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Dive into the research topics where T.J. Merimee is active.

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Featured researches published by T.J. Merimee.


Metabolism-clinical and Experimental | 1969

Effect of arginine on insulin release in vitro

Paul J. Edgar; D. Rabinowitz; T.J. Merimee; E. Almogela

Abstract The effect of arginine on insulin release was studied by observing the effect of glucose and arginine, both singly and together, on the release of immuno insulin from pieces of rabbit pancreas incubated in bicarbonate buffer. Arginine alone (1.0–3.0 mg./ml.) failed to stimulate insulin release above control levels, whereas the same pancreas when subsequently exposed to a glucose concentration of 3.0 or 3.5 mg./ml. showed a convincing response. When ariginine was tested in buffer fortified with 1.5 mg./ml. glucose, it significantly enhanced insulin release. These data suggest that arginine influences insulin release by enhancing the stimulatory effect of the glucose metabolite(s) which triggers insulin release in the B-cell.


The Lancet | 1966

PATTERNS OF HORMONAL RELEASE AFTER GLUCOSE, PROTEIN, AND GLUCOSE PLUS PROTEIN

D. Rabinowitz; T.J. Merimee; R. Maffezzoli; John A. Burgess


The Lancet | 1965

EFFECT OF ARGININE ON SERUM-LEVELS OF HUMAN GROWTH-HORMONE

T.J. Merimee; DavidA. Lillicrap; D. Rabinowitz


The Journal of Clinical Endocrinology and Metabolism | 1966

Sex-Determined Variation in Serum Insulin and Growth Hormone Response to Amino Acid Stimulation

T.J. Merimee; John A. Burgess; D. Rabinowitz


The Journal of Clinical Endocrinology and Metabolism | 1966

Growth Hormone and Insulin Release After Arginine: Indifference to Hyperglycemia and Epinephrine

D. Rabinowitz; T.J. Merimee; John A. Burgess; L. Riggs


The Lancet | 1966

ARGININE INFUSION IN MATURITY-ONSET DIABETES MELLITUS: Defective Output of Insulin and of Growth Hormone

T.J. Merimee; John A. Burgess; D. Rabinowitz


The Lancet | 1968

An unusual variety of endocrine dwarfism: subresponsiveness to growth hormone in a sexually mature dwarf.

T.J. Merimee; J. G. Hall; D. Rabinowitz; V.A. Mckusick; D.L. Rimoin


Endocrinology | 1969

Effects of Amino Acids on Insulin Release from Excised Rabbit Pancreas1

Paul J. Edgar; D. Rabinowitz; T.J. Merimee


The Lancet | 1968

Metabolic effects of human growth hormone in the African pygmy.

T.J. Merimee; DavidL. Rimoin; L.C Cavalli-Sforza; D. Rabinowitz; VictorA. Mckusick


The Journal of Clinical Endocrinology and Metabolism | 1970

Isolated Growth Hormone Deficiency: Studies in Pregnancy1

John E. Tyson; Allan C. Barnes; T.J. Merimee; Victor A. McKusick

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D. Rabinowitz

Johns Hopkins University School of Medicine

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John A. Burgess

Johns Hopkins University School of Medicine

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Paul J. Edgar

Johns Hopkins University School of Medicine

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Allan C. Barnes

Johns Hopkins University School of Medicine

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D.L. Rimoin

Washington University in St. Louis

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DavidA. Lillicrap

Johns Hopkins University School of Medicine

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DavidL. Rimoin

Johns Hopkins University School of Medicine

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E. Almogela

Johns Hopkins University School of Medicine

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John E. Tyson

Johns Hopkins University School of Medicine

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L. Riggs

Johns Hopkins University School of Medicine

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