Tae K. Song | Researchain

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Featured researches published by Tae K. Song.

Bioorganic & Medicinal Chemistry Letters | 1995

Synthesis and pharmacological activity of conformationally restricted, acetylenic retinoid analogs

Roshantha A. S. Chandraratna; Samuel J. Gillett; Tae K. Song; John Attard; Sagar Vuligonda; Michael E. Garst; Taghreed Arefieg; Daniel W. Gil; Larry A. Wheeler

Abstract The biological activity of retinoids are determined by their ability to activate one or more of six nuclear retinoid receptors (RARs and RXRs). We describe rigid, acetylenic retinoids that selectively transactivate through the RARs and RAR/Gg subtypes and demonstrate their potent anti-proliferative activity in the skin.

Archive | 1997

Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity

Tae K. Song; Min Teng; Roshantha A. Chandraratna

Journal of Medicinal Chemistry | 1995

Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors

Alan T. Johnson; Elliott S. Klein; Samuel J. Gillett; Liming Wang; Tae K. Song; Mary E. Pino; Roshantha A. S. Chandraratna

Archive | 1994

Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl of heteroaryl group having retinoid-like biological activity

Vidyasagar Vuligonda; Richard L. Beard; Alan T. Johnson; Min Teng; Tae K. Song; Roshantha A. Chandraratna

Journal of Medicinal Chemistry | 1996

Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid.

Richard L. Beard; Diana F. Colon; Tae K. Song; Peter J. A. Davies; Devendra M. Kochhar; Roshantha A. S. Chandraratna

Journal of Medicinal Chemistry | 1995

Synthesis and Structure-Activity Relationships of Stilbene Retinoid Analogs Substituted with Heteroaromatic Carboxylic Acids

Richard L. Beard; Roshantha A. S. Chandraratna; Diana F. Colon; Samuel J. Gillett; Henry E; Marler Dk; Tae K. Song; Denys L; Michael E. Garst; Arefieg T

Archive | 1994

Acetylenes disubstituted with hydroxyaryl and aryl or heteroaryl groups having retinoid-like biological activity

Tae K. Song; Roshantha A. Chandraratna

Archive | 1996

Acetylenes disubstituted with 2-tetrahydropyranoxyaryl and aryl or heteroaryl groups having retinoid-like biological activity

Tae K. Song; Roshantha A. Chandraratna

Archive | 1998

Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity

Tae K. Song; Min Teng; Roshantha A. Chandraratna

Archive | 1997

Substituted tetrahydronaphthalene and dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity

Vidyasagar Vuligonda; Min Teng; Richard L. Beard; Alan T. Johnson; Yuan Lin; Roshantha A. Chandraratna; Tae K. Song; Harold N. Wong; Tien T. Duong; Samuel J. Gillett

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