysis in soft conditions.

Prototropic Tautomerism in Phosphoryl-Hydroxyylide and Thiophosphoryl-Mercaptoylide Systems

Abstract Two new types of tautomerism are discussed: phosphoryl-hydroxyylide and thiophosphoryl-mercaptoylide tautomerism.

Nitration of alkenylphosphonates with nitrogen tetraoxide

A new method was developed for the synthesis of organophosphorus nitro compounds, which consists in the direct nitration of alkenylphosphonates with N2O4.

Hydrogen bonding and association of certain phosphadepsipeptides

1. n nIR spectroscopy has been used to study intermolecular and intramolecular hydrogen bonding in certain phosphadepsipeptides. n n n n n2. n nIn the condensed phase, these compounds associate through the formation of intermolecular hydrogen bonds in a process involving participation of the COOH and NH groups. n n n n n3. n nIn solution, it is only those compounds which contain open COOH groups which undergo appreciable association; the remaining compounds form intramolecular hydrogen bonds in dilute solution, the bonding process involving NH group participation.